Showing papers in "Experimental Parasitology in 2015"

TL;DR: Overall, low doses of AuN may help to boost the control of Anopheles and Aedes larval populations in copepod-based control programs.

TL;DR: This study provides novel information about susceptibility ofAvian hosts to a wide array of malaria parasite lineages, outlining directions for future experimental research on various aspects of biology and epidemiology of avian malaria.

TL;DR: It is demonstrated that IL-17A and IL- 17 receptor signaling are essential for intestinal defense against the important lumen-dwelling intestinal parasite Giardia.

TL;DR: The effect of diluting samples of Plasmodium-containing blood samples to allow accurate relative measures of gametocyte densities and their impact on mosquito infectivity and TRI efficacy is described.

TL;DR: The objective of this study was to compare the expression of digestive enzymes, nutrient transporters and an antimicrobial peptide in broilers challenged with either E. acervulina, E. maxima or E. tenella to explain the weight loss in avian coccidiosis.

TL;DR: The morphological, biological, and molecular characteristics of Cryptosporidium piscine genotype 1 from the guppy are described, and the species name Cryptospora huwi n.

TL;DR: The results showed that the rTsNd protein was able to interact with host IECs, had the Nudix hydrolasing activity and the enzymatic activity appeared to be essential indispensable for the T. spiralis larval invasion, development and survival in host.

TL;DR: Sensitive and specific quantitative ddPCR assays for the detection of B. microti and B. duncani in blood could be used as sensitive approaches to monitor the progression of parasitemia in rodent models of infection as well as serve as suitable molecular tests in blood screening.

TL;DR: It is demonstrated that TsNd DNA delivered by attenuated live S. typhimurium elicited a local IgA response and a mixed Th1/Th2 immune response, and produced a partial protection against T. spiralis infection in mice.

TL;DR: Analysis of plasma miRNAs obtained from malaria patients and normal subjects suggests that plasma miR-451 and miR -16 are relevant biomarkers for malaria infection.

TL;DR: TS can be considered as a promising alternative to the standard therapy for treating acute murine toxoplasmosis and enhanced its efficacy and allowed its use in a lower dose.

TL;DR: It is speculated that the fish in that group acquired high protective immunity following poly-infection by C. irritans, experiencing limited harm for pompano.

TL;DR: It was demonstrated that activation of astrocytes and microglia/macrophages is a significant event in toxoplasma encephalitis (TE), and the results clearly indicated that increased levels of NO might contribute to neuropathology related with TE.

TL;DR: The present study indicated that Pere David's deer are naturally infected with E. bieneusi, predominantly with zoonotic genotypes, and may pose a risk for human transmission.

TL;DR: Clinical symptoms were not associated with the prevalence of Cryptosporidium and Giardia infections in cats, and the domestic cats in the present study are likely to be of low zoonotic risk to pet owners in Perth.

TL;DR: Compared with each other, HTS has excellent potential for revealing the "true" composition of species/types in a Cryptosporidium infection, but that HTS workflows need to be carefully developed to ensure sensitivity, accuracy and contamination are controlled.

TL;DR: The laminated layer is the unique mucin-based extracellular matrix that protects Echinococcus larvae, and thus to an important extent, shapes host-parasite relationships in the larval echinococcoses.

TL;DR: The sensitivity of a rodent model was evaluated and, conclusively, C57Bl/6 mice were most susceptible to subcutaneous inoculation of small numbers of sodium hypochlorite-resistant oncospheres, even more than to oral inoculations of mature eggs.

TL;DR: It can be concluded that the essential oil obtained from the aerial parts of B. dracunculifolia and its major component nerolidol have high activity on R.

TL;DR: A series of novel hybrid 4-aminoquinoline 1,3,5-triazine derivatives was synthesized in a five-steps reaction and evaluated for their in vitro antimalarial activity against chloroquine-sensitive and chloroquin-resistant strains of Plasmodium falciparum.

TL;DR: The transmission electronic microscopy showed that TrEO was able to modify the promastigote ultrastructures suggesting autophagy as chromatin condensation, blebbing, membranous profiles and nuclear fragmentation, and TrROY showed loss toxicity to erythrocytes cells.

TL;DR: A new species, Isospora serinuse n.

TL;DR: The results indicate that the sensitivity and specificity of each test is highly dependent on the input samples; while Kinyoun's and DFAT proved to be reliable screening tools for cattle samples, DFAT and PCR analysis were more sensitive for screening sheep and horse samples.

TL;DR: It is demonstrated that juglone significantly inhibits the growth of Acanthamoeba castellanii at 3-5 μM concentrations, and results indicate that ROS played a significant role in the jugl one-induced cell death of AcAnthamoebA.

TL;DR: It is shown that Giardia cysts have limited ability to repair UV-induced damage and this may have implications for drinking- and waste-water treatment when setting criteria for the use of UV disinfection to ensure safe water.

TL;DR: Evaluating the cellulose SD in vivo, improving the effectiveness of its NaDC equivalent and suggesting these solid dispersions as alternative drug delivery systems to improve the limited chemotherapy of Chagas disease are suggested.

TL;DR: This study showed that (-)α-bisabolol has promising antileishmanial properties, as it can act against the promastigotes forms and is able to penetrate the cell, and is also active against the amastigote forms.

TL;DR: The mechanism of action established for these leishmanicidal natural products provides a new outlook in the search for drugs against Leishmania.

TL;DR: It is concluded that maternal infection with Toxoplasma gondii Wh3 isolate of genotype Chinese 1 during pregnancy may contribute to trophoblast apoptosis by oxidative stress-induced mitochondrial dysfunction and activation of the downstream signaling pathway.

TL;DR: Ethyl acetate fraction (EAF) alone was found to exhibit leishmanicidal effect validated through cytotoxicity assay and estimated its IC₅₀ to be 52.4 µg/ml on the promastigote stage, and propidium iodide staining of dead cells substantiated the aforementioned activity.