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Showing papers in "Fertility and Sterility in 1980"


Journal ArticleDOI
TL;DR: There are no longer any easy answers to infertility and when male infertility is the problem couples are turning in record numbers to donor insemination and other alternatives force the couple to face adjustments and issues that may be as difficult as the original problem of infertility.

356 citations



Journal ArticleDOI
TL;DR: Elevated levels of serum human chorionic gonadotropin and progressively increasing levels of total urinary estrogens and pregnanediol confirmed the presence of an early pregnancy.

294 citations


Journal ArticleDOI
TL;DR: It is suggested that successful treatment of endometriosis may require both the eradication of existing endometrial plaques and the prevention of reseeding over the peritoneum resulting from retrograde menstruation.

278 citations


Journal ArticleDOI
TL;DR: In this article, the Kretz Combison 100 sector scanner was used to scan the ovaries of healthy volunteers with regular ovarian function, women taking oral contraceptives, and infertile patients being treated with clomiphene.

237 citations



Journal ArticleDOI
TL;DR: Sixty cases of ectopic pregnancy were treated by laparoscopy without laparotomy, finding only 3 were failures, and the operated fallopian tube was checked in 18 cases and in 13 of these was found to be patent.

185 citations


Journal ArticleDOI
TL;DR: In this paper, a total of 77 treatment cycles of human menopausal gonadotropin (hMG)-human chorionic gonadotropic (hCG) were administered to 41 infertile patients with polycystic ovarian disease who failed to conceive on clomiphene.

183 citations



Journal ArticleDOI
TL;DR: The role of microsurgery in reversal of sterilization has been reassessed and 118 cases reviewed and an inverse relationship was noted between the total length of the reconstructed oviducts and the occurrence of pregnancy.

144 citations


Journal ArticleDOI
TL;DR: The surgically modified oviduct, capture of ova by the fimbriae, adhesion formation, and the pathophysiology of damaged tubes have been dealt with through microsurgery, finding the technique is superior to those results obtained with implantation.

Journal ArticleDOI
TL;DR: In this article, an experimental model was developed using New Zealand White rabbits to study the effect of endometriosis on fertility, and the authors found that the increased prostaglandin (PG) levels in peritoneal fluid may alter follicular rupture, ovum transport, corpus luteum function, or implantation.

Journal ArticleDOI
TL;DR: Although hyperprolactinemia, recurrent miscarriages, extremes of reproductive life, and clomiphene citrate administration have been associated with an increased incidence of the defect, in this series a predisposing cause could not be detected in approximately one-half of the patients.

Journal ArticleDOI
TL;DR: Preovulatory eggs in cumulus were inseminated in vitro with washed spermatozoa which had been preincubated for 1.5 hours and each egg contained a nucleus at a stage of development similar to that of the early pronuclei.

Journal ArticleDOI
TL;DR: Kinetic experiments indicated that eggs were maximally penetrated after 5 hours of exposure to capacitated sperm and that the cessation in sperm incorporation seen at this time resulted from egg-related changes that occurred during aging in vitro.

Journal ArticleDOI
Alan O Trounson1, John Leeton1, Carl Wood1, Janice Webb1, Gabor T. Kovacs1 
TL;DR: A simple regimen involving the use of clomiphene and human chorionic gonadotropin which enabled laparoscopy to coincide with available surgical lists resulted in the recovery of mature oocytes from 15 of the 18 patients treated, and apparently normal embryos developed from five of six oocytes recovered from patients who had blocked fallopian tubes.

Journal ArticleDOI
TL;DR: A new experimental and theoretical procedure is described for characterizing the penetration of spermatozoa into cervical mucus in vitro, and clinical application of the method to human semen and cervical mucUS is described, and sample results are presented.

Journal ArticleDOI
TL;DR: Ibuprofen appeared to inhibit the formation of significant adhesions as compared with adhesion formation in untreated control animals, and the results seemed as effective as in the dexamethasone-treated animals.


Journal ArticleDOI
TL;DR: Given its inoffensive nature, the usefulness of echography in determining the physical event of ovulation is demonstrated and possible applications in the surveillance of ovulating methods and in artificial insemination are discussed.

Journal ArticleDOI
TL;DR: This paper reviews and evaluates various methods for the prediction and detection of ovulation, with emphasis on the role this plays in management of infertility and in natural family planning.

Journal ArticleDOI
TL;DR: The hypothesis postulated by some investigators that the luteinized unruptured follicle (LUF) syndrome may be the cause of infertility in women with endometriosis does not appear to be accurate, however, endocrine factors probably play a role in the origin of LUF.


Journal ArticleDOI
TL;DR: In this paper, a large-scale evaluation of primary and secondary infertility patients was performed at a large referral center in the US and the results showed that LPD was discovered in 32 of 396 patients (8.1%) and pregnancy was not complicated by other abnormalities.

Journal ArticleDOI
TL;DR: Clinical surveillance and immunologic, hematologic, and biochemical tests indicated excellent local and systemic tolerance to the antigen, and no significant adverse effects on menstrual function, endocrine status, or health were found.

Journal ArticleDOI
TL;DR: The importance of diagnostic and operative laparoscopy and possible laparotomy in all infertile women who had an otherwise complete and normal evaluation for infertility is demonstrated by the high rate of significant unsuspected findings in these women and a term pregnancy rate of greater than 50% following treatment.

Journal ArticleDOI
TL;DR: Follicular dimensions based on the volume of aspirated fluid correlated well with the ultrasound measurements, which suggests that ultrasound is a useful technique for examining preovulatory follicular development.


Journal ArticleDOI
TL;DR: The data show that apparent abnormalities in adrenal steroid biosynthesis are a frequent occurrence in patients with hyperandrogenism.

Journal ArticleDOI
TL;DR: Determination of blood serum levels of luteinizing hormone (LH) are used to detect the day of the midcycle surge and hence the time of ovulation, solely from knowledge of the average length and variability of a woman's cycles, without the need for determinations of LH.