Showing papers in "Fertility and Sterility in 1995"
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TL;DR: It is demonstrated that, in morphologically and developmentally normal human embryos, cleavage-stage aneuploidy significantly increases with maternal age, and the results suggest that implantation failure in older women largely could be due to aneuPLoidy.
676 citations
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TL;DR: There is ample evidence that WBC can affect sperm function and further studies are needed to define cofactors that increase or decrease the risk of sperm damage by WBC.
382 citations
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TL;DR: Seminal plasma from infertile men has lower antioxidant levels than that of fertile men, particularly of patients whose semen have poor sperm motility, and the presence of reactive oxygen species activity in sperm of infertiles groups also is associated with lower levels of chain-breaking antioxidants in seminal plasma.
345 citations
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TL;DR: In this paper, a randomized, controlled trial of high spermatic vein ligation was carried out to determine whether high ligation is an effective treatment for infertile men with clinical varicocele.
344 citations
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TL;DR: In this paper, integrin cell adhesion molecules as markers were used to assess uterine receptivity in women with unexplained infertility using endometrial biopsies obtained during the window of implantation (days 20 to 24).
343 citations
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TL;DR: Intracytoplasmic sperm injection can be used successfully to treat couples who have failed IVF or who have too few spermatozoa for conventional methods of in vitro insemination, and sperm parameters do not clearly affect the outcome of this technique.
342 citations
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TL;DR: The estimation of live birth among untreated infertile couples is sufficiently accurate to be useful in the clinical management of infertility and in the planning of clinical trials.
320 citations
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TL;DR: The literature consistently demonstrates the value of diminished ovarian reserve screening, and physicians are urged to validate the threshold values with the assay system used in their own laboratory before the application of these tests.
316 citations
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TL;DR: Oral administration of vitamin E significantly improves the in vitro function of human spermatozoa as assessed by the zona binding test in a double-blind randomized placebo cross-over controlled trial.
314 citations
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TL;DR: Although HSG is of limited use for detecting tubal patency because of its low sensitivity, its high specificity makes it a useful test for ruling in tubal obstruction.
308 citations
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TL;DR: In this paper, the authors describe the preparation of fresh or frozen-thawed epididymal and testicular sperm for intracytoplasmic single sperm injection and compare the fertilization, embryo quality, and pregnancy rates obtained after using these spermatozoa to the results when freshly ejaculated sperm was used for microinjection.
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TL;DR: For patients undergoing IVF without GnRH analogue, oocyte numbers and PRs decrease with increasing levels of day 3 E2, and combining day 3 FSH and E2 improved the prognostic ability of either of these hormones used alone.
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TL;DR: In this article, the mtDNA deletions in oocytes were detected in single oocytes, represented by a 0.5-kb band when primers separated by 5kb were used.
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TL;DR: Sperm from infertile men may contain an increased frequency of chromosomal abnormalities, as determined by sperm karyotypes and the disomy frequency determined by fluorescence in situ hybridization analysis.
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TL;DR: It was found that women recalled the stress of the waiting period as greater than their ongoing experience of it as measured by their daily ratings, which indicates that stress is related to IVF outcome.
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TL;DR: Compared with women who had oophorectomy for endometriosis, patients who underwent hysterectomy with ovarian conservation had 6.1 times greater risk of developing recurrent pain and 8.2 times greater chance of reoperation.
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TL;DR: Although preferential recall of family history by women with early menopause could contribute to the association between family history and earlyMenopause observed in this study, a genetic factor is also plausible including partial deletions of the X chromosome compatible with the deficiency of male siblings in cases with family history of early Menopause.
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TL;DR: In this article, the authors evaluated the prognostic value of day 3 E 2 levels, independent of FSH levels, on responses to ovulation induction and subsequent pregnancy rates (PRs) in IVF-ET patients.
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TL;DR: It is hypothesized that IL-8 is an important angiogenic factor that contributes to the pathogenesis of endometriosis by promoting the neovascularization of ectopic endometrial implants.
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TL;DR: To reanalyze data that were used in a linear model to predict that mean sperm counts have been reduced globally by approximately 50% in the last 50 years, several different statistical models were reanalyzed.
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TL;DR: Placental protein 14 produced a potent, fast, and dose-dependent inhibition of binding of human spermatozoa to the human ZP without affecting other prefertilization events (i.e., hyperactivated motility or AR); the detrimental effect on sperm-zona interaction seems to be specific for this endometrial epithelial protein.
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TL;DR: Overall average success rates (deliveries per procedures) exhibited only a small increase compared with previously reported summaries, and there were more programs offering more treatment cycles of ART in 1993.
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TL;DR: It is suggested that even in women exhibiting normal ovarian function a 2.5-fold difference in FSH threshold concentrations for follicle recruitment does occur and the magnitude of decrease in serum FSH concentrations during the follicular phase affects dominant follicle E2 production.
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TL;DR: In this article, the role of genetic and environmental factors in polycystic ovarian syndrome (PCOS) by using the classic twin model was examined, and it was found that fasting insulin level, androstanediol glucuronide and body mass index (BMI) were significantly influenced by genetic factors.
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TL;DR: The available circumstantial evidence suggests that laparoscopic procedures designed to induce ovulation may be of value in the PCOS subject who, despite an exhaustive trial of clomiphene citrate therapy, remains anovulatory and is unable or unwilling to undergo gonadotropin therapy.
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TL;DR: Although acyclicity is seen at all three doses, an effective dose to cause a clinically significant decrease in leiomyomata volume appears to be 25 mg daily.
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TL;DR: In this article, the presence of N -nitro-larginine methyl ester (l-NAME) inhibitor in the male reproductive tract was confirmed by using the nitric oxide synthase-specific inhibitor.
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TL;DR: In this article, the effect of stage and activity of endometriosis and autoantibody positivity on IVF cycle parameters, including pregnancy rates, was analyzed in women with and without endometria.
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TL;DR: Nitric oxide reduces sperm motility, possibly by a mechanism involving inhibition of cellular respiration independent of an elevation of intracellular cGMP, as measured by the tetrazolium-formazan assay.
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TL;DR: Pregnancy outcome in patients with endometriosis was not different than the outcome for patients with mechanical (tubal) infertility, and there were no differences in PRs by stage of endometRIosis.