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Showing papers in "Fertility and Sterility in 2005"


Journal ArticleDOI
TL;DR: Serum AMH represents the best endocrine marker to assess the age-related decline of reproductive capacity, and shows the best consistency over time.

571 citations


Journal ArticleDOI
TL;DR: In patients with PCOS, the prevalence of IR was 64% according to the HOMA-IR measurement, after adjustment, and patients with IR were more clinically affected.

526 citations


Journal ArticleDOI
TL;DR: The improved SCD protocol (Halosperm kit) results in better chromatin preservation, therefore highly contrasted halo images can be accurately assessed using conventional bright-field microscopy after Wright staining, making it possible to unequivocally discriminate sperm from other cell types.

405 citations


Journal ArticleDOI
TL;DR: Transvaginal ultrasonography is an easy-to-perform and noninvasive method that provides essential predictive information on ovarian responsiveness and the predictive performance of AFC toward poor response is significantly better than that of basal FSH.

336 citations


Journal ArticleDOI
TL;DR: The origin of ROS seems to have an influence on the site of the damage in sperm functions, and the threshold given by the World Health Organization (WHO) should be re-evaluated.

296 citations


Journal ArticleDOI
TL;DR: Chronic alcohol consumption has a detrimental effect on male reproductive hormones and on semen quality.

290 citations


Journal ArticleDOI
TL;DR: At present, the clinician must base their clinical practice on the few high-quality observational studies and intervention trials available rather than on meta-analyses, as there is a scarcity of good clinical trials.

263 citations


Journal ArticleDOI
TL;DR: A convenient simple regimen of administering an aromatase inhibitor as a single dose has been found to have comparable success to a 5-day regimen for ovarian stimulation.

259 citations


Journal ArticleDOI
TL;DR: Blastocyst biopsy and cryostorage and later transfer of biopsied blastocysts is shown to be a practical and probably preferable path to preimplantation genetic testing of embryos compared with cleavage-stage embryo biopsy, being accompanied by a high implantation rate and by a low rate of twinning and miscarriage.

253 citations


Journal ArticleDOI
TL;DR: It is concluded that the three clinical phenotypes of PCOS do not represent forms of the same metabolic disorder and may be the result of varying degrees of metabolic dysfunction; greater degrees of beta-cell function and circulating insulin levels favored the development of hirsutism and frank hyperandrogenemia.

252 citations


Journal ArticleDOI
TL;DR: Infants conceived through IVF have a slightly higher rate of major birth defects, and more birth defects are noted among children born to infertile couples treated with IUI, although this difference is not statistically significant.

Journal ArticleDOI
TL;DR: It is found that clonogenicity does not vary from the proliferative to secretory stage of the menstrual cycle, or between active, cycling and inactive endometrium for both epithelial and stromal cells.

Journal ArticleDOI
TL;DR: Prior function and relationship factors are more important than hormonal determinants of sexual function of women in midlife.

Journal ArticleDOI
TL;DR: PGD reduces the risk of miscarriage in RM patients to baseline levels and has a beneficial effect on pregnancy outcome in RM couples, especially those in which the woman is aged > or =35 years.

Journal ArticleDOI
TL;DR: Adding 2.5 mg of letrozole to a high-dose FSH/hMG antagonist protocol increases intraovarian androstenedione and T concentration and improves IVF cycle outcome in poor responder patients.

Journal ArticleDOI
TL;DR: Advances in surgical instruments and techniques are expanding the role of laparoscopic myomectomy in well-selected individuals, and meticulous repair of the myometrium is essential for women considering pregnancy after laparoscopy to minimize the risk of uterine rupture.

Journal ArticleDOI
TL;DR: Large epidemiologic studies are needed to further study the association between BWS and ART and the culture media could be implicated as a common factor among the children with BWS conceived after ART.

Journal ArticleDOI
TL;DR: The HA sperm selection method for ICSi, which is based on a relationship between sperm receptors for zona pellucida and HA, will likely reduce the potential genetic complications and adverse public health effects of ICSI.

Journal ArticleDOI
TL;DR: This is the first report of hESC derivation in the absence of serum on qualified pathogen-free human feeders and newly derived hESCs were adapted to growth on a human placental laminin substrate in a defined medium.

Journal ArticleDOI
TL;DR: There is a need to first address physical and mental health issues before addressing plans for family building, and clinicians need to be sensitive to the emotional aspects of this disorder when delivering the diagnosis and during subsequent management.

Journal ArticleDOI
TL;DR: This treatment for endometriosis with significant pain relief using anastrazole and 20 microg ethinyl estradiol/0.1 mg levonorgestrel with minimal side effects is a promising new modality that warrants further investigation.


Journal ArticleDOI
TL;DR: The VCUAM classification for the first time makes it possible to reflect even complex malformations in a precise and individual fashion, taking associatedmalformations into account, and makes it easier to provide appropriate clinical care for the affected patients.

Journal ArticleDOI
TL;DR: The administration of LC and LAC is effective in increasing sperm kinetic features in patients affected by idiopathic asthenozoospemia and improves the total oxyradical scavenging capacity of the seminal fluid in the same population.

Journal ArticleDOI
TL;DR: Examination of the demographic and socioeconomic characteristics of patients accessing infertility services in a state with mandated and comprehensive insurance coverage for such services in Massachusetts found the majority of individuals accessing those services being Caucasian, highly educated, and wealthy.

Journal ArticleDOI
TL;DR: The transfer of fresh embryos and female-factor infertility were independently associated with preterm birth and LBW for both singletons and twins after ART.

Journal ArticleDOI
TL;DR: Fetal serum levels are comparable with maternal values and metformin passes the placenta, and the levels of these substances are similar to that of a normal pregnancy.

Journal ArticleDOI
TL;DR: It is demonstrated that high numbers of uNK in preimplantation endometrium of women with recurrent miscarriage can be reduced with administration of prednisolone.

Journal ArticleDOI
TL;DR: Evidence is provided that integrity of sperm DNA influences a couple's fertility and helps predict the chances of pregnancy and its successful outcome.

Journal ArticleDOI
TL;DR: Among subjects with DD, those with deep infiltrating endometriosis of the uterosacral ligament have the most severe impairment of sexual function; the presence of bilateral lesions does not influence the severity of the symptoms.