Journal•ISSN: 1879-6257
Current Opinion in Virology
Elsevier BV
About: Current Opinion in Virology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Virus & Biology. It has an ISSN identifier of 1879-6257. Over the lifetime, 1182 publications have been published receiving 49593 citations.
Topics: Virus, Biology, Viral replication, Immune system, Innate immune system
Papers
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TL;DR: Some of the most potent antiviral effectors reinforce the system by further inducing IFN or ISGs, suggesting that some viruses may have evolved to co-opt IFN effectors for a survival advantage.
1,068 citations
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TL;DR: The potential of metagenomics for characterization of the normal viral population in a healthy community and identification of viruses that could pose a threat to humans through zoonosis is discussed and a new model of the Koch's postulates named the ‘Metagenomic Koch's Postulates’ is proposed.
518 citations
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TL;DR: An overview of the available data from experimental and observational studies on the transmission routes of respiratory viruses between humans is presented, knowledge gaps are identified, and how the available knowledge is currently implemented in isolation guidelines in health care settings is discussed.
436 citations
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TL;DR: The current state of bacteriophage genomics shows that the genetic diversity of the population is very high, that phages have been actively evolving for billions of years with active engagement of horizontal genetic exchange, and that their genomes are consequently pervasively mosaic in their architectures.
381 citations
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TL;DR: Gene transcription signatures unique to SARS-CoV disease states have been identified, but host factors that regulate exacerbated disease phenotypes still remain largely undetermined.
370 citations