Journal•ISSN: 1534-5807
Developmental Cell
Elsevier BV
About: Developmental Cell is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Biology & Medicine. It has an ISSN identifier of 1534-5807. Over the lifetime, 5386 publications have been published receiving 566849 citations. The journal is also known as: Cell.
Topics: Biology, Medicine, Cellular differentiation, Stem cell, Cell biology
Papers published on a yearly basis
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TL;DR: Some key aspects of Wnt/beta-catenin signaling in human diseases including congenital malformations, cancer, and osteoporosis are highlighted, and potential therapeutic implications are discussed.
4,926 citations
TL;DR: It is demonstrated that cell shape regulates commitment of human mesenchymal stem cells to adipocyte or osteoblast fate and mechanical cues experienced in developmental and adult contexts, embodied by cell shape, cytoskeletal tension, and RhoA signaling, are integral to the commitment of stem cell fate.
3,995 citations
TL;DR: This review summarizes the current knowledge about the molecular machinery of autophagy and the role of the autophagic machinery in eukaryotic development and identifies a set of evolutionarily conserved genes that are essential forAutophagy.
3,721 citations
TL;DR: This review summarizes and compares major signaling pathways that regulate the epithelial-mesenchymal transitions during both development and tumor metastasis and examines their role in carcinoma invasion and metastasis.
2,849 citations
TL;DR: RANKL selectively induces NFATc1 expression via TRAF6 and c-Fos signaling pathways, and may represent a master switch for regulating terminal differentiation of osteoclasts, functioning downstream of RANKL.
2,235 citations