Showing papers in "Colloids and Surfaces B: Biointerfaces in 2017"

TL;DR: This review focuses on fabrication techniques of PLGA based nanostructures and their advanced biomedical applications covering drug delivery and in-vivo imaging.

TL;DR: The results supported the advantages of employing a bio-green approach for developing silver nanoparticles with antimicrobial, antioxidant, and antiproliferative activities in a simple and cost- competitive manner.

TL;DR: This review provides a comprehensive compendium of recent advancements in culturing SCs using 2-D and 3-D techniques involving spheroids, biomaterials, and bioreactors.

TL;DR: Encouraging results suggest that Au@CB has a significant potential for the treatment of colon rectal cancer.

TL;DR: The literature is critically reviewed and convincing evidence is summarized which explore the pharmaceutical significance and therapeutic feasibility of the advanced delivery systems in improving wound healing activities of the CUR and its analogs.

TL;DR: This study has utilized guar gum, a natural carbohydrate polymer as a capping layer to contain a model drug, such as 5-flurouracil within the mesoporous channels of MSN and demonstrated near perfect 'zero release' property in absence of enzymes in different simulated conditions of the gastrointestinal tract.

TL;DR: Chitosan-coated and uncoated solid lipid nanoparticles (SLNs) are proposed as a nasal delivery system capable of exploiting both olfactory and trigeminal nerve pathways and it is found that siRNA permeates the monolayer to a greater extent when released from any of the studied formulations than from bare siRNA, and primarily from chitOSan- coated SLNs.

TL;DR: The ability of ATP to participate in single electron transfer reaction, through complexation with Fe3O4 NPs, results in the generation of hydroxyl radicals which are responsible for enhanced peroxidase activity at physiological pH.

TL;DR: This review addresses functionalization strategies for the non-covalent and covalent attachment of monoclonal antibodies and their fragments to liposomal surfaces and explores the main targeting possibilities with these ligands for the treatment of a variety of pathologies.

TL;DR: It is confirmed that CD-DOX complexes increased cancer therapy efficiency through the localization of a much higher quantity of drugs in the nuclei of tumor cells and induced a higher rate of apoptosis in ACC-2 cells, compared to DOX alone.

TL;DR: Chitosan has been used to cross-link poly(acrylic acid) to give three pH-sensitive hydrogels designed to control the release of the drugs amoxicillin and meloxicam that appear to provide an ideal basis for controlled drug delivery systems.

TL;DR: Bioactivity assays showed that the ALG/CS-GA3 nanoparticles were most effective in increasing leaf area and the levels of chlorophylls and carotenoids, and the systems developed showed good potential, providing greater stability and efficiency of this plant hormone in agricultural applications.

TL;DR: The promising therapeutic potential of wound dressings functionalized with AMPs is revealed and the establishment of functionalization methods for wound Dressings over recent years has increased the need for such research.

TL;DR: Feather keratins displayed wound-healing and biodegradation properties similar to those of human hair keratin and were also highly compatible with those of the tissue and devoid of immunogenicity and systematic toxicity, suggesting that feather keratin hydrogel could be used for biomedical applications, particularly effective wound healing.

TL;DR: It is demonstrated that the dual delivery system resulted in synergistic effects and lead to an effective cancer cell apoptosis, which may be promising for cancer therapeutic application.

TL;DR: A pH-triggered oral drug delivery system by capping of mesoporous silica SBA-15 with pH-responsive polymer poly (acrylic acid) (PAA) via a facile graft-onto strategy has promising applications for treatment of colon cancer and other colon diseases.

TL;DR: In this article, the pH sensitive CMC-Ca was found to be fundamentally pH sensitive in solution, if the pH deviated from the pH (7-9) that was used in the synthesis of the nanoparticles.

TL;DR: Structuring emulsions with mixed protein-particle layers with CNCs at the WPI-stabilized oil-water interface could be an effective strategy to tune and control interfacial barrier properties during gastric passage of emulsion.

TL;DR: It is found that the model anticancer drug doxorubicin (DOX) can be efficiently encapsulated in the MSNs in the absence of glutathione (GSH), and a burst release ofDOX is observed when the system is exposed to GSH, indicating good capping efficiency of Tf and redox-responsive release of DOX.

TL;DR: The photodegradation activity of GT/ZPNC was explored for the removal of methylene blue (MB) and fast green (FG) dyes from aqueous solution and the antimicrobial efficiency of GT-Zr(IV) phosphate nanocomposite was investigated against E. coli.

TL;DR: The results demonstrated the scaffold modified with AgNPs could support cell proliferation, and enhanced higher alkaline phosphatase activity compared with pure PEEK scaffold, and this dual functional 3D material holds great potential application in clinical bone tissue repair.

TL;DR: In vitro study on hMSC adhesion, viability, spreading and osteogenic differentiation showed that the PHBV-SiHA scaffolds had the largest adhesion and differentiation abilities compared with other scaffolds.

TL;DR: It was shown that the presence of a positively charged surface allows a better absorption of curcumin in the small intestine phase, which increases the overallCurcumin bioavailability.

TL;DR: It is satisfactorily concluded that co-loaded NLC formulation can be qualified as a splendid parenteral drug delivery system foundation for cancer theragnostic.

TL;DR: In this article, the disinfection process of g-C 3 N 4 -AgBr composites under visible light irradiation was investigated and showed that photo-generated holes, surface bounded OH, and indirect generation of intracellular active species played important roles in disinfection.

TL;DR: In vitro sustained drug release results were corroborated by the extended residence and slow clearance of rifampicin from the lungs, and the minimum lung distribution of drug in treated rats which confirms the negligible toxicity rendered by nanoparticle dry powder formulation.

TL;DR: By tuning the NaCl concentration in the parent chitosan and TPP solutions, low-polydispersity particles with z-average diameters ranging between roughly 100 and 900nm can be prepared, and the dilution method delivers the most uniform/gradual size increase - i.e., it provides the most precise control.

TL;DR: The results suggest that the photothermal effect of the carbon nanotubes can disrupt the structure of the hydrogel with a gel-sol transition, triggering the release of the drug from the sustained drug delivery system by NIR irradiation while responding on demand.

TL;DR: The developed formulations, and in particular SLN (MM)-LN, showed in vitro antiproliferative effects on hepatocarcinoma and lung adenocarc inoma cell lines in a dose-dependent response, and higher inhibitory effects were found in comparison with free LN.

TL;DR: The permeable nanoparticle-gel system may be a potential carrier for the topical delivery of lipophilic anti-psoriatic drugs and inhibit the expression of inflammatory cytokines to a greater extent.