Showing papers in "Clinica Chimica Acta in 1997"

TL;DR: The results by this method agree very well with those obtained by electrophoresis and salt fractionation and the method is simple, it has excellent precision and the reagents are stable.

TL;DR: Polyenylphosphatidylcholine (PPC) fully prevents ethanol-induced septal fibrosis and cirrhosis, opposes ethanol- induced hepatic phospholipid depletion, decreased phosphatidylethanolamine methyltransferase activity and activation of hepatic lipocytes, whereas its dilinoleoyl species increases collagenase activity.

TL;DR: A new method for the determination of the total iron-binding capacity of serum is described, based on the fact that Fe+++ is adsorbed on magnesium carbonate, while iron combined with siderophilin is not.

TL;DR: The development of accurate and precise methods for urinary albumin has provided a tool to physicians to extend the length and improve the quality of life of many diabetic individuals.

TL;DR: The aim of this report is to define standard conditions for this analytical technique and to calculate confidence intervals for the major metabolites in normal urine samples, such as preliminary and mandatory stages for clinical diagnostic 1H NMR utilization.

TL;DR: Since 1957 the introduction of the assay for serum ferritin has made it possible to assess the levels of storage iron in normal subjects and assays for free erythrocyte protoporphyrin and the circulating transferrin receptor methods to evaluate iron supply for erythropoiesis.

TL;DR: In this paper, the authors describe genetic defects that occur in the UGT1 gene complex that cause three non-haemolytic unconjugated hyperbilirubinaemia syndromes.

TL;DR: The data indicate that the intra-erythrocyte environment of high glycators favours glycation of haemoglobin, which could have important consequences for diabetic patients in terms of monitoring their glycaemic control and in the progression of those complications related to non-enzymic Glycation of intracellular proteins.

TL;DR: G glycogen phosphorylase isoenzyme BB is a promising enzyme for the early detection of ischemic myocardial damage and should be restricted at present to clinical settings that really require their high specificity.

TL;DR: GPI anchors can act as intracellular targeting signals, in transmembrane signalling, in the clathrin-independent endocytic process of potocytosis and as hormone mediators, and can confer additional properties on enzymes that may be important in their physiological and pathophysiological functioning.

TL;DR: The chymostatin-sensitive angiotensin II-generating enzyme in human vascular tissues is identified as chymase, identical to the sequence for human skin/heart chymases.

TL;DR: In this article, thermal mud therapy is shown to influence chondrocyte activity of osteoarthrosic patients by modulating the production of serum cytokines, such as interleukin 1, and this was related to the presence of an anti-inflammatory principle in mature thermal mud.

TL;DR: The finding that plasma changes in MDA are reflected in urine 24 h later validates the use of urinary MDA as a marker of whole body lipid peroxidation in populations without renal disease.

TL;DR: Differences in the mechanisms of liver damage and of viral clearance in hepatitis C in comparison to hepatitis B, reflected in these patients by the levels of circulating cytokines, may be mirrored by differences in their blood lipid composition.

TL;DR: During blood storage, glutathione-dependent antioxidant systems in erythrocytes and antioxidant defence in plasma are depleted, and from the present study, a twelve-day period can be considered a safe storage limit.

TL;DR: The results indicate an imbalance between radical production and destruction in favour of prooxidant conditions in the young rats and the induction by hypercholesterolemic diet of the antioxidative response in erythrocytes.

TL;DR: Current limitations in the definition, diagnosis and classification of alcoholism, the confounding influences of race and gender on association studies, as well as the statistical approach of linkage studies are discussed as they relate to the endeavor to uncover valid genetic markers for the risk of alcoholism.

TL;DR: In this article, a reagent and assay conditions for the determination of the catalytic concentration of α-amylase (E.C. 3.1) in serum with 2-chloro-4-nitrophenyl-α- d -maltotrioside as substrate are described.

TL;DR: The method presented here is accurate and reliable for measurement of glutamine synthetase activity in muscles and correlated well with a radiometric assay.

TL;DR: New ELISA with recombinant SP-D and F(ab')2 fragment of anti-SP-D monoclonal antibody gives a greater advantage for the accurate detection of SP- D in sera from patients with idiopathic pulmonary fibrosis, interstitial pneumonia with collagen disease and pulmonary alveolar proteinosis without interference of rheumatoid factor.

TL;DR: The results suggest that the significant decline in circulating alpha-tocopherol and coenzyme Q10 concentrations was mainly a function of the decrease in serum total cholesterol concentrations, indicating that LDL from the former group may be more vulnerable to free radical-mediated damage and lipid peroxidation.

TL;DR: First results of the HPLC-ER method, when applied to body fluids and food analysis, are presented, which were statistically equivalent to those obtained by enzymatic kits.

TL;DR: The results showed that only prolonged storage time at high temperatures could cause significant decreases in urine creatinine levels, and concluded that in all but extreme cases urine Creatinine is virtually unaffected by storage time and temperature.

TL;DR: C-erbB-2/neu, EGFR, histological grade, pN, pT and ER were subjected to a Cox multivariate regression analysis: neu was the most important parameter in predicting recurrence, and EGFR was a significant predictor for OS.

TL;DR: The results suggest that synovial fluid concentration of hyaluronan is appropriate as a prognostic value in the evaluation of different kinds of joint diseases.

TL;DR: The correlation measurements show that the thermal biosensor calibrated with aqueous glucose standards generally gives lower values on blood glucose than the reference methods calibrated for serum or blood measurements.

TL;DR: The concentration of MDA by the thiobarbituric acid assay in untreated serum may not reflect free radical damage to lipoproteins, and there was no evidence of increased lipoprotein oxidation using 7-ketocholesterol in NIDDM or PVD.

TL;DR: The structure of this domain and ways in which it may be cleaved by chemical and enzymatic means provide a basis for understanding the solubilization of alkaline phosphatase from tissues in vitro and in vivo and the generation of isoforms.

TL;DR: In this paper, the authors compared the efficiency of various biochemical parameters to the traditional criteria of Light et al. for differentiating exudates from transudates in the diagnosis of pleural effusions.

TL;DR: The electrophoretic mobilities of catalase in erythrocytes of hypocatalasemic patients were indistinguishable from that of healthy controls.