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Showing papers in "Diabetes Research and Clinical Practice in 2019"


Journal ArticleDOI
TL;DR: Just under half a billion people are living with diabetes worldwide and the number is projected to increase by 25% in 2030 and 51% in 2045, with the prevalence higher in urban than rural areas, and in high-income than low-income countries.

4,865 citations


Journal ArticleDOI
TL;DR: Worldwide estimates of numbers of children and adolescents with type 1 diabetes continue to increase, but prevalence estimates have decreased in the sub-Saharan Africa because allowance has been made for increased mortality in those with diabetes.

274 citations


Journal ArticleDOI
TL;DR: Difficulty in deriving a meaningful global prevalence rate for DR and DME is illustrated due to the lack of uniformity in defining the study populations, methodological differences, retinal image capture and grading criteria; international consensus is required using a minimal data set for future studies.

191 citations



Journal ArticleDOI
TL;DR: DPP-4i & SGLT-2i are neutral as far as all aspects of CV outcomes are concerned except for hHF which is significantly reduced by the latter.

74 citations


Journal ArticleDOI
TL;DR: FLASH is an effective programme to improve glycaemic control and lower diabetes-related distress in users of FSGM.

70 citations


Journal ArticleDOI
TL;DR: An overview of therapeutic approaches with an anti-AGE or RAGE-antagonizing effect, their outcomes in clinical studies and their role in the management of diabetes and its complications are given.

70 citations


Journal ArticleDOI
TL;DR: In patients with pre-diabetes and hypovitaminosis D, high dose vitamin D improves insulin sensitivity and decreases risk of progression toward diabetes.

69 citations


Journal ArticleDOI
TL;DR: The potential connection between hyperglycemia-associated AGEs formation and the recent evidence of pro-tumoral effects of MGO stress is highlighted and the marked interest in anti-glycation compounds is discussed in view of their strategic use to treat diabetic complications but also to protect against augmented cancer risk in patients with diabetes.

62 citations


Journal ArticleDOI
TL;DR: Attention to infectious oral diseases and referral to dental care professionals for treatment can be an important novel tool for medical care professionals in preventing and managing diabetes mellitus and may contribute to improved health, wellbeing, and quality of life in people with diabetes.

60 citations


Journal ArticleDOI
TL;DR: The smartphone-based IR-camera shows excellent validity for diabetic foot assessment, and diagnostic accuracy showed 94% and 93% sensitivity, and 86% and 91% specificity.


Journal ArticleDOI
TL;DR: Results suggest that RIF ameliorates the genetic expression of antioxidant and anti-inflammatory, and metabolic regulatory genes and implies a protective impact against oxidative stress and its adverse metabolic-related derangements in non-diabetic obese patients.

Journal ArticleDOI
TL;DR: The presence of depression in a person with diabetes should trigger the consideration of evidence-based therapies for cardiovascular disease prevention irrespective of the baseline risk of cardiovascular disease or duration of diabetes.

Journal ArticleDOI
TL;DR: Results indicate that a range of well-being interventions appear to have promise in improving health outcomes in this population of patients with diabetes, but the literature does not yet provide definitive data about which specific interventions are most effective.

Journal ArticleDOI
TL;DR: This prospective study is the first to describe the characteristics and care of participants with T2DM during Ramadan in MENA, and can be utilized in the development of evidence-based care to ensure the safety of participants who fast.

Journal ArticleDOI
TL;DR: RDF lowers visceral adiposity, body weight and variably affects adipokines without adversely affecting markers of glucose homeostasis in individuals with overweight or obesity.

Journal ArticleDOI
TL;DR: Lifestyle-focused text messaging is a low cost initiative aimed at motivating patients with T2DM to adhere to a healthy lifestyle, with a significant improvement in HbA1c in the meta-analysis.

Journal ArticleDOI
TL;DR: Weight loss was maintained but despite this HbA1c increased to above baseline levels in both groups, and there were no significant differences between groups in body composition, fasting glucose levels, lipid levels, or total medication effect score at 24 months.

Journal ArticleDOI
TL;DR: A systematic review of clinical trials investigating the health benefits of physical activity in pediatric patients with type 1 diabetes was performed in this paper, where only randomized controlled trials written in English before 1998 and that answered to the PICOS criteria were included.

Journal ArticleDOI
TL;DR: GDM can be a risk factor for PPD, and PPD examination in pregnant women with GDM seems to be necessary, according to meta-analysis results.

Journal ArticleDOI
TL;DR: High Visceral Adiposity Index was associated with an increased risk of T2DM diagnosis in both sexes, however, it could only predict the development of T1DM in women.

Journal ArticleDOI
TL;DR: Using the Perinatal Data System database, PGDM and GDM, especially PGDM, was associated with higher prevalence of macrosomia, cyanotic heart disease and any birth defect in singleton term pregnancy in Upstate New York.

Journal ArticleDOI
TL;DR: Benefits of diabetes education are mainly observed in terms of patient self-care and metabolic control of diabetes.


Journal ArticleDOI
TL;DR: This is the first bibliometric study on diabetes in Ramadan, a good starting point to evaluate gaps in research activity in the field and should help identify future research directions and foster more collaboration.

Journal ArticleDOI
TL;DR: Low serum Metrnl level was significantly correlated with reduced risk of T2DM as revealed by multivariate logistic regression analysis after control of potential risk factors for diabetes.

Journal ArticleDOI
TL;DR: Waist circumference and waist-to-height ratio were more strongly associated with diabetes than BMI among Chinese adults, and the odds ratios of NDM with waist circumference, WHtR, and BMI per standard deviation (SD) increase were higher than in the total population.

Journal ArticleDOI
TL;DR: Pooled risk estimates reveal that polypharmacy is associated with increased all-cause mortality, macrovacular complications and hospitalization using categorical definitions, and assert the need for interventions that optimize the balance of benefits and harms in medicines prescribing.

Journal ArticleDOI
TL;DR: Empag liflozin was more effective in reducing HbA1c and improving other cardiometabolic parameters than dapagliflozin and SGLT2 inhibitors can be effectively used as a fourth OAD in T2D patients who are treated with three other OADs.