Showing papers in "European Journal of Organic Chemistry in 2005"
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TL;DR: In this paper, the gelation of aqueous solutions by low molecular weight (LMW) compounds has become an area of increasing interest, owing to developments in the field of LMW organogelators.
527 citations
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TL;DR: In this paper, a review deals with some recent advances relating to [2 + 2+2+2] cycloaddition reactions involving the syntheses both of polycycles and of heterocycles.
420 citations
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TL;DR: In this article, the Bamford-Stevens reaction was used to generate diazo compounds in the presence of phase-transfer-catalysts (PTCs) and showed the usefulness of this chemistry in a number of different transformations, such as Wittig olefination and the sulfur ylide mediated epoxidation.
314 citations
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TL;DR: The Nazarov cyclization is a 4π-electron conrotatory cyclization of a pentadienyl cation that leads to a five-membered ring, typically a cyclopentenone as mentioned in this paper.
301 citations
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TL;DR: In this article, the authors show that weak bases may play the role of promoters in the decarboxylation of symmetric and unsymmetric ketones. But they do not discuss the effect of weak bases.
282 citations
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TL;DR: Many methods have been developed for the enantio-and diastereoselective synthesis of α,α-disubstituted α-amino acids, many of which are focused on the total synthesis of natural products and related bioactive compounds as mentioned in this paper.
268 citations
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TL;DR: The asymmetric Suzuki-Miyaura coupling has recently emerged as an attractive alternative to standard methods for the control of biaryl axial chirality as discussed by the authors, and some applications in target-oriented synthesis are discussed in this microreview.
250 citations
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TL;DR: In this article, the Paal-Knorr cyclocondensation of 1,4-diketones with amines and other nitrogen derivatives is used for the preparation of pyrroles and related heterocycles.
234 citations
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TL;DR: In this article, it was shown that the activation energy of the nucleophilic substitution at sp2 nitrogen is almost the same as that of the Beckmann rearrangement at sp 2 carbons, while such an SN2-type substitution reaction was found to proceed readily at the sp 2 nitrogen of oximes.
230 citations
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TL;DR: Palladium/Et3B induces allyl alcohols to undergo electrophilic allylation of soft carbon nucleophiles (pKa 5−14), alkyl aldehydes at the α-position, and amines, indoles, and tryptophan at the 3-position as mentioned in this paper.
224 citations
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TL;DR: In this paper, a microreview of recent syntheses of polyhydroxylated piperidines is presented, focusing on recent synthesises of azasugars and their analogs.
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TL;DR: The asymmetric aza-Michael reaction has emerged as a very powerful tool for the synthesis of chiral β-amino carbonyl compounds, as will be discussed in this paper.
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TL;DR: There is a demand for new methods of protecting organic dyes from aggregation effects and photochemical degradation as discussed by the authors, and molecular encapsulation is an attractive supramolecular strategy because it is inherently flexible and does not necessarily require time-consuming synthetic processes.
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TL;DR: In this paper, a cross-dehydrogenative coupling (CDC) reaction was proposed to construct β-amino diesters and β-dicyano amines by a combination of two different sp3 C-H bonds followed by C-C bond formation.
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TL;DR: The use of fluorine has become well established in the analysis of protein structure and function, e.g. in tools such as 19F NMR spectroscopy as discussed by the authors, but the influences of amino acid fluorination on side-chain interactions in proteins are still controversially discussed.
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TL;DR: The importance of conformational pre-organization in successful macrocyclization reactions has been recognized ever since Eschenmoser's synthesis of vitamin B12 and Woodwards synthesis of erythromycin this article.
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TL;DR: In this paper, a formal [3 + 3] cycloaddition strategy for constructing complex heterocycles is reviewed, which involves condensation of α,β-unsaturated iminium salts with 1,3-dicarbonyl equivalents.
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TL;DR: In this paper, a conformationally rigid P-chiral bis(trialkylphospholane) ligand 2 (DuanPhos) has been prepared in both enantiomeric forms through a concise syn-thesis.
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TL;DR: Transition metal catalyzed decarboxylation of β-keto acids and esters provides a convenient route for the regiospecific generation of enolates under neutral conditions as mentioned in this paper.
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TL;DR: In this paper, a bifunctional organocatalysts bearing both a thiourea moiety and an imidazole group on a chiral scaffold were synthesized and applied to the Strecker synthesis and nitro-Michael reaction.
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TL;DR: In this article, the volatiles released by two strains of the myxobacterium Chondromyces crocatus and seven strains of marine Alphaproteobacteria from the North Sea were collected using the CLSA or SPME headspace methods and analysed by GC-MS.
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TL;DR: In this paper, the chiral N-acylhydrazones were used as versatile imino acceptors for the addition of radicals and nucleophiles, and they achieved high stereoselectivity for addition reactions in the presence of Lewis acids.
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TL;DR: The development of milder and more sophisticated halogenating reagents that offer significantly greater chemoselectivity and stereocontrol than diatomic halides has been critical to the realization of asymmetric α-halogenation as discussed by the authors.
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TL;DR: In this article, a facile and high-yielding synthesis of multivalent 1,4-disubstituted 1,2,3-triazole-linked glycodendrimers is described.
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TL;DR: In this article, the effect of extended acetylenic conjugation on the absorption and fluorescence properties of 1,3,6,8-tetraethynylpyrene derivatives was studied.
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TL;DR: The preparation of substituted dihydrofurans remains a current challenge in organic synthesis and a microreview details the various routes employed for their synthesis in the literature to the end of 2004.
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TL;DR: The Zn-proline complex has been shown to catalyze the aldol reaction of acetone and a wide range of arenecarbaldehydes in aqueous media, accepting even deactivated arene carbaldehyders such as methoxybenzaldehyde in good yields.
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TL;DR: In this article, the classical Biginelli reaction is considerably extended by use of cycloalkanones instead of 1,3-dicarbonyl compounds, and a possible mechanism to account for the reaction is proposed.
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TL;DR: In this article, the relative configuration of phomoxanthone A (1a) was elucidated by X-ray single-crystal analysis, which revealed that the axial chirality along the biaryl axis dominates the CD spectra of the dimeric xanthone 1a, and can thus be determined by CD calculation as (aS).
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TL;DR: In this article, the authors present a new enantioselective synthesis of benzylisoquinoline alkaloids. But their work is restricted to the case of (+)-(S)-laudanosine and (−)- (S)-xylopinine.