China journal of Chinese materia medica 

About: China journal of Chinese materia medica is an academic journal. The journal publishes majorly in the area(s): Column chromatography & Traditional Chinese medicine. It has an ISSN identifier of 1001-5302. Over the lifetime, 8736 publications have been published receiving 30934 citations.

Review of pharmacological effects of Glycyrrhiza Radix and its bioactive compounds

Abstract: Glycyrrhiza Radix is a commonly used Chinese herbal medicine, derived from the dried roots and rhizomes of Glycyrrhiza uralensis, G. glabra and G. inflata. The main bioactive constituents of licorice are triterpene saponins and flavonoids. There are various types of pharmacological properties of licorice are proved, including antiulcer, antiinflammation, spasmolysis, antioxidative, contravariance, antiviral, anticancer activities, hepatoprotective, eliminating phlegm and reinforcing remembrance effects. Triterpene saponins are the main components of Glycyrrhiza Radix and its pharmacological activities are comparatively thorough and clear. In recent years, licorice flavonoids, proved to have a variety of pharmacological activities, become one of the hot of pharmacological studies. In this review, we summarized the latest five-year progress in pharmacological activities of licorice extract, its triterpenoid saponins and flavonoids, and experimental researches indicated that licorice had both accommodation and protection activity on the digestive system, respiratory system, nervous system, and endocrine system, etc.

Antiviral activity of tannin from the pericarp of Punica granatum L. against genital herpes virus in vitro

Abstract: Based on cell culture techniques this study has demonstrated that tannin from the pericarp of Punica granatum is an effective component against genital herpes virus (HSV-2). The tannin not only inhibits HSV-2 replication, but also shows stronger effects of killing virus and blocking its absorption to cells.

[Studies of commonly used traditional medicine-ginger].

Abstract: To review the chemical, pharmacological, studies on ginger (Zingiber officinale) in the last ten years, and also its processing history and clinical uses. Gingerols and related compounds in ginger have many pharmacological activities. Chemical studies should be given sufficiently emphasis, and advances of the chemical study will promote the other related researches to develop in depth.

[Network target: a starting point for traditional Chinese medicine network pharmacology].

Abstract: Understanding the interactions between numerous chemical compounds of herbs or herbal formulae and complex biological systems related with diseases or traditional Chinese medicine (TCM) syndromes is one of great dilemmas in current studies on TCM. To address such a difficult issue, we propose a novel concept and methodology of "Network Target" based on our previous works and from the perspective of network pharmacology as well as systems biology. The network target treats a disease-specific biomolecular network as a target to help design and predict the best possible treatments. Focused on mapping disease phenotypes and herbal compounds into biomolecular networks and then calculating, analyzing and predicting the mechanism of their mutual interactions, the network target approaches will facilitate discovery of effective compounds and their combinations, elucidation of mechanistic relationships between herbal formulae and diseases or TCM syndromes, and development of rational drug designs for TCM. In this paper, our recent progresses on the methodology of Network Target and its applications in herbal medicine are reviewed to provide reference for the coming TCM network pharmacology.

Studies on chemical constituents in fruits of Tibetan medicine Phyllanthus emblica

Abstract: [] Objective: To investigate the chemical constituents of Tibetan medicine Phyllanthus emblica. Method: Various chromatographic techniques were employed for isolation and purification of the constituents, and the structures were elucidated by chemical and spectral analyses. Result: 11 compounds were isolated and identified as gallic acid( I ), ellagic acid( II ), 1-O-galloyl-β D-glucose( III ), 3, 6-di-O-galloyl-D-glucose ( IV ), chebulinic acid ( V ), quercetin ( VI ), chebulagic acid ( VII ), corilagin ( VIII ), 3-ethylgollic acid (3-ethoxy-4, 5-dihydroxy-benzoic acid, IX ), isostrictiniin ( X ), 1, 6-di-O-galloyl-β-D-glucose ( XI ). Conclusion: 3-ethylgallic acid(3-ethoxy-4,5-dihydroxy-benzoic acid) is a novel compound, and isostrictiniin was found from P. emblica for the first time.