Journal•ISSN: 1167-1122
European Journal of Dermatology
John Libbey Eurotext
About: European Journal of Dermatology is an academic journal published by John Libbey Eurotext. The journal publishes majorly in the area(s): Medicine & Psoriasis. It has an ISSN identifier of 1167-1122. Over the lifetime, 5531 publications have been published receiving 67287 citations. The journal is also known as: EJD & European journal of dermatology (Montrouge).
Topics: Medicine, Psoriasis, Dermatology, Population, Atopic dermatitis
Papers published on a yearly basis
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Journal Article•
TL;DR: The main data concerning the anatomy, histology and immunohistochemistry of normal human skin are reviewed.
Abstract: The skin is the largest organ of the body, accounting for about 15% of the total body weight in adult humans. It exerts multiple vital protective functions against environmental aggressions, rendered possible thanks to an elaborate structure, associating various tissues of ectodermal and mesodermal origin, arranged in three layers, including (from top to bottom) the epidermis (and its appendages), the dermis and the hypodermis. This article reviews the main data concerning the anatomy, histology and immunohistochemistry of normal human skin.
513 citations
Journal Article•
418 citations
TL;DR: This guideline represents an evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guideline, and a brief overview of epidemiological aspects and clinical management of patients with BCC.
Abstract: Disclaimer. This guideline for the management of basal cell carcinoma (BCC) is based on that prepared by the British Association of Dermatologists and has been prepared by the BCC subcommittee of the Guidelines Committee of the European Dermatology Forum. It represents an evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guideline, and a brief overview of epidemiological aspects and clinical management of patients with BCC. Many different and well-accepted treatments are used in the management of BCC. [1] This guideline aims to aid selection of the most appropriate treatment for individual patients.
345 citations
Journal Article•
TL;DR: The frequent deregulation of EGFR expression and activation in benign and malignant hyperproliferative skin diseases motivates the investigation of EG FR-dependent intracellular pathways which contribute to the varied EGFR-dependent phenotypes.
Abstract: Epidermal keratinocytes express both the epidermal growth factor receptor (EGFR) and several of its ligands, establishing the constitutive elements of an autocrine loop in this cell type. Activation of the EGFR provides signals essential to several aspects of normal keratinocyte biology including cell cycle progression, differentiation, cell movement and cellular survival. It may be argued that enhanced keratinocyte survival via EGFR activation is the most important function as it limits the manifestation of other phenotypes. The frequent deregulation of EGFR expression and activation in benign and malignant hyperproliferative skin diseases motivates the investigation of EGFR-dependent intracellular pathways which contribute to the varied EGFR-dependent phenotypes.
302 citations
TL;DR: Extranodal natural killer (NK)/T-cell lymphoma (ENKL) is a unique disease entity that is strongly associated with Epstein–Barr virus (EBV) infection.
Abstract: Extranodal natural killer (NK)/T-cell lymphoma (ENKL) is a unique disease entity that is strongly associated with Epstein–Barr virus (EBV) infection. This disease is more common in Asia and Central and South America but is rare in North America and Europe. Pathologically, ENKL involves polymorphous infiltration of variable-size lymphocytes with accompanying inflammation and necrosis. The malignant cells express cytoplasmic CD3 and CD56. EBV is detected by EBV-encoded small RNA (EBER) in situ hybridization.
296 citations