Showing papers in "Clinics in 2006"
••
TL;DR: An adipocyte-endothelium interaction might be an important mechanism of inflammation and vascular dysfunction in obese subjects with metabolic syndrome and lean controls.
112 citations
••
TL;DR: The immunomodulatory properties of sex hormones/receptor antagonists/sex steroid synthesizing enzymes following trauma-hemorrhage suggests novel therapeutic strategies for the treatment of immunodepression in surgical patients.
105 citations
••
TL;DR: The aim of this report is to review syphilis-related oral lesions, as well as to summarize the relations between human immunodeficiency virus (HIV) and syphilis.
101 citations
••
TL;DR: This study aimed to assess the frequency of drug-drug interactions in prescriptions and their potential clinical significance in patients of a Brazilian teaching hospital and found patients did suffer adverse drug reactions from major drug- drug interactions.
97 citations
••
TL;DR: The number of working hours was the only variable associated with occurrence of low backPain, with an average of about 1 hour longer work time for drivers with low back pain compared to those without it and with an odds ratio of 1.07.
94 citations
••
TL;DR: In this paper, the authors present a review of complex wound cases and suggest that complex wound should be treated by multidisciplinary teams in specialized hospital centers, either chronic or acute.
92 citations
••
TL;DR: Digital values can resolve disagreement among different observers about the quality of staining intensity because the digital method provides a numerical value for each individual case; thus, it increases the diagnostic and, more importantly, the prognostic sensitivity of the immunohistochemical analysis.
87 citations
••
TL;DR: The modified Charles procedure for the treatment of penoscrotal lymphedema is easily reproducible and allows better local hygiene, easier ambulation, voiding in the standing position, resuming sexual intercourse, and finally, better cosmetic results in the affected area with remarkable improvement in quality of life.
68 citations
••
TL;DR: The evolution of hip fracture in the year following it is related to high mortality and to a decrease in functional ability, with age and male sex being the factors associated with a worse prognosis, emphasizing the need for special follow-up care of these groups during the immediate and late postoperative periods.
68 citations
••
TL;DR: The risk for postoperative undernutrition was evidenced up to 1 year, while spontaneous improvement in food intake was slow and inefficient, and specific protocols should be devised to improve nutrition and health during the postoperative phase until successful dietary adaptation is achieved.
58 citations
••
TL;DR: The association of tumor-infiltrating CD4(+) T lymphocytes with lymph node metastasis suggests a role for these cells in the spread of neoplasia to lymph nodes in patients with early breast cancer.
••
TL;DR: The large impact of RET proto-oncogene analysis on the clinical management of MEN2 and the role of early RET molecular DNA diagnosis in providing clinicians and surgeons with valuable information that enables them to indicate early total thyroidectomy are discussed.
••
TL;DR: Protein S-100B had a very high sensitivity and negative predictive value and could have an important role in ruling out the need for cranial computed tomography scan after minor head injury, particularly in countries where trauma incidence is high and medical resources are limited.
••
TL;DR: Although evolutive standard base excess and serum lactate level are still outcome markers in severe sepsis and septic shock patients resuscitated with early goal-directed therapy, other studies must be performed to clarify if hemodynamic interventions based on standard baseExcess and lactateLevel could be reliable to improve clinical outcomes in severeSevere sepsic shock patients.
••
TL;DR: Cognitive and functional deficits had a significant association with delirium, although only cognitive deficit was revealed to be an independent risk factor after analysis with the logistic regression model.
••
TL;DR: The molecular analysis reinforced the hypothesis that the transmission of Cryptosporidium hominis during the period the samples were collected occurred in an outbreak pattern, possibly by person-to-person contact through the fecal-oral route.
••
TL;DR: The role of selectins and nitric oxide in experimental and clinical sepsis as well as the therapeutic outcomes of blocking therapies are described.
••
TL;DR: It is concluded that single-stage feminizing genitoplasty consisting of vulvoplasty, clitoroplasty and Y-V perineal flap produced good cosmetic and functional results in virilized girls with congenital adrenal hyperplasia, with few complications.
••
TL;DR: The high iodine intake that was present from 1998 through 2005 may be related to a higher prevalence of chronic autoimmune thyroiditis in both areas that were studied.
••
TL;DR: There is a need for prevention of primary (congenital infections), secondary (Congenital glaucoma and retinopathy of prematurity), and tertiary (congentital cataract) visual impairment and the prescription of optical aids for school-age children will help them perform better at school and contribute to their social inclusion.
••
TL;DR: It is indicated that patients with metastatic prostate cancer have higher plasma vascular endothelial growth factor levels than patients with localized disease or in healthy controls.
••
TL;DR: Perinatal mortality was very high in prenatally diagnosed cases of congenital diaphragmatic hernia, and mortality is related to the presence of herniated liver, right-sided lesion, and major mediastinal shift.
••
TL;DR: A comparison of the two drugs showed that the degree of articular stiffness was significantly lower with diacerein, although degenerative changes were similar, and the prophylactic chondroprotective effects of diACErein and glucosamine are histologically similar.
••
TL;DR: Final analysis revealed a granulosa cell tumor with oval nuclei having a longitu-dinal nuclear groove (coffee bean appearance),focal invasion of the tunica albuginea and rete testis, nomitotic figures, and no invasion of surgical margins, sper-matic cord, or epididymis.
••
TL;DR: Patients undergoing osteosynthesis, with a less morbid surgical technique and earlier rehabilitation, had longer survival times than patients who received endoprostheses, and the only significant predictor was the type of surgery employed.
••
TL;DR: Physiotherapy produced significant improvement in articular range of motion, muscular strength, and articular dysfunction in patients with Legg-Calvé-Perthes disease, but these improvements were not evident on radiographs.
••
TL;DR: A 65-year-old white woman, in treatment for diabetesmellitus and hyperthyroidism for years, complained offlare-ups of erosions on the oral mucosa, explained by the use of dentures, and was placed on steroid therapy, an-tibiotics, and volume and electrolytic replacement, which controlled her condition.
••
TL;DR: Light microscopic examination of hair shafts of patients with Chédiak-Higashi or Griscelli-Prunieras syndrome reveals subtle differences that are useful in identifying both disorders, but not in distinguishing between them.
••
TL;DR: By detecting deficiencies in the balance of flexor and extensor muscles (a balance that is required for uniform gait), it will be possible to select specific rehabilitation exercises according to the individual needs of each patient undergoing surgery.
••
TL;DR: That carcinoid tumors of themajor duodenal papilla have been described more fre-quently than those of the minor papilla is probably because of the fact that they often give rise to symp-toms (for example jaundice and pain) that demand inten-sive examination or surgery; while those of-pilla are frequently asymptomatic.