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Showing papers in "Fertility and Sterility in 1991"


Journal ArticleDOI
TL;DR: In a 3-year prospective study of 643 consecutive laparoscopies for infertility, pelvic pain, or infertility and pain, the pelvic area, the depth of infiltration, and the volume of endometriotic lesions were evaluated.

781 citations


Journal ArticleDOI
TL;DR: In this paper, the results with immature human follicular oocytes harvested from unstimulated ovaries, matured in vitro, fertilized, and transferred to an agonadal recipient were described.

544 citations


Journal ArticleDOI
TL;DR: Follicle-stimulating hormone level was a better predictor than age for all outcome variables examined and remained a significant predictor after accounting for age, etiology of infertility, and semen quality.

465 citations


Journal ArticleDOI
TL;DR: In this paper, the role of natural killer (NK) cells in the decreased cellular immunity of women with endometriosis was investigated, and the cytotoxicity, directed against the endometrium, was mediated by NK cells.

370 citations


Journal ArticleDOI
TL;DR: Greenhall and Vessey as discussed by the authors compared the conclusions of their own report on trends in infertility in the United States with those of E. Greenhall and M. Vessey concerning Great Britain and concluded that physicians providing infertility services do not have more patients due to an epidemic of infertility because there is no epidemic.

320 citations


Journal ArticleDOI
TL;DR: In this article, the authors evaluated gender differences in psychosocial responses of 449 consecutive first-admission couples in a fertility clinic and found that infertile women showed higher distress than their partners on a global measure of psychiatric symptoms and subscales of anxiety, depression, hostility, and cognitive disturbances, as well as on measures of stress and self-esteem.

306 citations


Journal ArticleDOI
TL;DR: The usefulness of the septum resection in patients with septate uterus and no previous reproductive failure is questioned.

278 citations


Journal ArticleDOI
TL;DR: In this paper, a bolus of gonadotropin-releasing hormone agonist (GnRH-a) is able to trigger an adequate midcycle LH/FSH surge, resulting in oocyte maturation and pregnancy.

273 citations


Journal ArticleDOI
TL;DR: The results indicate a very high efficiency for in vitro fecundity provided optimal conditions are attained and the concepts leading to success in the ovum donation model should set the course for continued research toward improving results in other forms of assisted reproduction.

266 citations


Journal ArticleDOI
TL;DR: In this paper, the authors evaluated the adhesion formation after laparoscopy as compared with laparotomy in a randomized trial and concluded that laparoscopic treatment of ectopic pregnancy results in less impairment of the pelvic status compared with conventional conservative surgery.

264 citations


Journal ArticleDOI
TL;DR: There is a definite identifiable pattern of subendometrial myometrial contractility that varies with the phases of the normal menstrual cycle and recurs in a similar fashion from cycle to cycle.

Journal ArticleDOI
TL;DR: When the relatively low direct and indirect costs of controlled ovarian hyperstimulation and IUI are considered, acknowledging the lack of prospective, controlled studies, this procedure appears to be at least as cost-effective as GIFT and IVF.

Journal ArticleDOI
TL;DR: In this article, sperm samples from 179 male infertility patients were analyzed for type and number of white blood cells (WBC) by a combination of immunologic techniques and showed that elevated levels of WBC in semen are associated with poor semen quality.

Journal ArticleDOI
TL;DR: Laroscopic excision of endometriosis results in a low rate of minimal persistent/recurrent disease, which suggests a rather static nature of the disease.

Journal ArticleDOI
TL;DR: In this article, it was shown that polycystic ovarian syndrome (PCOS) typically arises from masculinized regulation of the androgen-forming enzyme (cytochrome P450c17 α ) within ovarian thecal cells.

Journal ArticleDOI
TL;DR: The relationship of the circulating level of progesterone (P) on the day of human chorionic gonadotropin (hCG) injection to occurrence of clinical pregnancy was examined in 133 leuprolide acetate human menopausal (hMG) in vitro fertilization cycles in women having at least three embryos transferred.

Journal ArticleDOI
TL;DR: It is possible that these cytokines have a role in the regulation of embryonic development, maternal immunological recognition of pregnancy, and maintenance of proper hormonal environment.

Journal ArticleDOI
TL;DR: Routine vasography has shown that ejaculatory duct obstruction is not as rare as previously thought and the diagnosis should not be missed because the condition is simple to correct surgically in certain cases.

Journal ArticleDOI
TL;DR: In this paper, the authors examined endocrine and clinical responses to long-term administration of RU486 in patients with endometriosis and found that daily administration of the drug resulted in acyclic ovarian function and improvement in subjective painful symptoms of endometriumosis.

Journal ArticleDOI
TL;DR: Peritoneal fluid data indicate that retrograde transport of viable endometrial cells during menstruation occurs in most women with patent tubes, and a significant correlation with number of cell colonies was found in women with infertility and no mechanical and male infertility factors.

Journal ArticleDOI
TL;DR: In this paper, the hypothesis that treatment with clomiphene citrate (CC) and intrauterine insemination (IUI) results in increased fecundity when compared with periovulatory intercourse in couples with either unexplained infertility or surgically corrected endometriosis was tested.

Journal ArticleDOI
TL;DR: There are changes in the flow velocity patterns of the uterine and ovarian arteries during the normal ovulatory menstrual cycle, and it can be suspected that they may involve angiogenesis as well as hormonal factors.

Journal ArticleDOI
TL;DR: New criteria for automatic sorting of all HA patterns that are consistent with the classical descriptions are defined and the incidence of HA is significantly associated with multiple fertilization endpoints.

Journal ArticleDOI
TL;DR: In this article, supernatant fluids from embryo culture media were analyzed after 24 hours and 48 hours for the presence of interleukin-1-alpha (IL-1) and the percent of immunosuppression in 108 consecutive IVF cycles between June 1989 and October 1989.

Journal ArticleDOI
TL;DR: This study in isolated hypo gonadotropic hypogonadism patients is consistent with the two-cell two-gonadotropin hypothesis, that both gonadotropins are required to accommodate their synergistic action for appropriate steroidogenesis.

Journal ArticleDOI
TL;DR: It is possible that some classes of antibiotic agents, such as the penicillins or the quinolones, may have minimal effects on male fertility and maintain the clinical efficacy for patients requiring long-term antibiotic suppressive therapy.

Journal ArticleDOI
TL;DR: Among a total of 379,779 women with 383,589 infants born in Sweden (1983 to 1986), 7.8% had a recorded period of infertility of at least 1 year, and Singleton infants showed an increased percentage of low-birth weight infants, short gestational duration, and signs of intrauterine growth retardation.

Journal ArticleDOI
TL;DR: The GnRH-a stimulation test is a sensitive predictor of performance in the flare-up IVF cycle and the E2 pattern was predictive of the duration and number of ampules of gonadotropin required for stimulation.

Journal ArticleDOI
TL;DR: In this paper, the effect of different EGF concentrations on both denuded and cumulus-enclosed mouse oocytes cultured in vitro was studied and the percentage of oocytes undergoing germinal vesicle breakdown (GVBD) and polar body one formation over time as a function of EGF concentration was determined.

Journal ArticleDOI
TL;DR: It is concluded that while day 5 ET may well be important in terms of embryo biopsy for the preimplantation diagnosis of genetic disease, day 2 ET remains preferable for therapeutic IVF.