Showing papers in "European Journal of Organic Chemistry in 2008"

TL;DR: A review of the use of No-Carrier-added (NCA) [18F]fluoride ion in the preparation of 18F-labeled radiotracers for PET can be found in this paper.

TL;DR: In this paper, the Suzuki-Miyaura cross-couplings of organoboronic acids or organotrifluoroborates with aryl and alkenyl halides or triflates have become classic methods for generating carbon-carbon bonds.

TL;DR: Microreview as mentioned in this paper focuses on recent developments made in the field of micro reaction technology, highlighting the advantages associated with its use through the synthesis of a diverse array of molecules and highlights the potential of a compound, however, depends not only on structural complexity, but also on the ability to prepare the compound via a scalable synthetic pathway.

TL;DR: Indazoles are of considerable interest due to the broad variety of their biological activities as mentioned in this paper, and a comprehensive overview of pharmacologically interesting indazoles can be found in this paper.

TL;DR: In this article, a microreview provides an overview of the recently developed aryl iodide-catalyzed oxidations, in which hypervalent organoiodanes(III and V) generated in situ serve as the actual oxidants.

TL;DR: In this paper, a review traces the evolution of the methodologies for creating stereogenic centers through asymmetric copper-catalyzed allylic alkylation with the use of different organometallic reagents and their subsequent applications.

TL;DR: The electrospray ionization mass spectrometry (ESI-MS) has been used extensively in the last two decades to study reaction mechanisms of organic molecules as mentioned in this paper.

TL;DR: In this paper, a short overview on how to introduce the anisotropic environment necessary to measure residual dipolar couplings, the corresponding measurement methods and the applications for the determination of the relative configurations and the assignment of diastereotopic moieties is presented.

TL;DR: The use of chiral ionic liquid (CIL) as solvents, catalysts, or ligands in asymmetric synthesis is discussed in this article, where the authors focus entirely on the applications of CILs; publications dealing with design and synthesis of cILs only are not mentioned.

TL;DR: In this paper, the asymmetric bioreduction of C=C-bonds bearing an electron-withdrawing group, such as an aldehyde, ketone, imide, nitro, carboxylic acid, or ester moiety by a novel enoate reductase from Zymomonas mobilis and Old Yellow Enzymes OYE 1−3 from yeasts furnished the corresponding saturated products in up to 99%

TL;DR: In this paper, a microreview focused on the synthesis of 3-phenyl-3-(trifluoromethyl)diazirine, one of the most promising photophores, and its application to biomolecules.

TL;DR: The reactions of phosphinylidene-containing compounds with unactivated unsaturated hydrocarbons are reviewed and free-radical and metal-catalyzed additions of R(1)R(2)P(O)H to alkenes, alkynes, and related compounds, deliver functionalized organophosphorus compounds RP(O), including H-phosphinates, phosphinates, tertiary phosphines, and phosphonates.

TL;DR: In this article, a Johnson-type methyl transfer reagent was designed for electrophilic trifluoromethylation of carbon nucleophiles, which was used for the first time for dicyanoalkylidenes.

TL;DR: Amphiphilic cyclodextrins represent a new generation of these oligosaccharides, which are well known previously as host molecules in water as discussed by the authors, but showing additional supramolecular properties.

TL;DR: In this paper, the C-S cross coupling of thiols with aryl halides in the presence of tetrabutylammonium bromide in water was investigated.

TL;DR: In this article, 3,5-disubstituted pyrazoles are synthesized from acyl chlorides, terminal alkynes, and hydrazines by a consecutive one-pot three-component Sonogashira coupling/Michael addition/cyclocondensation sequence in good to excellent yields.

TL;DR: In this article, a selective over-view of the recent developments of microwave-assisted, transition-metal-catalysed C-C and C-N bond-forming reactions is presented.

TL;DR: In this article, the authors used a catalytic amount of KI in combination with TBHP as the external oxidant to avoid the use of expensive and/or air-sensitive reagents.

TL;DR: In this article, a silica-immobilized NHC-CuI complex was developed and used as a highly efficient catalyst in the three-component coupling reactions of aldehydes, alkynes and amines.

TL;DR: In this article, high-dastereoselective nucleophilic additions to cyclic nitrones derived from L-malic acid and D-arabinose have been used for the construction of enantiomerically pure polyhydroxylated pyrrolidines.

TL;DR: In this article, the synthesis of oseltamivir phosphate, an important orally active anti-influenza drug, has been reviewed for the first time in the literature.

TL;DR: In this article, a three-component reaction for propargylamines from aldehydes, amines, and terminal alkynes has been proposed using a heterogeneous catalyst and in the absence of solvent.

TL;DR: In this paper, the amination of secondary alcohols to give tertiary amines in the presence of different in situ generated ruthenium catalysts has been investigated in detail.

TL;DR: In this article, a modification of the Friedlander reaction, 2-aminobenzyl alcohol is oxidatively cyclized with a variety of ketones to yield substituted quinolines.

TL;DR: The alpha-oxysulfonylation of ketones catalysed by enantioenriched iodoarenes using mCPBA as stoichiometric oxidant is reported to give useful synthetic intermediates in good yield and modest enantioselectivity, believed to be the first report of an enantiOSElective organocatalytic reaction involving hypervalent iodine reagents.

TL;DR: In this paper, the beneficial effect of microwave irradiation instead of classical thermal conditions in olefin metathesis reactions is illustrated through a series of literature examples of ring-closing and cross-metathesis reaction.

TL;DR: In this article, a detailed comparison of the group-IV metal catalysts Ti(NMe 2 ) 4, Ind 2 TiMe 2, Ind 2 ZrMe 2 and Ind 2 HfMe 2 in the intramolecular hydroamination of amino alkenes is presented.

TL;DR: Nano copper oxide has been found to be a highly efficient and reusable catalyst for the C-O cross-coupling of phenols with aryl halides under ligand-free conditions as mentioned in this paper.

TL;DR: In this paper, the use of combinations of amino acids, amines, K 2CO3 or Cs2CO3 and CuSO4/Cu for catalysing green cascade reactions was investigated.

TL;DR: In this paper, the authors summarize developments in the recently discovered area of palladium-catalyzed asymmetric Michael additions of organometallic reagents to activated electron-deficient olefins in its practical and theoretical aspects.