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Showing papers in "Fertility and Sterility in 1996"


Journal ArticleDOI
TL;DR: The concept that the efficiency of human reproduction is maximum at approximately 30% per cycle is supported, with a very significant number of these pregnancies end in spontaneous abortion.

517 citations


Journal ArticleDOI
TL;DR: Treatment of patients after myomectomy with Seprafilm significantly reduced the incidence, severity, extent, and area of postoperative uterine adhesions and was not associated with an increase in postoperative complications.

433 citations


Journal ArticleDOI
TL;DR: In this paper, the authors reviewed current knowledge on the risk of ectopic pregnancy (EP), with the exception of contraceptive methods, and found that previous EP, previous tubal surgery, documented tubal pathology, and in utero diethylstilbestrol (DES) exposure were associated strongly with the occurrence of EP.

413 citations


Journal ArticleDOI
TL;DR: In this article, a 10-point linear analog scale, a 7-point multidimensional rating scale, and a 3-point verbal scale were used to assess the severity of chronic pelvic pain.

382 citations


Journal ArticleDOI
TL;DR: The data show no decline in sperm counts over a 25-year period in 1,283 men who banked sperm before vasectomy at three distinct geographical sites in the United States.

379 citations


Journal ArticleDOI
TL;DR: In this article, the levels of metabolites surrounding the human oocyte and embryo in vivo were determined by microfluorimetry, which indicated that the early human embryo is exposed to low glucose and high lactate levels in vivo.

342 citations


Journal ArticleDOI
TL;DR: In this paper, a large-scale study identified genetic, endocrine, infectious, anatomical, or autoimmune factors in approximately 60% of couples with habitual abortion, including structural genetic factors, luteal phase deficiency and hypothyroidism.

336 citations


Journal ArticleDOI
TL;DR: The incidence of heterotopic pregnancies increased in recent years because of the escalating use of new reproductive technologies in infertile patients and has stabilized at approximately 1:100 pregnancies with these procedures.

299 citations


Journal ArticleDOI
TL;DR: It is concluded that in this population of healthy young men there has not been any decline in semen quality in the past 21 years.

232 citations


Journal ArticleDOI
TL;DR: In this article, peritoneal macrophages were cultured in the presence or absence of lipopolysaccha-ride (LPS) for 24 hours to evaluate basal (constitutive) and stimulated synthesis of tumor necrosis factor α (TNF α ), interleukin (IL)-8, and IL-10 in women with endometriosis.

231 citations


Journal ArticleDOI
TL;DR: Poor responders do not benefit from high-dose hMG stimulation; their reproduction outcome is poor.

Journal ArticleDOI
TL;DR: In this paper, the spatial distribution of vascular endothelial growth factor protein in human endometrium and to assess temporal fluctuations in VEGF gene expression and variant isoform production by stromal and epithelial cells during the menstrual cycle were determined.

Journal ArticleDOI
TL;DR: RU486 appears to be effective in improving the symptoms and causing regression of endometriosis in the absence of significant side effects.

Journal ArticleDOI
TL;DR: It is concluded that, in patients with endometriosis, implantation rate is low and normal implantation, which may be secondary to endometrial dysfunction or embryotoxic environment, is a factor in endometricriosis-associated subfertility.

Journal ArticleDOI
TL;DR: Ovarian follicular activity, previously considered to be rare, as in the "resistant ovary syndrome," is found in the majority of women with POF using pelvic ultrasonography, and is associated with higher bone mineral density compared with women in whom ovaries could not be identified.

Journal ArticleDOI
TL;DR: The establishment of normal endometrial receptivity appears to be tightly associated with the down-regulation of epithelial PR, and two cycle-dependent integrin markers, alpha 1 beta 1 and alpha 4 beta 1, were not different between groups.

Journal ArticleDOI
TL;DR: It is concluded that the use of ovulation induction agents, in particular hMG, may increase the risk of epithelial ovarian tumors.

Journal ArticleDOI
TL;DR: Vitamin E may improve the fertilization rate of fertile normospermic males with low fertilization rates after 1 month of treatment, possibly by reducing the lipid peroxidation potential, and with no change of the quantitative ultramorphologic analysis of subcellular organelles.

Journal ArticleDOI
TL;DR: Nonobstructive azoospermia caused by maturation arrest may be treated with testicular sperm extraction with ICSI apparently as successfully as Sertoli cell only.

Journal ArticleDOI
TL;DR: 3-D US examination of the endometrial cavity correlated with hysterosalpingography in all patients with Müllerian anomalies and may be used reliably in an office setting to diagnose and classify Müllersian anomalies.

Journal ArticleDOI
TL;DR: In this paper, the ability of antioxidants to reduce the loss of sperm motility caused by reactive oxygen species generated by polymorphonuclear leukocytes (PML) was assessed.

Journal ArticleDOI
TL;DR: Embryo implanting ability and survival decline gradually after 30 years of age, but by more than two thirds after 40 years and in younger women with reduced ovarian capacity.

Journal ArticleDOI
TL;DR: Number of cigarettes smoked per day, years smoked, and log-transformed cotinine levels were associated negatively with semen quality (density, total count, and motility); smoking is associated with lowered semen quality.

Journal ArticleDOI
TL;DR: A body of literature suggests a small but clinically significant detrimental effect of female smoking on both time to conception and spontaneous abortion risk, and the consistent dose-response effect in both the spontaneous conception and abortion literature and a return to normal fecundity among exsmokers suggest a causal association.

Journal ArticleDOI
TL;DR: The prevalence of antiphospholipid antibodies in addition to cardiolipin in women with recurrent pregnancy loss is described and the importance of careful standardization, quality control, and interpretation of positive results is emphasized.

Journal ArticleDOI
TL;DR: In this article, a direct comparison between two patient groups whose oocytes were matured in vitro and a comparison of the embryo development of in vitro-matured oocytes from untreated patients with in vivo matured oocytes of superovulated IVF-ET patients obtained during the same period was conducted.

Journal ArticleDOI
TL;DR: This finding suggests that cellular mechanism of insulin resistance in PCOS is different from other common insulin-resistant states such as non-insulin dependent diabetes mellitus and obesity.

Journal ArticleDOI
TL;DR: Reanalysis of published data from a meta-analysis of 61 studies from 1938 to 1990 that concluded a worldwide decline in semen quality over the last 50 years to determine whether geographic variations in sperm counts might bias conclusions drawn from studies of semen quality.

Journal ArticleDOI
TL;DR: In this paper, the frequency of chromosomal abnormalities in products of conception from women with and without a history of recurrent spontaneous abortion was compared, and no differences in frequency of abnormal karyotype were observed in products-of-conception from women having recurrent spontaneous abortions compared with women without recurrent spontaneous abortions.