Journal•ISSN: 0959-440X
Current Opinion in Structural Biology
Elsevier BV
About: Current Opinion in Structural Biology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Protein structure. It has an ISSN identifier of 0959-440X. Over the lifetime, 3620 publications have been published receiving 303655 citations.
Topics: Medicine, Protein structure, Protein folding, Structural biology, RNA
Papers published on a yearly basis
Papers
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TL;DR: New structural information has increased the understanding of the structural determinants of LRR proteins and the ability to model such proteins with unknown structures, and has shed new light on how these proteins participate in protein-protein interactions.
1,604 citations
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TL;DR: The diversity of oligo- and polysaccharides provides an abundance of biological roles for these carbohydrates, and the enzymes hydrolysing these compounds, the glycoside hydrolases, mediate a wealth of biological functions.
1,565 citations
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TL;DR: There are now numerous examples of proteins that are unstructured or only partially structured under physiological conditions and yet are nevertheless functional.
1,280 citations
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TL;DR: Structures have recently been reported for many new zinc finger domains with novel topologies, providing important insights into structure/function relationships and into mechanisms of DNA binding and to a better understanding of their broader functions in transcriptional regulation.
1,271 citations
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TL;DR: This work states that proteins have a rugged funnel-like landscape biased toward the native structure as a result of evolution, and connecting theory and simulations of minimalist models with experiments has completely revolutionized the understanding of the underlying mechanisms that control protein folding.
1,242 citations