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Showing papers in "Domestic Animal Endocrinology in 2000"


Journal ArticleDOI
TL;DR: The role of plasma IGF-I during compensatory growth is not clear and must be explained in connection with changes of its binding proteins, which seem to have a permissive effect on growth.

425 citations


Journal ArticleDOI
TL;DR: The results of this study support the idea that leptin might play a role in regulating numerous physiological functions.

174 citations


Journal ArticleDOI
TL;DR: A possible clinical relevance of nitric oxide production associated with a rise of intramammary and systemic TNF-alpha during acute mastitis by E. coli infection and endotoxin in lactating dairy cows is indicated, but could not be inhibited by antibiotic treatment.

173 citations


Journal ArticleDOI
TL;DR: The investigations suggest that blood growth hormone (GH) is important for mammary development, and that the negative effect of high feeding level on Mammary development may be due to reduced blood GH, however, GH does not bind to mammary tissue.

159 citations



Journal ArticleDOI
TL;DR: The observed absence of suppression of gonadotropins and leptin in aged and young mares may reflect the maintenance of sufficient levels of metabolizable fuels, rather than a failure of leptin to signal nutritional status to the reproductive axis of the mare.

125 citations


Journal ArticleDOI
TL;DR: It is concluded that selenium acts on granulosa cells by modulating their proliferation and E2 synthesis; moreover, its effect could be mediated, at least in part, through an inhibition of nitric oxide.

107 citations


Journal ArticleDOI
TL;DR: This report provides the first evidence for the presence of leptin in sow milk; its function in the physiology of suckling pigs remains to be determined.

99 citations


Journal ArticleDOI
TL;DR: In this paper, the effects of different concentrations of dietary fat and i.v. administration of a cholecystokinin receptor antagonist (MK-329) on feed intake and plasma concentrations of hormones and metabolites in dairy cattle were investigated.

57 citations


Journal ArticleDOI
TL;DR: Estrogen receptors (ER) were determined by both the biochemical dextran-coated charcoal (DCC-ER) and the immunohistochemical Avidin biotin-peroxidase complex (IHC-ER methods in proliferative mammary lesions collected from 37 cats: 20 malignant tumors without metastasis at first presentation, sevenmalignant tumors with lung and/or lymph node metastases and 10 benign tumors and dysplasias.

57 citations


Journal ArticleDOI
TL;DR: In this paper, the effect of feed restriction and re-alimentation on the onset of puberty and IGF status in peripubertal male calves and to compare the radioimmunoassay (RIA) and western ligand blotting (WLB) methods for bovine IGFBP-2.

Journal ArticleDOI
TL;DR: It is demonstrated that German shepherd dwarfs have a combined deficiency of GH, TSH, and prolactin together with impaired release of gonadotropins, whereas ACTH secretion is preserved.

Journal ArticleDOI
TL;DR: Physiological differences in leptin, a potent regulator of food intake and energy metabolism, may be important factors in the genetic variation in sensitivity to environmental stress.

Journal ArticleDOI
P Cordano1, H.M. Hammon1, C. Morel1, Andreas Zurbriggen1, J.W. Blum1 
TL;DR: The major hepatic components of the GH-IGF axis were present in neonatal calves, but the IGF-I expression and therefore also plasma IGF- I levels were relatively low.

Journal ArticleDOI
TL;DR: Evidence is provided to suggest that insulin may be an important component of hypothalamic mechanisms regulating secretion of LH and expression of leptin receptors in undernourished ruminants.

Journal ArticleDOI
TL;DR: The RIA developed in the present study is specific to the chicken and thus may be considered as powerful tool for investigating the physiological significance of leptin in chickens.

Journal ArticleDOI
TL;DR: The number of successful artificial inseminations was increased by an average of 6.0% NRR when ejaculates from rbGH-treated bulls were used, and motility of spermatozoa after freezing and thawing was increased compared with pretreatment rates.

Journal ArticleDOI
TL;DR: The results of this study demonstrate pulsatile secretion of TSH in dogs during hypothyroidism and only small fluctuations in plasma TSH concentrations during euthyroidism, and suggest that the low TSH values occasionally found in dogs with spontaneous primary hypothyrogenism may in some cases in part be the result of ultradian fluctuations.

Journal ArticleDOI
TL;DR: The results suggest that the prolactin axis of the mare is sensitive to an inhibitory melatonin signal during a restricted period of time and that at other times is refractory to this signal.

Journal ArticleDOI
TL;DR: Divergent selection experiments have shown that upward or downward selection on growth is effective, sometimes with asymmetrical responses, but patterns of changes in underlying physiological traits appear to differ among experiments.

Journal ArticleDOI
TL;DR: It is suggested that regular hormone changes start from 10 days after birth and that the periods from birth to 4 weeks of age and the last 5 weeks before the first ovulation in heifers are important to the development of reproductive functions before puberty.

Journal ArticleDOI
TL;DR: The present study evaluated somatotrophic gene expression in liver, muscle and adipose tissue 4 d after weaning, a time point corresponding to greatly reduced serum concentrations of insulin-like growth factor (IGF)-1 and IGF-2 in pigs.

Journal ArticleDOI
TL;DR: It is concluded that a 7-day infusion of IGF-I directly into the stroma of the ovary altered follicular growth and follicular fluid estradiol concentrations.

Journal ArticleDOI
TL;DR: The increase in lamb birth weight associated with mid-pregnancy shearing may have been associated with an increase in the non-insulin dependent uptake of glucose by the placental-fetal unit.

Journal ArticleDOI
TL;DR: It is indicated that mild LPS challenge in cattle inhibits hepatic generation of T3 and decreases plasma concentrations of thyroid hormones and the impact of LPS on 5'D activity in liver can be altered by Arg supplementation.

Journal ArticleDOI
TL;DR: Results indicate that plasma IGF-I concentrations increase during estrus in goats, and GH was secreted in an episodic manner in the estrous and luteal phases in goats.

Journal ArticleDOI
TL;DR: This study showed that peripubertal boars express a typical circadian melatonin rhythm under both artificial light regimens and in standard pig stable environment, and natural photoperiod and indoor lighting seem to interact in shaping the melatonin profile in standard stable environment.

Journal ArticleDOI
TL;DR: IFN-tau may regulate the PGF(2a) synthetic pathway by reducing activity of PKC or PKC mediated events and to determine if arachidonic acid (AA) is limiting in endometrial tissue of pregnant cows.

Journal ArticleDOI
TL;DR: Identifying biochemical criteria for disease processes provides needed guidance for the further development of intervention strategies to limit the impact of disease on growth.

Journal ArticleDOI
TL;DR: It is strongly believed that the plasma IGF-1 and IGFBPs response to KP102 treatment is modulated by the nutritional status of growing Holstein steers and the increased plasma IGF -1 concentration with KP 102 treatment may be regulated by plasma 38-43 kDa IGFBP-3 and 24 k da IGF BP-4 in Holstein Steers.