Showing papers in "Colloids and Surfaces B: Biointerfaces in 2015"

TL;DR: The most used materials for tissue engineering strategies are reported together with the main achievements, challenges and future needs for research and actual therapies and a compilation of the most relevant results and strategies are provided.

TL;DR: An overview of the most up-to-date information regarding the starch nanoparticles including the preparation processes and physicochemical characterization will be presented in this review.

TL;DR: The present review is an attempt to contemplate the studied nanocarriers in the field of anticancer drugs delivery, their advantages and disadvantages and future perspectives.

TL;DR: The antimicrobial studies showed that the copper nanoparticles had high activity against Gram-positive bacteria, standard and clinical strains, including methicillin-resistant Staphylococcus aureus, comparable to silver nanoparticles and some antibiotics.

TL;DR: By mimicking more closely the structure and composition of HM fat globules, this novel IMF concept with Nuturis(®) may have metabolic and digestive properties that are more similar to HM compared to Control IMF.

TL;DR: Results showed that the best blood-clotting index (BCI) was achieved in vitro by a chitosan/gelatin sponge (CG) ratio of 5/5 (W/W), and CG can be considered an effective absorbable hemostatic material.

TL;DR: Results revealed that the binding of serum albumins with chitosan nanoparticles induces a significant change in protein morphology and the shape of the polymer.

TL;DR: The novel CD44 targeted dendrimer based nanocarriers appear to be proficient in mediating site-specific delivery of CDF via CD44 receptors, with an improved therapeutic margin and safety.

TL;DR: The results suggest that the prepared chitosan-hyaluronic acid/VEGF loaded nanofibrin composite sponges (CHVFS) have potential to induce angiogenesis in wound healing.

TL;DR: Wide broad cells with various instruments approved that graphene oxide is promising material for nanomedicine in the near future.

TL;DR: Results indicate that multilayered liposomes properly coated with polyelectrolytes of HA and CH by electrostatic interaction improve stability and can also function as potential drug delivery system for the transdermal delivery of the hydrophobic antioxidant quercetin.

TL;DR: CS-NLC can be considered to be a safe and effective nanocarrier for nose-to-brain drug delivery; however, to obtain a higher concentration of the drug in the brain following intranasal administration, further modifications are warranted in the CS-N LC formulation.

TL;DR: It was found that under most conditions WPI NPs present good partial wetting properties, but that at the isoelectric point (pI) and high ionic strength the particles become more hydrophobic, resulting in less stable Pickering emulsion.

TL;DR: Salient features such as biocompatibility, controlled release, target competency, potential of penetration, improved physical stability, low cost and ease of scaling-up make SLNs viable alternative to liposomes for effective drug delivery.

TL;DR: Lf-mNLC is a promising drug delivery system for targeting therapy of brain disease and its effect on controlling the progression of Alzheimer's disease in rats was evaluated.

TL;DR: The results showed that dual-drug-loaded nanocarriers exhibited a superior cytotoxic effect than a cocktail combination at a lower dose and could serve as a promising therapeutic approach to improve clinical outcomes against various malignancies.

TL;DR: The results indicate that adequate engineering of PLGA NPs represents an enticing technological approach to harness novel antimicrobials for P. aeruginosa lung infection, such as CAMPs, especially in CF.

TL;DR: AIAgNPs showed a dose dependant anti-proliferative effect against COLO 205 and MDCK cells with an IC50 of 3 and 4 μg/mL and 100 and 75 μg/ mL, respectively after 24 and 48 h.

TL;DR: The evolution of liposomes from passive to active targeting and challenges in the development of targeted liposome for specific therapies are highlighted.

TL;DR: It is revealed that lentil legumin-like protein could form long-life foams at mild acidic and neutral pH and the potential for use of lentil protein as a novel foaming plant-based stabilizer is demonstrated in food and non-food applications where stable, long- life foams are required.

TL;DR: The proposed approach could overcome inherent problems associated with bacterial infections on Ti-based implants, simultaneously enabling the development of orthopedic implants with enhanced and synergistic antibacterial functionalities and bone cell promotion.

TL;DR: Clotrimazole-silver SLNs was found to be an efficient nanoantibiotic for enhanced and sustained antibacterial activity against susceptible and resistant Staphylococcus aureus and methicillin-resistant S. aUREus.

TL;DR: It is demonstrated that the surface morphology and roughness at the nanoscale level substantially affect the titanium dioxide surface-water droplet interaction, opposing to previous observations for microscale structured surfaces.

TL;DR: Amorphous curcumin nanosuspensions were fabricated using the antisolvent precipitation method with β-lactoglobulin (β-lg) as a stabilizer and showed maximum aqueous stability which was >90% after 30 days and solubility was enhanced ∼35-fold due to the reduced size and lower crystallinity.

TL;DR: These curcumin conjugated silver nanoparticles show anti-bacterial activity and can successfully determine nucleic acid (DNA and RNA) in the concentration range 100-1000 ng/mL with a linear regression coefficient >0.997 using Resonance Rayleigh Scattering spectra.

TL;DR: The synthesized nanoparticles found to be photoluminescent, highly stable and crystalline in nature having a zeta potential of -31 mV suggest that they find application as both antifungal agents and drug delivery vehicles.

TL;DR: Superhydrophobic anatase TNTs coating on SS surface offers the opportunity for the application of SS as a promising permanent biomaterial in blood contacting biomedical devices, where both reducing platelets adhesion/activation and improving corrosion resistance can be effectively combined.

TL;DR: Results suggest a continuous mucus layer exists throughout the small intestine, which is highly stratified adjacent to the epithelium, and correlates with stratified MUC2 staining.

TL;DR: An attempt has been made to develop polymeric mixed micelle delivery system using Poloxamer 407 and Pluronic P123 for the encapsulation of an antiretroviral drug, Nevirapine, which exhibits high entrapment efficiency along with sustained release of the drug.

TL;DR: The developed RGD peptide-targeted multifunctional dendrimers may be used as a versatile platform for targeted therapy of different types of αvβ3 integrin-overexpressing cancer cells and display specific therapeutic efficacy to the target cells.