Showing papers in "Colloids and Surfaces B: Biointerfaces in 2014"

TL;DR: The FTIR study reveals that diverse biomolecules viz. carboxyl group, primary and secondary amines, amide I, II, and III bands etc serve as a tool for bioreduction and capping agents there by offering stability to particles by preventing agglomeration and growth.

TL;DR: This work provides the first direct evidence that GO-Ag nanocomposites can inhibit the growth of microbial adhered cells, thus preventing the process of biofilm formation, and support the idea thatGO-Ag Nanocomposite may be applied as antibacterial coatings material to prevent the development of biofilms in food packaging and medical devices.

TL;DR: The rapidly increasing knowledge of the many overexpressed biochemical makers in pathological sites has enabled the development of liposomes decorated with ligands for cell-surface receptors and active delivery, resulting in an optimal therapeutic effect devoid of side effects.

TL;DR: Appropriate use of surface texturing and chemical patterning methodologies allow for reduction of both blood coagulation and platelet adhesion, and new methods of surface interrogation at high resolution allow for measurement of the relevant biological factors.

TL;DR: In vitro toxicity data suggest that the DOX-GQD-FA nanoassembly can target HeLa cells differentially and efficiently while exhibiting significantly reduced cytotoxicity to non-target cells.

TL;DR: The study showed that treatment with NPs is notably effective against the proliferation of HepG2 and MCF-7 cancer cells in a dose-dependent manner, and upregulation of the mRNA expression level of Bax, p53, and caspase-3 and the down regulation of the anti-apoptotic gene Bcl-2 is demonstrated.

TL;DR: The results are indicative of the potential of the strain for the development of ex situ microbial enhanced oil recovery processes using glucose or date molasses based minimal media and the biosurfactants were stable over wide range of pH, salinity and temperatures.

TL;DR: This study focuses on synthesis of silver-zinc oxide (Ag-ZnO) nanocomposites which will have a broad-spectrum antibacterial activity against Gram-positive and Gram-negative bacteria.

TL;DR: The efficiency of green synthesized AgNPs was studied with the help of fluorescence activated cell sorting (FACS) and was shown to induce apoptosis through reactive oxygen species (ROS) generation in HeLa cells.

TL;DR: The developed formulations did not show any toxicity and were safe for intranasal delivery for brain targeting and in vitro diffusion studies revealed that nanoemulsions had a significantly higher release compared to drug solution.

TL;DR: Oil-in-water nanoemulsion was formulated using sesame oil, non-ionic surfactant (Tween20/Tween80) and water by ultrasound cavitation method and exhibited antibacterial activity against Staphylococcus aureus and Eugenol-loaded Nanoemulsion S3E3 exhibited antib bacterial activity against S. aureUS.

TL;DR: The content of zinc implanted in titanium can easily be controlled within the safe concentration using plasma immersion ion implantation technology, indicating that the Zn-implanted titanium with excellent osteogenic activity and partly antibacterial effect can serve as useful candidates for orthopedic and dental implants.

TL;DR: Alginate/cashew gum nanoparticles were prepared via spray-drying, aiming at the development of a biopolymer blend for encapsulation of an essential oil, and Kinetic studies revealed that release pattern follow a Korsmeyer-Peppas mechanism.

TL;DR: The prepared gel exhibited sustained ex vivo permeation of aceclofenac over 8h through excised mouse skin, and in vivo anti-inflammatory activity in carrageenean-induced rats demonstrated comparative higher inhibition of swelling of rat paw edema by the prepared gel compared with that of the marketed acecl ofenac gel over 4 h.

TL;DR: In vitro and in vivo, the pre-administration of functionalized AgNPs reduced the edema and cytokines levels in the paw tissues, early after the induction of inflammation, demonstrating the possible use of synthesizedAgNPs for the treatment of psoriasis lesions.

TL;DR: Q-NLC dramatically enhanced the anti-cancer activities of Q, which were associated with enhanced Q solubility and stability, and increased Q content in those cancer cells.

TL;DR: Go has a great potential to be a promising drug-binding effector for hydrogel functionalization in drug delivery and could be effectively controlled in the controlled release of drugs.

TL;DR: The release study of NAP in buffer solution elucidate that the PCL/NAP-βCD-IC nanofibers have higher release amount of N AP than thePCL/ NAP nanof fibrous matrix due to the solubility enhancement of Nap by CD-IC.

TL;DR: The implications of changes in the properties of nanoparticles and endogenous biomolecules at the nano-plasma interface including toxicity, immunological recognition, molecular targeting, biodistribution, intracellular uptake, and drug release are reviewed.

TL;DR: It is suggested that pectin coated liposomes, especially the LMP-L, could be a promising transdermal drug delivery system with better storage stability and skin permeation.

TL;DR: The future panorama of polymerized cyclodextrins is quite bright as they can serve as useful multifunctional tools for pharmaceutical scientists to develop and optimize drug delivery through various routes.

TL;DR: The various preparation methods of these nanoparticles and the impact of critical parameters such as molecular weight, charge or choice of stabilizer will be described, as these control the overall mean size and surface of the nanoparticle which is a critical factor for drug delivery.

TL;DR: The protein corona could significantly reduce the burst effect of either protein conjugated nanocarriers or carriers with surface loaded drug (i.e., SPIONs), and the corona shell only slightly changed the release profile of polymeric nanocapsules.

TL;DR: The direct electrochemistry of glucose oxidase (GOx) was successfully realized on electrochemically reduced graphene oxide and silver nanoparticles (RGO/Ag) nanocomposite modified electrode, and the fabricated biosensor showed an acceptable sensitivity and selectivity for glucose.

TL;DR: The binding thermodynamic parameters delineate the predominant role of H-bonding and van der Waals forces between β-galactosidase and CuO NPs binding process and the result revealed that the complexation is enthalpy driven.

TL;DR: It is demonstrated that DDAB is a potent inducer of cell uptake and cell death in both cell lines and curcumin loaded liposomes indicate significant potential as delivery vehicles for the treatment of cervical cancers.

TL;DR: Novel niosomal formulations containing nutritional supplements such as gallic acid, ascorbic Acid, curcumin and quercetin as single agents and in combination are developed to evaluate the effect of the active molecules co-encapsulation on the physico-chemical properties of the carriers, on their antioxidant properties and capability of releasing the encapsulated materials.

TL;DR: The addition of gelatin to carrageenan is found to improve the thermal stability of the gelatin-carrageenan fibers in the composite hydrogels, and the tuning of pore size distribution for drug delivery applications using thermoporometry is feasible.

TL;DR: The results advocate potential of SLNs as a novel carrier for topical delivery of ADA in topical therapeutic approaches and open new avenues for drug delivery which better meets the need of anti-acne research.

TL;DR: The secretion of cysteine and proteins was found to play an important role in the formation and stabilization of CdS QDs and the changes to the functional groups on the biomass surface were investigated through Fourier transform infrared spectroscopy.