Showing papers in "FEBS Letters in 2007"

TL;DR: This review summarizes the present knowledge of the individual members of human Hsp70 family and elaborate on the functional differences between the cytosolic/nuclear representatives.

TL;DR: Many of the new insights are derived from recently constructed mouse models where the genes encoding the chaperones are genetically altered, providing invaluable tools for examining the physiological involvement of the ER chaperone in vivo.

TL;DR: In a comparison between higher plants and unicellular algae, hypotheses are generated for evolutionary changes in metal transporter complements associated with the transition to multicellularity.

TL;DR: In higher plants, two types of nitrate transporters, NRT1 and NRT2, have been identified and in barley, HvPTR1, expressed in the plasma membrane of scutellar epithelial cells, is involved in mobilizing peptides to the developing embryo.

TL;DR: The aim of this review is to highlight the recent progress in understanding of Na+ transport in plants and discuss the ability to deal with the toxic effects of Na+.

TL;DR: Some of the components regulating iron deficiency responses also have been elucidated, demonstrating that iron dependent gene regulation occurs at both the transcriptional and post‐transcriptional levels.

TL;DR: An overview of recent studies on the mechanisms of autophagosome formation is given and unresolved questions about the mechanisms underlying autophagy remain unanswered.

TL;DR: This review will highlight results on the regulation, localization and physiological roles of these H+‐ pumps, namely the plasma membrane H-ATPase, the vacuolar H‐ATPases and the vacUolar H-PPase.

TL;DR: It is shown that co‐expression of P2X7R with pannexin1 in oocytes leads to the complex response seen in many mammalian cells, including cell death with prolonged ATP application, while the cation channel activity is resistant to carbenoxolone treatment, and this gap junction and hemichannel blocking drug suppressed the currents induced by ATP.

TL;DR: The crystal structure of Sav1866 in complex with adenosine‐5′‐(β,γ‐imido)triphosphate (AMP‐PNP) at 3.4 Å resolution confirms that the ATP‐bound state of multidrug ABC transporters is coupled to an outward‐facing conformation of the transmembrane domains.

TL;DR: A review throws light on the current status of blood CNA as a diagnostic marker and its potential as a powerful tool in the future.

TL;DR: This paper reviews the current knowledge of sucrose transporter physiology and molecular biology and describes how sucrose transport depends on the activity of plasma membrane‐localized, energy dependent, H+‐symporting carrier proteins.

TL;DR: In this article, the authors introduce aspects of the physiology and biology of oxygen partial pressure and the molecular mechanisms implicated in oxygen sensing, and outline the regulation and function of the key operator in cellular signalling of hypoxia.

TL;DR: The aryl hydrocarbon (dioxin) receptor (AhR) has been studied for several decades largely because of its critical role in xenobiotic‐induced toxicity and carcinogenesis and studies supporting the implication of the AhR in those endogenous cellular processes are summarized.

TL;DR: The possession of a wide range of receptors for the Hsp and Grp family permits binding to a diverse range of cells and the performance of complex multicellular functions particularly in immune cells and neurones.

TL;DR: The review summarizes the current understanding of the molecular mechanisms of organic nitrogen transport processes, with a focus on amino acid, ureide and peptide transporters.

TL;DR: This review will discuss the contribution of members of each family to potassium acquisition, redistribution and homeostasis in plant potassium transporters.

TL;DR: The present review focuses on the most recent findings concerning the molecular and cellular properties of plant aquaporins, and the mechanisms of transport selectivity and gating have recently been described.

TL;DR: It is shown that in olive leaves salinity induces nitrosative stress, and vascular tissues could play an important role in the redistribution of NO‐derived molecules during nitrosatives stress.

TL;DR: Progress made to date in developing pharmacological modulators of the heat shock response is described, including both agents which affect the entire heatshock response and those that specifically target the HSP70 and HSP90 chaperone families.

TL;DR: Membrane rafts are regions of increased lipid acyl chain order that differ in their lipid and protein composition from the surrounding membrane and their potential involvement in different forms of membrane traffic is reviewed.

TL;DR: This review summarizes the current knowledge about Hsp27 and αB‐crystallin and the implications, either positive or deleterious, of these proteins in pathologies such as neurodegenerative diseases, myopathies, asthma, cataracts and cancers.

TL;DR: The different families of K+‐selective channels that have been identified in plants, the so‐called Shaker, TPK and Kir‐like channels, and what is known so far on their regulations and physiological functions in the plant are described.

TL;DR: To improve efficiency for blast search, an implementation that can identify homologs of miRNAs and their targets, with high sensitivity and specificity is developed, allowed to be run on Windows Operation System platform.

TL;DR: Recent genetic and biochemical studies that are beginning to yield exciting insights into the fusion mechanisms of Saccharomyces cerevisiae mating pairs, Caenorhabditis elegans epithelial cells and gametes, Drosophila melanogaster and mammalian myoblasts, and mammalian macrophages are discussed.

TL;DR: TNTs have been shown to facilitate the intercellular transfer of organelles as well as, on a limited scale, of membrane components and cytoplasmic molecules.

TL;DR: Al3+ resistance genes of several species have been isolated and found to encode membrane proteins that facilitate organic anion efflux from roots that belong to the Al3+‐activated malate transporter (ALMT) and multi‐drug and toxin extrusion (MATE) families.

TL;DR: Human attachment seems to employ a push–pull mechanism that overcomes social distance by deactivating networks used for critical social assessment and negative emotions, while it bonds individuals through the involvement of the reward circuitry, explaining the power of love to motivate and exhilarate.

TL;DR: An update on the currently available information on these Arabidopsis monosaccharide transporters, on their sub‐cellular localization and physiological function will be given.

TL;DR: It is shown that one of these compounds, T0901317, is also a high‐affinity ligand for the xenobiotic receptor pregnane X receptor (PXR), suggesting that many of the biological activities heretofore associated with LXR activation may be mediated by PXR, not LXR.