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Showing papers in "Chinese Journal of Behavioral Medicine and Brain Science in 2006"


Journal ArticleDOI
TL;DR: Wang et al. as discussed by the authors proposed a method to solve the problem of "不协调理论构想得到了数据
Abstract: 目的 针对自杀压力不协调理论中的价值观冲突带来的压力进行了初步的检验.方法运用自编问卷,测量了487名被试由于价值观冲突而产生的不协调压力.结果自杀的压力不协调理论构想得到了数据结果的支持.压力1与压力2相关显著(r=0.266,P<0.001).压力量表能够测量出由儒家性别偏好和性别平等观念冲突带来的不协调压力.Alpha系数介于0.688~0.882之间.结论为测量中国农村妇女的价值观冲突带来的不协调压力而设计的测量工具有较好的信度和效度.尽管如此,还需在将来的研究中扩大样本、精细工具从而对本理论做更深入的验证。

19 citations


Journal Article
TL;DR: Instruments for measuring rural women’s value conflicts in China have acceptable reliability and validity scores, however, more rigorous studies with larger samples are needed to further examine the strain theory of suicide.
Abstract: ObjectiveIn this current study, the strain out of differential values, which is the most complex one among the four types of strain, was examined. Methods487 college students and rural high school students were assessed by questionnaires. ResultsThe theoretical frame was basically supported by the data collected in rural China.Strain 1 correlated with strain 2 significantly(r=0.266,P0.001).Alpha coefficients range between 0.688 and 0.882.ConclusionInstruments for measuring rural women’s value conflicts in China have acceptable reliability and validity scores.However, more rigorous studies with larger samples are needed to further examine the strain theory of suicide.

16 citations


Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and awareness of benefits and risks are all important.
Abstract: 目的 完成清晨型与夜晚型评定量表(MEQ)中文版的引进工作.方法 首先进行MEQ量表项目的 翻译定稿,然后应用中文版评定163名健康受试者的日周期倾向,并通过两周睡眠记录表记录他们的睡眠习惯.根据测量的结果,进行量表信度与效度检验,并试图寻找其划界点.结果 MEQ量表中文版的19个条目被确定为两个因子:睡眠时相因子和最佳表现时间因子.中文版的划界点:绝对清晨型:70~86、中度清晨型:63~69、中间型:50~62、中度夜晚型:43~49、绝对夜晚型:16~42.中文版的Chronbach α系数为0.701~0.738、Spearman-Brown分半信度为0.584~0.697、重测信度为0.638~0.831,均达到了心理测量学可接受的水平.结论 MEQ量表中文版有良好的心理测量学特征,新划界点可以有效地区分清晨型和夜晚型。

13 citations


Journal ArticleDOI
TL;DR: 方法整群抽取安徽省无为县某地区两所农村小学,
Abstract: 目的 了解安徽省农村地区留守儿童孤独感现况及其影响因素.方法整群抽取安徽省无为县某地区两所农村小学,共882名3~6年级小学生(男472名,女410名),其中留守儿童489人.采用儿童孤独量表和自编调查表进行问卷调查.结果在被调查3~6年级小学留守儿童中存在孤独感有86人,占17.6%,孤独感发生率男、女相同都是17.6%.不同年级、年龄间的孤独感发生率的差异有显著性(P<0.05),且随年级增加,孤独感发生率呈下降趋势(χ2趋势=5.970,P=0.015).留守儿童孤独感可能与成绩、学习困难程度、健康状况、父母亲教育方式、父母间关系和老师教育方式等因素有一定的关系.结论农村地区留守儿童中存在一定程度的孤独感问题,老师和家长应以正确的态度和方法对待留守儿童,以减少留守儿童的孤独感。

12 citations


Journal Article
TL;DR: Overall, most diabetics reported a moderate to low level of self-management and quality of life, and there was a moderate and positive correlation between self- management andquality of life.
Abstract: ObjectiveTo examine the relationship between self-management and quality of life in diabetics. MethodsA descriptive and correlation design was used in this study. 214 subjects completed the University of Michigan Diabetes Research and Training Center Diabetes Care Profile (DCP), the Diabetes Knowledge Test (DKT), and the Diabetes Patients’ Quality of Life in China (DSQL).Results(1) The diabetics reported higher levels of self-management for 6 of 11 domains. They were self-management ability, medical barriers, exercise barriers, attitude towards diabetes, self-management adherence, and importance of self-management. However, they reported lower levels of self-management for other 5 domains. They were diet adherence, monitoring barriers, control problems, understanding diabetes knowledge, and DKT scores. (2) The mean score of quality of life by DSQL was 54.75±13.05. (3) The absolute value of correlation coefficients between 10 domains’ mean scores of self-management (except of monitoring barriers) and DSQL total score ranged from 0.174 to 0.641. There was a positive correlation between self-management and quality of life in patients with diabetes. ConclusionOverall, most diabetics reported a moderate to low level of self-management and quality of life. There was a moderate and positive correlation between self-management and quality of life.

10 citations


Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and awareness of benefits, will all be important.
Abstract: 目的 探讨糖尿病患者自我管理水平和生存质量的相关性.方法采用描述性相关性研究,用密西根糖尿病管理评定量表(DCP)、密西根糖尿病知识测试问卷(DKT)和中国糖尿病患者生存质量特异性量表(DSQL)对214例1型和2型糖尿病患者进行问卷调查.结果(1)糖尿病患者的自我管理处于较高水平的因子有:自我管理能力、药物治疗问题、运动锻炼问题、对疾病的态度、自我管理坚持性及自我管理重要性认识;而较低水平的因子有:饮食依从性、血糖或尿糖检测问题、病情控制问题、糖尿病知识的理解自评及得分.(2)糖尿病患者生存质量的DSQL均值为(54.75±13.05)分,处于中等水平.(3)除血糖或尿糖检测问题因子外,自我管理水平的各个因子与生存质量的DSQL评分存在相关性(r=0.174~0.641,P<0.05),表现为患者在上述因子的自我管理水平越高,其生存质量水平越高.结论糖尿病患者自我管理水平普遍与生存质量存在中等程度的正相关。

9 citations


Journal Article
TL;DR: The degrees and frequencies of loneliness among left-behind children in the rural area were high and school and parents should provide correct educational methods to help children keeping mental health.
Abstract: Objective To realize the current situation and risk factors on the loneliness for left-behind children in rural area of Anhui.MethodsA questionnaire was conducted among two rural primary schools' 882 grade3 to 6 students(male:472,female:410) by the cluster sampling methods based on the Children's Loneliness Scale(CLS).489 of them was left-behind children.ResultsTotal rate of loneliness for left-behind children was 17.6%.Different sex had no difference on the loneliness(17.6%).There were significant differences among grades and ages(P0.05).Loneliness status had a downtrend with grades(P=0.015).Loneliness among left-behind children related to the difficult level of learning,health status,parents' educational methods and relationship between parents,etc.ConclusionThe degrees and frequencies of loneliness among left-behind children in the rural area were high.School and parents should provide correct educational methods to help children keeping mental health.

9 citations


Journal ArticleDOI
TL;DR: The investigation of the occurrence and influential factors of post-traumatic stress disorder in SARS patients, hospital staffs and the public expo sed to SARS concludes that all three groups of people exposed o SARS exhibit PTSD symptom.
Abstract: Objective This paper focuses on the investigation of the occurrence and influential factors of post-traumatic stress disorder (PTSD)in SARS patients, hospital staffs and the public expo sed to SARS. Methodes Three groups were assessed by scale of self-compiled stressor Questionnaire, impact of event scale-revised (IES-R) , PSSS, SCSQ, SES and EPQ. Results 1. The incidence of PTSD symptoms in the three groups were 55.1% ,25.8 % and 31.18 %. 2. The main cause of the different incidence was the difference of the stressor intensity and characters. Negative coping was the risk factor of SARS patients and the public; Self-esteem was the protected factor of SARS patients and the hospital staffs; Social support was a protected factor on the hospital staffs. 3. Comparing to the first investigate in September,2003 ,the data of follow-up study in September,2004 showed that the prevalence items significant decreased. Conclusions 1. The investigation concludes that all three groups of people exposed o SARS exhibit PTSD symptom. SARS patients have the highest occurrence ( P < 0.01 ). 2. The main influencing factors of different incidence of PTSD in different groups are intensities and characteristics of stressors. Different people who had PTSD symptoms have different influencing factors. 3. With the change of time , the PTSD symptoms significant relieve with the attenuation gradually of exposure degree of stressor. Key words: Severe acute respiratory syndrome; Stress disorder; Post-traumatic

6 citations


Journal Article
TL;DR: This article developed a cross-culture revision of attributional style questionnaire (ASQ) and measured467 undergraduates were measured with Beck Depression Inventory (BDI) and ASQ, and reliability analysis confirms that alpha coefficients ranged from 0.4~0.9 with the total coefficient got at 0.8429.
Abstract: ObjectiveTo develop a cross-culture revision of attributional style questionnaire (ASQ). Methods467 undergraduates were measured with Beck Depression Inventory(BDI)and ASQ.Results①Reliability analysis confirms that alpha coefficients ranged from 0.4~0.9 with the total coefficient got at 0.8429.②Graduates on different depressed level have distinctly different attributional style. But unstable relationships exist on aspects of good events and internal-external dimension. ConclusionThe psychometric properties of the questionnaire developed in the current study are acceptable.

6 citations


Journal Article
TL;DR: Health Qigong-Yi Jin Jing can slow down intelligence decline of the aged through improving quickness of thought and action, short-term memory and attention quality.
Abstract: ObjectiveTo analyze the effect of the Health Qigong-Yi Jin Jing on the intelligence decline of the aged. MethodsA comparison analyze was made between the practice team and the contrast one before and after 6-months practice through a computer-assisted test of intelligence level to physiological age. ResultThere was no significant difference between two teams. the test result of the team before and after-6-months practice respectively is displayed as follows,the speed at mental arithmetic (second) 5.13±2.17 and 4.21±1.55,the symbol-figure(second) 23.29±6.08 and 19.88±4.73,the act reaction (second) 1.58±0.30 and 4±0.23,the two-digit remaining span (digit) 2.73±0.94 and 3.21±0.86,the intelligent physiological age(year) 61.53±6.29 and 59.22±6.00,and the aging degree (index)-0.15±0.83 and-0.69±0.76.and there were significant differences between all this counterparts. There were no observable change in the contrast. ConclusionHealth Qigong-Yi Jin Jing can slow down intelligence decline of the aged through improving quickness of thought and action,short-term memory and attention quality.

6 citations


Journal Article
TL;DR: The Chinese Adolescents Alcohol Expectancy Questionnaire was developed according to the purpose and met the need of measure alcohol expectancy and showed different drinkers had significant different alcohol expectancy.
Abstract: ObjectiveTo develop Alcohol Expectancy Questionnaire for Chinese Adolescents.MethodsThe theory and methodology in developing rating scale was used to establish the instrument.The alcohol expectancy data from 919 high school students were measured to evaluate the scale. ResultsThe 97-item Alcohol Expectancy Questionnaire was formed including eight domains: global negative (35 items), positive social perception(14 items), tension reduction and pleasure(11 items),social courtesy(10 items), negative personal effects(7 items),negative perception(7 items), social facilitation(5 items) and beneficial drinking(8 items). The Cronbach's (values were between 0.67 and 0.94, and the minimum correlation coefficients between each item and the score of its domain was 0.59, while the maximum was 0.52 with other domains. Exploratory principal component analysis identified seventeen factors that made up the scale's eight domains, explaining 75.9% of total variance. Validity test showed different drinkers had significant different alcohol expectancy.ConclusionThe Chinese Adolescents Alcohol Expectancy Questionnaire was developed according to our purpose and met the need of measure alcohol expectancy.

Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and awareness of risks, will all be important.
Abstract: 目的 探讨阿立哌唑治疗抗精神病药物(APS)所致高催乳素血症的疗效及安全性.方法 60例APS所致高催乳素血症患者,维持原APS治疗方案.随机分组后,分别加用阿立哌唑5mg(30例)及安慰剂(30例)进行对照治疗,疗程6周.于治疗前、治疗后6周检测催乳素(PRL);观察高催乳素血症临床症状变化情况;以简明精神病量表(BPRS)及副反应量表(TESS)评定对原APS治疗疗效的影响及其他不良反应.结果 阿立哌唑组研究结束时PRL[(27.5±8.2)μg·L-1]较基线[(148.7±45.5)μg·L-1]下降,差异具有显著性(P<0.001);安慰剂组研究结束时PRL[(122.4±72.2)μg·L-1]与基线[(134.4±58.8)μg·L-1]比较,差异无显著性(P>0.05);阿立哌唑组月经恢复(27/28)、自发泌乳消失(16/16),安慰剂组则均无改善.2组不良反应均轻,总体发生率相当,对原APS治疗的疗效均无不良影响.结论 阿立哌唑治疗抗精神药物所致高泌乳血症有效、安全。

Journal Article
TL;DR: The insomnia patients not only have lower sleep quality, but also have more mental health situations and there are varying features of PSG parameters with patients insomnia.
Abstract: ObjectiveTo explore the relationship between the sleep quality and mental health status in patients with insomnia,and to explore the significance of the quantitative analysis of polysomnograms in evaluating the objective and subjective situation of sleep in insomniacs. Methods98 patients of insomnia and 98 normal controls were measured with Pittsburgh Sleep Quality Index(PSQI),SCL-90 and the all-night polysomnography(PSG) recordings were conducted . The sleep latency , total sleep time and sleep efficiency were rated after getting up the next morning. ResultsThere were significant differences in sleep quality and in total score of SCL-90,factor-score of somatization,depression,anxiety and dyssomnia between the patients with insomnia and the normal controls. A prolonged sleep latency, decreased total sleep duration, increased awake frequency, low sleep efficiency, abnormal sleep architecture such as decreased REM sleep was found in patients with insomnia. The difference between subjective sleep and objective estimates of sleep was significant. ConclusionThe insomnia patients not only have lower sleep quality , but also have more mental health situations. There are varying features of PSG parameters with patients insomnia. Observation and quantitative analysis of polysomnograms might distinguish subjective insomnia from objective insomnia. There are have differences between subjective and objective estimates of sleep in the insomniacs .The insomniacs presents a tendency to overestimate the sleep latency and underestimate the sleep time.

Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and awareness of benefits and risks are all important.
Abstract: 目的 探讨"健身气功·易筋经"对老年智能老化程度的影响.方法 采用智能生理年龄测试软件,通过微机人机对话方式分别于练功6个月前、后对练功组和对照组测试.结果 练功前智能生理年龄测试的7个单项以及智能生理年龄和老化度2组间差异无显著性.练功组于练功6个月前、后各项测试结果分别为:心算速度(5.13±2.17)s和(4.21±1.55)s、数字符号(23.29±6.08)s和(19.88±4.73)s、动作反应(1.58±0.30)s和(1.44±0.23)s、两位数字记忆广度(2.73±0.94)位和(3.21±0.86)位、智能生理年龄(61.53±6.29)岁和(59.22±6.00)岁、老化度(-0.15±0.83)和(-0.69±0.76),差异有显著性;而对照组6个月前、后相比差异无显著性.结论 通过"健身气功·易筋经"的锻炼能够明显提高老人的思维敏捷性、动作灵活性、短时记忆力和注意品质,确实能够起到延缓中老年人智能衰退的作用。

Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and awareness of benefits and risks are all important.
Abstract: 目的 调查医护人员慢性疲劳综合征(CFS)情况,分析其与生活事件、个性和应付方式等心理社会因素关系.方法对615名医护人员进行CFS和心理社会因素调查,将符合诊断标准的117人作为病例组,其他498人作为对照组,进行非条件Logistic回归病例对照研究.对39个变量进行单因素,对有显著性关联的14个因素进行变量调整,将有显著意义的10个变量拟合主效应模型.结果经常感到疲劳的医护人员232人,伴头痛219人、肌肉酸痛207人和睡眠障碍180人.危险因素包括急诊重症科(or=4.50)、内科(or=2.44)、护士(or=1.86)和年龄(or=1.40);聪慧(or=4.61)、怀疑(or=3.44)和有恒(or=1.75);正性社交其他类生活事件(or=1.58)和正性工作类学习生活事件(or=1.30);退避(or=1.52)和自责(or=1.43).结论医护人员是CFS的高危人群;心理社会因素是CFS的危险因素。

Journal ArticleDOI
TL;DR: The future of DV is in your hands, not the company you work for.
Abstract: 目的 探讨家庭暴力(DV)的社会人口学特征.方法采取多级分层随机抽样方法,用自编DV综合问卷,对300户有暴力家庭,以及按照家庭结构配对选取的300户无暴力家庭有关成员作调查访谈.结果施暴者与受虐者年龄组构成比均以30~39岁最高(分别为40.3%和27.1%),文化程度构成比均以小学以下为最高(分别为32.2%和43.1%).施暴者男性多于女性(70.1% vs 29.9%),受虐者女性多于男性(67.0% vs. 33.0%),两组性别差异有显著性(P <0.001),成年男性施暴的危险度是女性的5.0倍.成年施暴者受教育年限[(8.9±4.7)年]高于受虐者[(7.5±5.2)年](P <0.01),但低于对照组(P <0.05).成年施暴者月经济收入[(709.7±796.4)元]及其占家庭总收入比例[(24.1±32.2)%]均显著高于受虐组[(477.5±489.1)元和(17.3±26.0)%](P <0.05或P <0.01),但低于施暴对照组(P <0.05或P <0.01).男性自评经济状况差、占家庭经济收入比例低是DV的危险因子.结论家庭暴力高发年龄为以30~39岁,施暴者为男性居多,受虐者大多为女性,施暴者与受虐者的文化程度与经济收入均较低,特别是经济收入占家庭总收入比例低者容易受虐。

Journal ArticleDOI
TL;DR: In this article, the authors propose a framework to improve the quality of the training environment of a teacher's training program by using the knowledge from the teacher's own experience.http://www.saliency.org.
Abstract: 目的 编制大学生心理症状量表,为教育、临床和社会评估提供测评工具.方法 通过文献资料法归纳大学生的常见心理症状,从症状自评量表(SCL-90)等常用量表中提取项目建立项目库,以此为基础编制大学生常见心理症状量表.结果 全量表由自卑、人际过敏、网络成瘾、抑郁和敌对5个维度组成,α系数为0.93,分半信度系数为0.91,重测信度为0.68;与自尊、生活满意度和大学生心理健康量表的积极维度的相关为-0.455、-0.399和-0.409,与大学生心理健康量表的消极维度相关为0.571.大学生最突出的症状是抑郁和自卑,网络成瘾存在性别和年级差异.结论 大学生心理症状量表基本符合心理测量学的标准并具有良好的信度和效度。

Journal Article
TL;DR: Under DOTS tactics, the supervisor should pay close attention to tuberculosis patient's mental hygiene in floating population, especially to unmarried workers in Shenzhen for the first time.
Abstract: ObjectiveTo explore the state of social support and it's relevant influence factor of the tuberculosis patient in floating population.MethodsThe SSRS was applied to the pulmonary tuberculosis patient in floating population using face to face interview in Shenzhen 6 districts,and analyse the effect of the sex , marital status, inhabit time , working mobility ,etc.to the social support in tuberculosis patient. ResultsThe every factor score hadn't significance difference in floating population tuberculosis patient in sex, inhabit time (P0.05).There were significance difference in the score in total(unmarried 34.169±5.923,married 36.966±7.385), subjective support(unmarried 6.542±2.056,married 7.522±2.595) and objective support(unmarried 20.724±3.924,married 22.810±5.390) between the different marital status(P0.05). There were significance difference in the score in total(floating 34.994±6.166)), subjective support(floating 6.641±2.283)) and objective support(floating 21.813±4.107)in the different work mobility (P0.05).There are not significance difference in the degree of support utilizing (P0.05 ).ConclusionUnder DOTS tactics, the supervisor should pay close attention to tuberculosis patient's mental hygiene in floating population, especially to unmarried workers in Shenzhen for the first time.

Journal Article
TL;DR: In this paper, the effect of early systemic intervention on psychosocial development in non-sibling children was explored and the results showed that the earlier they were intervened by research program the better were the tendency of psycho-social development and behavior.
Abstract: Objective To explore the effect of early systemic intervention on psychosocial development in non-sibling children.Methods 315 non-sibling children were chosen at random from 9 cities in China and received intervention under the Guide of Different Stages from 0 to 6 years old.Other 300 children were collected as control matched by age,sex and family background.The standard instruments used to assess the effect of intervention were Personality Tendency Scale for Children,Achenbach Children Behavior Checklist,Chinese Binet Intelligent Test,Adaptive Behavior Scales and Temperament Questionnaire.Results The behavior problems according to CBCL in the intervention group were significantly lower than that of control group(21.95±16.08,26.17± 18.88;P0.01).The tendency of psychosocial development,the average IQ,the temperament and the adaptability of intervention group were significantly better than that of control group(P0.05 or 0.01).The earlier they were intervened by research program the better were the tendency of psychosocial development and behavior.Conclusion Early systemic intervention is benefit to the psychosocial development of non-sibling children.The duration between 0 and 6 years old is the golden period in developing healthy personality.

Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and awareness of risks and benefits are important.
Abstract: 目的 探讨儿童期虐待对中专学生心理健康和社交功能的影响,并对影响社交功能的有关因素进行分析.方法对符合入组标准的受虐待组和对照组学生各90名,采用症状自评量表(SCL-90)、德克萨斯社交行为问卷(TSBI)、人际信任量表(ITS)、社交回避及苦恼量表(SAD)和自尊量表(SES)进行测评,比较两组之间各量表分的差异,并进行社交行为影响因素的相关分析.结果受虐待组学生SAD总分、SCL-90总均分及各因子分均明显高于对照组:SAD总分[(15.13±4.82)分vs(9.12±5.18)分,P<0.01];SCL-90总均分[(1.59±0.57)分vs(1.84±0.61)分,P<0.01].其SES分[(25.15±5.64)分]、ITS分[(64.83±10.25)分]及TSBI分[(26.76±6.38)分]均显著低于对照组[分别为(28.67±8.53)分,(76.14±13.46)分,(39.65±12.74)分](P<0.01),且TSBI分与SCL-90各因子分和SAD分之间呈负相关,与ITS分及SES分之间呈正相关.结论儿童期虐待经历可对中专学生的心理健康和社交功能造成不良影响,有受虐待史的学生具有低自尊、低人际信任度、高社交焦虑和回避的特征。

Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and awareness of benefits and risks are all important.
Abstract: 目的 探讨品行障碍(CD)与5-羟色胺转运体基因遗传多态性的关系.方法对88例CD患者(病例组)和60例正常对照组提取基因组DNA,采用RFLP技术分析相应的基因型,并比较2组不同基因型的行为特点有无差异.结果 CD患者的5-羟色胺转运体基因多态性基因型L/L频率(43.2%)较正常对照组(26.7%)明显为多,且差异在儿童起病型中明显(P<0.05);伴有ADHD的CD患儿基因型L/L的频率(44.0%)较正常对照组(24.1%)显著为高,两者存在关联,基因型为S/S的CD患儿血浆5-HT水平[(0.85±0.32)μml/L]显著低于S/L和L/L基因型患者[(1.14±0.52)μml/L](P<0.05).结论5-羟色胺转运体基因多态性基因型L/L频率较正常对照组显著为高,等位基因L的个体5-HT活性较低,提示其与CD有一定关联,可能是CD的易感基因。

Journal ArticleDOI
TL;DR: Familiarity, ease of access, trust, and confidence will all be important for this project to succeed.
Abstract: 目的 评价D型人格量表中文版的信度和效度.方法 将D型人格量表译成中文,并回译.205例情绪障碍儿童和少年,正常儿童和少年组156名完成D型人格量表,EPQ人格问卷测评.结果 D型人格量表中文版内部一致性α系数0.88,重测信度0.76,分半信度系数为0.82;探索性因素分析证实了两个主要因子:消极情感和社会抑制(特征值大于1,累计贡献率为53.65%);负荷量≥0.4的共有13个条目,结构效度、效标效度和实证效度好.总量表与艾森克E、N分量表相关系数分别为-0.55和0.56,相关具有显著性(P<0.01).结论 该量表中文版经初步测试,信度、效度符合要求,可用于儿童和少年情绪障碍的人格测查。

Journal Article
TL;DR: Zhang et al. as mentioned in this paper investigated the effect of Shen-wu capsule and Tetrahydroxystilbene glucoside (TSG) on the learning-memory ability of AD-like mice.
Abstract: ObjectiveTo investigate learning-memory deficit in the different age of AD-like animal model and the protective effect of Shen-wu capsule and its effective component-2,3,5,4'-tetrahydroxy stilbene-2- O-β-D-glucoside(TSG) on learning-memory ability. MethodsAD-like APP V717I transgenic(Tg) mouse was observed from 4 to 16 months old. The Tg mice were randomly divided into 3 model groups(4 months 10 months and 16 months old), Shen-wu capsule group and TSG group. The animals were administered intragastrically by the drugs from 4 to 10 months old. For un-treated 10 months APP Tg mice, TSG were administrated to them from 10 to 16 months old. Control adapted the same age and background C57BL/6J mice. Learning-memory ability was detected by Morris water maze(MWM) and object recognition test(ORT). ResultsFor 4 month old APP Tg mice, learning-memory deficit appeared. The swimming time and distance increased in MWM and the discrimination index decreased in ORT. For 10 months old APP Tg mice, learning-memory deficit aggravated. Both Shen-wu capsule and TSG could decrease the swimming time in MWM and increase the discrimination index in ORT.For 16 month old APP Tg mice, learning-memory deficit still exist but abated a lot. TSG could improve learning-memory ability both in MWM and ORT. ConclusionAPP Tg mice from young to old mimic the learning-memory deficit in early, middle and late stage of AD. APP transgenic mice in 10 month old shows most significant learning-memory deficit and is most suitable to be used in the study for the pathology of Alzheimer’s disease and pharmacological mechanism of drugs on AD therapy. Shen-wu capsule and Tetrahydroxystilbene glucoside not only prevent the learning-memory deficit in early stage of AD-like model but also reverse the learning-memory deficit in late stage of AD-like model, so they would be applied in the treatment for AD and other neurodegenerative diseases.

Journal Article
TL;DR: Investigating the risk factors of chronic fatigue syndrome in doctors and nurses and studying the relationship between CFS and psycho-sociological factors, finding its risking factors highly related to psycho-Sociological status.
Abstract: Objective To investigate the risk factors of chronic fatigue syndrome (CFS) in doctors and nurses, and studying the relationship between CFS and psycho-sociological factors. Methods By applying the case-control study method in epidemiology, CFS are rated and their psycho-sociological factors are surveyed according to Symptom Checklist 90,Cattell 16 Personality Factors Questionnaire, Life Event Scale and Coping Strategy. Results 14 of 39 factors under the study significantly associated with CFS, in which, and 11 factors were risk the other 3 were protective factors. The risk factors included emergency(or=4.50), medicine(or=2.44), nurse (or=1.86), age (or=1.40), Personality B(or=4.61),L(or=3.44), G(or=1.75), positive life event(or=1.58),retreat(or=1.52) and self-abuse(or=1.43). Conclusion CFS of doctors and nurses should take more attention,and its risking factors highly related to psycho-sociological status.

Journal Article
TL;DR: Aripiprazole is effective and safe in the treatment of hyperprolactinemia by antipsychotics origin and the total preva- lence of side effects was similar in both groups.
Abstract: Objective To explore the efficacy and tolerability of aripiprazole in the treatment of hyperpro- lactinemia by antipsychotics origin.Methods 60 schizophrenic patients with hyperprolaetinemia by antipsychotics origin were randomly assigned to aripiprazole group(n=30)and placebo group(n=30)for 6 weeks,while re- ceiving original antipsychotics treatment.The prolactin(PRL)was measured at the baseline and end of study, same as the clinical symptoms of hyperprolactinemia were evaluated.The adverse effects on original antipsychotics treatment and other side effects were assessed with the Brief Psychiatric Rating Scale(BPRS)and the Treatment E- mergent Symptom Scale(TESS)before and after the study.Results The concentration of PRL was lower after the study [(27.5±8.2 )μg·L~(-1)]than before the study [(148.7±45.5)μg·L~(-1)]in aripiprazole group,and the difference was statistically significant(P<0.001),however this difference in placebo group was not statistical- ly significant before and after the study(P>0.05).Disappearment of amenia(27/28)and spontaneous lactation (16/16)were observed in aripiprazole group,while not any change occurred in placebo group.No adverse effects on original antipsychotics treatment were recorded in any group.Other side effects were mild and the total preva- lence of side effects was similar in both groups.Conclusions Aripiprazole is effective and safe in the treatment of hyperprolactinemia by antipsychotics origin.

Journal Article
TL;DR: Li et al. as discussed by the authors explored the demographic features on domestic violence in Hunan and found that individuals in the 30 to 39 age group were most highly represented in both the perpetrator and victim groups (40.3% and 27.1%, respectively).
Abstract: ObjectiveTo explore the demographic features on domestic violence in Hunan. MethodsThree hundred households with a history of domestic violence (DV) were randomly selected, and compared to control group of 300 non-DV households matched for family structure. A self-designed DV questionnaire was used.A total of 934 people were interviewed for the present study. Results(1) Individuals in the 30 to 39 age group were most highly represented in both the perpetrator and victim groups (40.3% and 27.1%, respectively). (2) 70.1% of perpetrators were men and 67.0% of victims were women; men were 5 times more likely to be perpetrators than women. (3) The education level of adult perpetrators was significantly higher than that of victims (8.9±4.7 vs. 7.5±5.2 years, P0.01), but significantly lower than that of controls(P0.05). The modal level of education was elementary school for both perpetrator and victim groups (32.2% and 43.1%, respectively). (4) While the differences were not significant between families with and without a history of DV with regard to actual annual income and living condition, self-estimated annual income and self-estimated living condition reported by DV families members were significantly worse than those reported by non-DV families. Income and the proportion contributed to total family income were significantly higher in perpetrators than in victims[477.5±489.1 vs. 709.7±796.4 yuan, P0.01, and (24.1±32.2)% vs (17.3±26.0)%, P0.01], but lower than in control(P0.05 or P0.01).Male,self-estimated lower economic status and lower contributions to the total family income were risk factors for DV. ConclusionIndividuals in the 30 to 39 age group are at higher risk for DV. The perpetrators are more likely to be men, and victims are more likely to be women. Both perpetrators and victims report significantly lower education level and lower income. Individuals who earn a lower proportion of the family total income are more likely to be victims.

Journal ArticleDOI
蔺华利, 施旺红, 王军辉, 李亚娟, 程淑亮 
TL;DR: Familiarity, ease of access, trust, and awareness of benefits, will all be important.
Abstract: 目的 探讨阿立哌唑和氯丙嗪对首发精神分裂症患者认知功能的影响.方法84例首发精神分裂症患者随机均分为阿立哌唑组和氯丙嗪组,在治疗前和治疗12周后作数字广度(顺、逆)、即刻逻辑记忆、延迟逻辑记忆、即刻视觉记忆、延迟视觉记忆、连线测验A和B、字色混淆测验(Stroop)以及威斯康星卡片分类测验(WCST)等神经心理测验.结果治疗第12周末后,阿立哌唑组除视觉记忆外其他各项认知功能指标均有所好转(P<0.05 orP<0.01),而氯丙嗪组在13项认知功能指标中有5项恶化,主要在逻辑记忆和执行功能方面;阿立哌唑组除视觉记忆外各项认知功能测查结果均明显好于氯丙嗪组[阿立哌唑组和氯丙嗪组即刻逻辑记忆分别为(13.98±3.24)分和(5.01±3.98)分,完成连线测验B的时间分别为(90.45±37.16)s和(129.25±36.2)s,WCST持续性错误数分别为(2.56±3.82)个和(11.13±9.87)个等,P<0.05或P<0.01].结论阿立哌唑对首发精神分裂症患者的认知功能有改善作用,而氯丙嗪对认知功能的某些领域有损害。

Journal ArticleDOI
TL;DR: DAS评分入院时分别为(17.8±3.7)分和(16.0±8.1)前后评估临床疗效及亲属的心身健康状况,
Abstract: 目的 评估系统家庭治疗对精神分裂症患者的综合治疗效果和对照料者心身健康的影响.方法 采用随机抽样的方法,将150例精神分裂症患者分为治疗组和对照组,在2组均使用抗精神病药物治疗的基础上,仅对治疗组辅以系统家庭治疗,治疗前后评估临床疗效及亲属的心身健康状况.结果 在随访1年末,治疗组和对照组年复发率分别为19.0%和35.4%(P<0.05),随访2年末分别为15.9%和33.8%(P<0.05).治疗组出院时和随访30个月末PANSS评分分别为(60.5±7.8)分和(46.8±8.1)分(P<0.01),对照组分别为(57.5±8.6)分和(57.0±8.0)分(P>0.05).治疗组和对照组DAS评分入院时分别为(17.8±3.7)分和(16.8±8.1)分(P>0.05),出院时分别为(8.1±2.7)分和(9.3±2.9)分(P<0.05),随访30个月末分别为(6.7±4.9)分和(14.5±8.3)分(P>0.01).治疗组治疗前和随访30个月末GHQ评分分别为(4.8±4.1)分和(3.1±2.6)分(P<0.01).结论 系统家庭治疗可以降低精神分裂症患者的复发率,减轻其精神症状和社会功能残疾程度,并在一定程度上改善照料者心身健康状况。

Journal Article
TL;DR: The PRCA shows acceptable reliability and validity as a self-report measure for childhood abuse experience in china.
Abstract: ObjectiveTo development a personal report of childhood abuse(PRCA),and to study the reliability and validity of the PRCA. MethodsThe samples of 179 primary school students were investigated by applying Personal Report of Childhood Abuse. We examined the internal reliability, test-retest reliability and the validity of PRCA. ResultsThe Cronbach's α coefficient of PRCA was 0.87; physical abuse factors was 0.85; emotional abuse factor was 0.73; sexual abuse was 0.99; neglect factors was 0.89.The test-retest reliability coefficient of PRCA was 0.68; physical abuse factors was 0.46; emotional abuse factors was 0.56; sexual abuse factors was 0.70; neglect factors was 0.54. The correlation coefficient among every factors of PRCA ranges from 0.24 to 0.77.SDS scales were significantly related to the physical abuse, emotional abuse, sexual abuse, neglect and PRCA (r=0.35~0.77,P0.01). Compared with no-abused students, the students who had been abused in childhood had significantly high total and factor scores of SCL-90(total:1.84±0.61 vs 1.59±0.57,t=2.84,P0.01).The scores of PRCA of male student was higher than female’s(total:12.87±16.46vs8.49±12.31,t=2.00,P0.05;frequency: 1.72±1.71 vs1.16±1.16,t=2.53,P0.05). Abuse behaviors emerge mostly first time before 10 years old.ConclusionThe PRCA shows acceptable reliability and validity as a self-report measure for childhood abuse experience in china.

Journal Article
TL;DR: In this paper, the authors study the relationship between aggressive behavior and rearing pattern, family environment and self-concept, and find that appropriate family cohesion and parental rearing patterns are helpful to prevent the aggressive behavior in children.
Abstract: Objective To study the relationship between aggressive behavior and rearing pattern,family environment and self-concept.Methods 181 pupils in sixth grade in primary school were assessed by CBCL、EMBU、FES-CV、Piers-Harris child self-concept scale.Results In male aggression negatively correlated to moral- religions emphasis,happiness satisfaction,positively correlated to warm feeling,understanding,rejection.In fe- male,aggression negatively correlated to cohesion,warm feeling and understanding,positively correlated to pun- ishment.Multiple regression analysis indicate that aggression was predicted by warm feeling,understanding,rejec- tion,happiness and satisfaction in male; and predicted by cohesion,warm feeling and understanding in female. Conclusion Appropriate family cohesion and parental rearing pattern,positive self-concept are helpful to prevent the aggressive behavior in children.