Showing papers in "Current Opinion in Biotechnology in 2022"

TL;DR: In this paper, various techniques have been proposed to intensify and accelerate the phytoremediation of heavy metals in the soil by changing the conditions in the rhizosphere area to favor heavy metals extraction and the transport in the roots and their translocation towards the aerial parts of the plant.

TL;DR: In this paper , various techniques have been proposed to intensify and accelerate the phytoremediation of heavy metals in the soil by changing the conditions in the rhizosphere area to favor heavy metals extraction and the transport in the roots and their translocation towards the aerial parts of the plant.

TL;DR: In this paper, the authors provide a brief overview of the most important aspects to cover when designing mRNA-LNPs from what is currently known and how to optimize them, and their perspective on which of these aspects is most crucial and what are the next steps required to advance the field.

TL;DR: In this article , the authors provide a brief overview of the most important aspects to cover when designing mRNA-LNPs from what is currently known and how to optimize them, and give their perspective on which of these aspects is most crucial and what are the next steps required to advance the field.

TL;DR: In this paper, the identity of the main factors driving plant microbiota structure, diversity, and function in bulk soil, in the rhizosphere, and in the plant organs was identified.

TL;DR: The identification of plant traits that respond to the microbiota form the basis for rational engineering of the plant microbiota to improve sustainable agriculture is discussed in this paper , where beneficial microorganisms have long been used as inoculants for crops.

TL;DR: The potential applications of marine collagen in the regeneration of skin, bone and cartilage were also highlighted in this paper , where the authors reviewed advances in the design and fabrication of marine gelatin-based constructs for medical applications.

TL;DR: Single-cell metabolomics with mass spectrometry enables a large variety of metabolites to be simultaneously detected from individual cells, without any preselection or labelling, to map phenotypes on the single cell level as mentioned in this paper .

TL;DR: In this paper, the authors focus on the efficacy of the electron donor, enzyme stabilization, and how the desired reverse FDH reactivity can be enhanced to achieve robust and efficient FDH catalyzed CO2 conversion for sustainable large-scale implementation.

TL;DR: In this paper , the authors focus on the efficacy of the electron donor, enzyme stabilization, and how the desired reverse FDH reactivity can be enhanced to achieve robust and efficient FDH catalyzed CO2 conversion for sustainable large-scale implementation.

TL;DR: In this article , a broadening of the microalgae species available as single-cell protein, novel food approval is required, in combination with novel biomass pre-treatment steps, will guarantee high quality microalgal protein.

TL;DR: In this article, the authors highlight the challenges and discuss opportunities for use of biological systems to upgrade previously inaccessible waste streams, such as those derived from lignin, biomass pyrolysis, or industrial waste.

TL;DR: In this paper , the authors highlight the challenges and discuss opportunities for use of biological systems to upgrade previously inaccessible waste streams, such as those derived from lignin, biomass pyrolysis, or industrial waste.

TL;DR: In this paper , the authors highlight the recent advances in applying machine learning to protein engineering and discuss supervised learning methods that infer the sequence-function mapping from experimental data and new sequence representation strategies for data-efficient modeling.

TL;DR: In this article, the authors discuss the strategies that have been explored and how each one of them contributes to regulate vascularization in the context of cutaneous wound healing from two different perspectives - biomaterial-based and a cell-based approaches.

TL;DR: In this paper , the authors give an introduction to SCP production by heterotrophic microbial species, phototrophs, methanotrophics and autotrophic hydrogen oxidizers and highlight some challenges and the latest developments in the growing SCP industry.

TL;DR: In this article , the authors discuss recent advances in carbonic anhydrase stabilization by protein engineering and enzyme immobilization, and shed light on state-of-the-art of in vitro and in vivo CA-mediated CO2 conversion for improved production of value-added chemicals using CO2 as a feedstock.

TL;DR: In this paper , the authors discuss the strategies that have been explored and how each one of them contributes to regulate vascularization in the context of cutaneous wound healing from two different perspectives - biomaterial-based and a cell-based approaches.

TL;DR: In this article, the authors summarize non-enzymatic and enzymatic electrochemical approaches for cofactor regeneration, then discuss recent developments to solve major issues such as Rh-catalyst mediated enzyme mutual inactivation, electron-transfer rates, catalyst sustainability, product selectivity and simplifying product purification.

TL;DR: In this article, the authors summarize the current progress in engineering cyanobacteria and discuss the achieved and potential utilization of these advances for the production of the bulk chemical butanol, specifically isobutanol and 1-butanol.

TL;DR: In this paper , the authors focus on recent progress in a subsection of this vast field-synthetic genetics-concerned with encoded synthesis, reverse transcription, and evolution of XNAs.

TL;DR: In this article , the authors summarize the current progress in engineering cyanobacteria and discuss the achieved and potential utilization of these advances for the production of the bulk chemical butanol, specifically isobutanol and 1-butanol.

TL;DR: In this article , the authors summarize non-enzymatic and enzymatic electrochemical approaches for cofactor regeneration, then discuss recent developments to solve major issues such as Rh-catalyst mediated enzyme mutual inactivation, electron-transfer rates, catalyst sustainability, product selectivity and simplifying product purification.

TL;DR: In this article , the micro-environment effects of spatial organization on substrate channeling in natural cascades are reviewed and examples that exploit the microenvironment to improve single enzyme and cascade catalysis are discussed.

TL;DR: In this article, the effects of spatial organization on the microenvironment experienced by assembled enzymes are discussed and examples that exploit the micro-environment to improve single enzyme and cascade catalysis.

TL;DR: In this paper , the performance and technology readiness of electrochemical reduction of CO2 to various components and the respective biotechnological conversions are evaluated in relation to each other and existing gaps for the realization of hybrid microbial electrosynthesis processes are evaluated.

TL;DR: In this paper, the authors argue that the following areas will be central to the development of cyanobacterial cell factories: engineered and well-characterized host strains, model-guided pathway design, and advanced synthetic biology tools.

TL;DR: A review of the most recent findings regarding the infant gut microbiota with a particular focus on the molecular mechanisms by which bifidobacteria impact on host health and well-being is presented in this paper.

TL;DR: In this article , the authors look back on research in these areas, surveying the polyphenols as a case study for health-conferring metabolites, and conclude that the tools that will allow us to breed more nutritious crops are all at hand.

TL;DR: In this article , the authors argue that the following areas will be central to the development of cyanobacterial cell factories: engineered and well-characterized host strains, model-guided pathway design, and advanced synthetic biology tools.