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Showing papers in "Fertility and Sterility in 2006"


Journal ArticleDOI
TL;DR: MRgFUS treatment results in short-term symptom reduction for women with symptomatic uterine leiomyomas with an excellent safety profile, and the magnitude of improvement was greater than predicted.

458 citations


Journal ArticleDOI
TL;DR: The present study highlights the importance of an early diagnosis for women who suffer at physical, emotional, and social levels when they remain undiagnosed.

455 citations


Journal ArticleDOI
TL;DR: In vitro fertilization success rates with slow-frozen oocytes are significantly lower when compared with the case of IVF with unf Frozen oocytes, and pregnancy rates with VF appear to have improved and further studies will be needed to determine the efficiency and safety of this technique.

442 citations


Journal ArticleDOI
TL;DR: Given the fundamental role of sex hormones in the regulation of body composition, fuel homeostasis, and reproduction in humans, more emphasis should be placed on the potential role of androgen dysregulation in the pathophysiology of different obesity phenotypes and the metabolic syndrome.

406 citations


Journal ArticleDOI
TL;DR: There was no difference in the overall rates of major and minor congenital malformations among newborns from mothers who conceived after letrozole or CC treatments, however, it appears that congenital cardiac anomaly is less frequent in the letroZole group.

328 citations


Journal ArticleDOI
TL;DR: Analysis of mitochondrial DNA content in fertilized and unfertilized oocytes and embryos by real-time polymerase chain reaction (PCR) found it is critical to fertilization outcome and serves as an important marker of oocyte quality, explaining some cases of fertilization failure.

325 citations


Journal ArticleDOI
TL;DR: Many modifiable conditions exist in an ART setting that may aid in reducing the toxic effects of ROS, and the main objective of this review is to provide ART personnel with all the necessary information regarding the development of oxidative stress in anART setting.

307 citations


Journal ArticleDOI
TL;DR: Wide disparities exist in the quality, availability, and delivery of infertility services between the developed and developing nations of the world.

285 citations


Journal ArticleDOI
TL;DR: High ROS is an independent marker of MFI, irrespective of whether these patients have normal or abnormal semen parameters, and the inclusion of ROS measurement as part of idiopathic infertility evaluation is suggested.

284 citations


Journal ArticleDOI
TL;DR: Clinically significant OHSS still remains a limitation of multifollicular ovarian stimulation for IVF even with the use of GnRH antagonist protocols and the number of follicles can discriminate the patients who are at risk for developing OHSS, whereas E2 concentrations are less reliable for the purpose of prediction.

282 citations


Journal ArticleDOI
TL;DR: Sperm motility and concentration provide more accurate information than morphology (WHO and Tygerberg's criteria) during infertility evaluation, and redefining the reference values for concentration and morphology may significantly increase the importance of routine semen analysis.

Journal ArticleDOI
TL;DR: There has been a significant decline in 12-month infertility among married women in the United States, which cannot be explained by changes in the composition of the population from 1982-2002.

Journal ArticleDOI
TL;DR: African American women are more likely to seek infertility treatment after a longer duration of failed conception compared with Caucasian women, and African American, and Hispanic women areMore likely to have tubal factor infertility, a lower education level, and a lower household income compared with Caucasians.

Journal ArticleDOI
TL;DR: An association between early follicular serum AMH and ovarian response is demonstrated, but no association with pregnancy success is demonstrated.

Journal ArticleDOI
TL;DR: In this paper, the authors comprehensively reviewed and evaluated the direct and indirect costs of endometriosis in the United States and found that the indirect costs associated with reduced work productivity were considerable and appeared driven by hospitalizations.

Journal ArticleDOI
TL;DR: Vitrification with the Cryotop method is an efficient, fast, and economical method for oocyte cryopreservation that offers high rates of survival, fertilization, embryo development, and ongoing normal pregnancies, providing a new alternative for the management of female infertility.

Journal ArticleDOI
TL;DR: The peritoneal, ovarian, and deeply infiltrating endometriotic stromal cell lines described retain in vivo tissue markers, which may influence the capacity for proliferation and survival of these cells in the ectopic environment.

Journal ArticleDOI
TL;DR: There is no evidence of an increased risk for major malformations when metformin is taken during the first trimester of pregnancy, on the basis of the limited data available today.

Journal ArticleDOI
TL;DR: The presence of increased activated and degranulating mast cells in deeply infiltrating endometriosis, which are the most painful lesions, and the close histological relationship between mast cells and nerves strongly suggest that mast cells could contribute to the development of pain and hyperalgesia in endometRIosis, possibly by a direct effect on nerve structures.

Journal ArticleDOI
TL;DR: Acting through the brain, these hormones may serve as links between adipose tissue and the reproductive system to supply and regulate energy needs for normal reproduction and pregnancy.

Journal ArticleDOI
TL;DR: Progesterone indeed chemotactically guides mammalian spermatozoa at very low hormone concentrations, and the cumulus oophorus could be a potential place for sperm chemotaxis mediated by progesterone in vivo.

Journal ArticleDOI
TL;DR: Culture in low oxygen is associated with fewer perturbations in the global pattern of gene expression and more closely resembles that of the in vivo control embryos, providing rationale for culturing human embryos in the presence of 5%, rather than 20%, oxygen.

Journal ArticleDOI
TL;DR: This approach to analyze the secretome should not only further the understanding of embryo physiology but provide the basis for the development of noninvasive assays of embryo viability in human IVF.

Journal ArticleDOI
TL;DR: Vitrification technique yields the same implantation and pregnancy rate as slow-frozen blastocyst transfers, and slow growing embryos can be cryopreserved on day 6, because they yield a satisfactory survival, implantation, andregnancy rate.

Journal ArticleDOI
TL;DR: Investigation of whether important racial, ethnic, or socioeconomic status health disparities exist in infertility, impaired fecundity, or infertility treatment found that older women, non-Hispanic white women, and women who are more educated are more likely to have ever received treatment.

Journal ArticleDOI
TL;DR: Bovine is a good animal model for the development of human ovarian tissue cryopreservation protocols by equilibrium cooling procedures and vitrification is less efficient than equilibrium cooling, and at present, neither bovine nor pig can be considered relevant animal models for human tissue.

Journal ArticleDOI
TL;DR: Because SCD test values were correlated with embryo quality and blastocyst rate, the lack of correlation between sperm DNA fragmentation and pregnancy outcome in IVF might be due to embryo selection before transfer.

Journal ArticleDOI
TL;DR: Results demonstrate that DeltaPsi(m)(high) spermatozoa represents a subpopulation of sperm with high fertility performance because they have normal morphology, high motility values, and calcium ionophore-induced acrosome reaction, suggesting the importance of mitochondrial functionality for fertilizing capacity of human spermatoozoa.

Journal ArticleDOI
TL;DR: The P1/P2 ratio has a significant relationship to sperm fertilization ability and may be either a reflection of generalized abnormalities during spermiogenesis or an indication of protamine deficiency acting as a regulator or checkpoint of spermatogenesis.

Journal ArticleDOI
TL;DR: The recently introduced highly specific AIs have successfully treated pelvic pain and significantly reduced the lesion size and the side-effect profile of AIs administered in combination with an oral contraceptive or a progestin is remarkably benign.