Showing papers in "Clinical Neurophysiology in 2018"

TL;DR: The goal is to summarize the scientific evidence for the utility of EEG when diagnosing and monitoring PWE and address specific pathophysiological conditions of the brain that produce epilepsy.

TL;DR: The main principles of magnetoencephalography (MEG) and the value of combined MEG and EEG are discussed and some potential future clinical applications of MEG are reviewed.

TL;DR: Deep neural networks can accurately detect epileptiform discharges from scalp EEG recordings and may result in a fundamental shift in clinical EEG analysis.

TL;DR: The results suggest that α2a adrenergic agonists may be developed as a new class of sleep enhancing medications with neurocognitive sparing benefits and Pharmacological induction of biomimetic N3 sleep with psychomotor sparing benefits is feasible.

TL;DR: Future developments should be based on full understanding of the neurophysiological concepts underlying the MUNE calculation, in order to find a quick, well-tolerated, operator-friendly and reliable method to apply more universally in clinical practice.

TL;DR: DTAABR and alpha RP are the best qEEG indices and superior to ASPECTS in post-stroke outcome prediction, and improve the discriminative capacity of already known clinical and imaging stroke outcome predictors.

TL;DR: It is suggested that EEG responses to novel events in this rapid, simple, and inexpensive test have tremendous promise for tracking individual trajectories of cognitive dysfunction in Parkinson's disease.

TL;DR: It is argued that the pathophysiology of GBS is dynamic and that serial studies allow a more accurate diagnosis of subtypes and that Uncini's or Rajabally's criteria sets can be employed for an indicative subtype diagnosis.

TL;DR: It is found that experts use ultrasonography often for inflammatory, hereditary, traumatic, compressive and neoplastic neuropathies, and somewhat less often for neuronopathies and myopathies.

TL;DR: A single-EEG-sensor ASSC technique based on the dynamic reconfiguration of different aspects of cross-frequency coupling estimated between predefined frequency pairs over 5 s epoch lengths makes the entire methodology appropriate for longitudinal monitoring using wearable EEG in real-world and laboratory-oriented environments.

TL;DR: The ability to identify who, of those with RBD, is at high risk for later neurodegenerative disorders will be paramount, and would in addition advance the understanding of the prodromal stages of the alpha-synucleinopathies.

TL;DR: It is established that interictal fast ripples (FR) are detectable on scalp EEG, and may potentially serve as a biomarker of epilepsy in children with TSC and investigated their association to epilepsy.

TL;DR: A novel automatic pipeline for pre-processing and artifact rejection of EEG data is proposed, which innovates relative to existing methods by not only following state-of-the-art guidelines but also further employing robust statistics.

TL;DR: Automated ESI has an accuracy similar to previously reported neuroimaging methods and will contribute to increased utilization of source imaging in the presurgical evaluation of patients with epilepsy.

TL;DR: MUNIX revealed generally good reliability, but was rater dependent and ongoing support for raters was needed, and can be implemented in large clinical trials as an outcome measure after training and a qualification process.

TL;DR: It is hypothesised that increasing contralesional excitability with anodal transcranial direct current stimulation (a-tDCS) would benefit motor performance in patients with moderate-severe impairment.

TL;DR: This is the first work to show how brain-scalp distance and cerebrospinal fluid thickness influence focality, and to show the disassociation between dorsal and medial TMS.

TL;DR: These findings unveil similar abnormalities in functional cortical connectivity estimated in widespread alpha sources in ADMCI and PDMCI, true at both group and individual levels.

TL;DR: A replicable randomization of the brain network is found in MDDs, characterized by more homogeneous degree distribution, greater resilience and lower rich-club coefficient, reflecting the reconfiguration of thebrain network caused by the reduction of hub nodes in MDD.

TL;DR: The demonstration of either ancillary finding, electro-cortical inactivity or, preferably, cerebral circulatory arrest, is mandatory for diagnosing BD in patients with a primary infratentorial brain lesion in cases of isolated brainstem lesion.

TL;DR: The results indicate that tVNS is selectively affecting the GABAergic system in the motor system contralateral to the stimulated ear as reflected in a behavioral and electrophysiological modulation.

TL;DR: The existence of persistent inward currents in spinal motoneurones and the evidence that the channels involved may be upregulated following central motor lesions are discussed.

TL;DR: Transferable learning classifier can detect patients at risk of developing central neuropathic pain by comparing them with patients who had already developed pain and with able bodied controls.

TL;DR: Higher burden of EAs in patients with aneurysmal subarachnoid hemorrhage independently predicts worse outcome and may serve as a target for prospective interventional controlled studies to directly assess the impact of AEDs, and create evidence-based treatment protocols.

TL;DR: Time to epileptiform activity and background recovery are independent prognostic indicators in comatose patients after cardiac arrest and are highly associated with outcome and levels of neuron-specific enolase.

TL;DR: In this article, the authors investigated for quantitative EEG (QEEG) differences between Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) patients and healthy controls, and for QEEG signatures of cognitive fluctuations (CFs) in DLB.

TL;DR: There is a significant difference in autonomic function in patients with relapsing remitting multiple sclerosis and progressive MS; with pwPMS having a higher burden of AD, which is particularly evident for sweating dysfunction.

TL;DR: Applying automated HFO methods to intraoperative electrocorticography recordings results in false positive fast ripple detections, which predict non-seizure free post-operative outcome if found in an unresected site.

TL;DR: The advantages of ECoG-based language mapping over the gold-standard stimulation include: (i) lack of stimulation-induced seizures, (ii) better sensitivity of localization of language areas in young children, and (iii) shorter patient participant time.

TL;DR: It is demonstrated that ctDCS results in short-term improvement of postural adaptation in healthy individuals and future studies need to investigate if multisession tDCS combined with training or rehabilitation interventions can induce prolonged improvement ofPostural balance.