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Showing papers in "Fertility and Sterility in 1979"


Journal ArticleDOI
TL;DR: The antiperoxidant factor present in human seminal plasma effectively counteracts the toxic effect of exogenous peroxidized fatty acids upon human spermatozoa, but is unable to restore motility lost by lipid peroxide action.

749 citations


Journal ArticleDOI
TL;DR: Hospital and clinic charts for 100 patients with diagnosed Müllerian anomalies were reviewed and a new classification, based on degree of failure of normal development, was used in separating the anomalies into groups with similar clinical manifestations, treatment, and prognosis for fetal salvage.

565 citations


Journal ArticleDOI
TL;DR: The data suggest that human spermatozoa fuse with the vitelline membrane of zona-free hamster eggs and decondense with varying efficiencies, and may have potential value as a diagnostic tool in evaluating human semenatozoal fertilizing capacity.

286 citations


Journal ArticleDOI
TL;DR: The utility of the system as a once-a-month injectable contraceptive is established in the baboon model and the effects of continuous progesterone therapy on reproductive function in both rats and baboons are dose-dependent.

266 citations


Journal ArticleDOI
TL;DR: The chlamydial serum immunoglobulin G antibodies of 128 infertile women were determined by a single-antigen (L2) immunofluorescence test and the operative findings were typical of previous salpingo-oophoritis.

226 citations


Journal ArticleDOI
TL;DR: In this paper, a mathematical model of fertility from demographers is used to predict the cumulative probability of conception over time, given a certain monthly probability for conception or fecundability.

221 citations


Journal ArticleDOI
TL;DR: The present study suggests that salt-stored eggs can be used as substitutes for fresh living eggs in the preliminary assessment of fertilizing capacity of spermatozoa when collection of a large number of fresh unfertilized eggs, particularly in humans, is not practical.

218 citations


Journal ArticleDOI
TL;DR: Although no change was noted in semen quality standards, the authors concur with earlier suggestions that the minimal standards recommended by the American Fertility Society be modified.

214 citations



Journal ArticleDOI
TL;DR: A simple, objective method is described for obtaining a well-defined and diversified set of human sperm movement characteristics that are suitable for comprehensive statistical comparisons of sperm suspensions.

150 citations


Journal ArticleDOI
TL;DR: The chronic effects of long-distance running upon the menstrual cycle were studied in a healthy, ovulatory 30-year-old woman to find that the luteal phase was shorter in cycles of greater mileage.

Journal ArticleDOI
TL;DR: In this article, 100 couples with documented recurrent reproductive failure were evaluated in the reproductive endocrine unit of the Medical College of Georgia from 1968 through 1977, all couples underwent cytogenetic studies, radiologic evaluation of the Mullerian system and timed endometrial biopsy.

Journal ArticleDOI
TL;DR: In this paper, the effects of human seminal plasma on the fertilizing capacity of human spermatozoa were investigated using zona-free hamster eggs and salt-stored human eggs.

Journal ArticleDOI
TL;DR: Data from studies examining the effects of vasectomy in a large number of nonhuman primates vasectomized for periods ranging up to 14 years are summarized, and these findings and speculations are used as a framework with which to review the subject of autoimmunity and vasectomy.

Journal ArticleDOI
TL;DR: In three patients when no medical contraindication existed, discontinuation of the drug resulted in a dramatic improvement in the semen quality, and all three reported pregnancies within the ensuing 3 months.

Journal ArticleDOI
TL;DR: Full-complement component lytic activity was measured in human midcycle cervical mucus, using a sensitive 51Cr release hemolytic assay, and the relevance of this level of complement to complement-dependent sperm-immobilizing antibody activity was studied.

Journal ArticleDOI
TL;DR: There was a suggestion that most endometriosis is least responsive to progestogens, and Histologic dating revealed a delay in the most aberrant endometrial tissue in adenomyosis, as compared with dating of corresponding normal endometrium.

Journal ArticleDOI
TL;DR: Clomiphene is a safe, relatively inexpensive and convenient method of ovulation induction and deserves its prominent place in the treatment of the infertile woman.

Journal ArticleDOI
TL;DR: Danazol, a heterocyclic steroid related chemically to 17 alpha-ethinyltestosterone (ethisterone), is currently approved by the FDA for treatment of endometriosis only but other clinical applications of the drug may be found for both endocrine and nonendocrine disorders.

Journal ArticleDOI
TL;DR: Population homogeneity with anovulation as the major cause of infertility appears to be the most plausible explanation for the high pregnancy rate.

Journal ArticleDOI
TL;DR: The data suggest that if medical suppressive therapy is to be used in conjunction with conservative surgery to enhance fertility, it should be used preoperatively rather than postoperatively, and that surgery is efficacious.

Journal ArticleDOI
TL;DR: It is concluded that persistent azoospermia after an accurate microscopic vasovasostomy results from the secondary epididymal obstruction induced by rupture of the epididcyal duct related to the pressure increase after vasectomy.

Journal ArticleDOI
TL;DR: Nine patients vasectomized elsewhere and specifically referred to us for chronic and persistent postvasectomy orchialgia, seven had no sperm granuloma at the vasectomy site, and pain in these cases was localized in the epididymis and was relieved by vasovasotomy.

Journal ArticleDOI
TL;DR: Danazol was found to possess androgenic and glucocorticoid activity in rat bioassays as discussed by the authors, but showed no significant estrogenic activity in the uterus.

Journal ArticleDOI
TL;DR: The use of bromocriptine with human menopausal gonadotropic and human chorionic gonadotropin was beneficial in treating hypog onadotropic hypogonadism with hyperprolactinemia.

Journal ArticleDOI
TL;DR: In this paper, a combination of ethinylestradiol (EE) and dl-norgestrel as a postcoital contraceptive agent was studied in 12 healthy female volunteers.


Journal ArticleDOI
TL;DR: In utero diethylstilbestrol (DES) exposure has been associated with apparently unique abnormalities of the upper genital tract as mentioned in this paper, where the endometrial cavity area, upper uterine segment, and endocervical canal measurements were significantly smaller in the DES-exposed group.

Journal ArticleDOI
TL;DR: The ratio of male to female conceptions in this small study parallels the ratio of Y to X sperm in the final specimen used for artificial homologous insemination.

Journal ArticleDOI
TL;DR: Using absorbable suture as a stent, end-to-end anastomosis of previously ligated or cauterized fallopian tubes was performed in 15 cases, and the importance of repeated hydrotubations to maintain tubal patency is emphasized.