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Showing papers in "Fertility and Sterility in 2011"


Journal ArticleDOI
TL;DR: Endometriosis impairs HRQoL and work productivity across countries and ethnicities, yet women continue to experience diagnostic delays in primary care, and a higher index of suspicion is needed to expedite specialist assessment of symptomatic women.

1,007 citations


Journal ArticleDOI
TL;DR: The clinical pregnancy rate per transfer was significantly greater in the cryopreservation group than in the fresh group, which strongly suggest impaired endometrial receptivity in fresh ET cycles after ovarian stimulation, when compared with FET cycles with artificialendometrial preparation.

555 citations


Journal ArticleDOI
TL;DR: Systematic collection and dissemination of international ART data allows patients, health professionals, and policy makers to examine and compare the impact of reproductive strategies or lack of them as markers of reproductive health.

498 citations


Journal ArticleDOI
TL;DR: The ovarian AFC and serum levels of AMH correlate with the ovarian primordial follicle number even after adjustment for chronological age.

473 citations


Journal ArticleDOI
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.

464 citations


Journal ArticleDOI
TL;DR: Women with PCOS exhibit an elevation in circulating CRP that is independent of obesity, which corroborates existing molecular evidence of the chronic low-grade inflammation that may underpin the pathogenesis of this disorder.

392 citations


Journal ArticleDOI
TL;DR: Vitrification is an efficient method to preserve oocytes, although more large controlled clinical trials are needed to strengthen this conclusion.

360 citations


Journal ArticleDOI
TL;DR: Morphology and aneuploidy are linked at the blastocyst stage, however, the association is weak, and consequently, morphologic analysis cannot be relied on to ensure transfer of chromosomally normal embryos.

341 citations


Journal ArticleDOI
TL;DR: These results provide the first epidemiologic evidence of an adverse effect of BPA on semen quality and similar dose-response associations were observed among men with environmental BPA exposure at levels comparable with those in the U.S population.

308 citations


Journal ArticleDOI
TL;DR: It is recommended that all women with PCOS be screened for dyslipidemia, including LDL-cholesterol and nonHDL-ch cholesterol determinations, for effective cardiovascular risk prevention.

303 citations


Journal ArticleDOI
TL;DR: It is suggested that higher age, smoking, alcohol consumption, and psychological stress were risk factors for semen quality and that health programs focusing on lifestyle and psychological health would be helpful for male reproductive health.

Journal ArticleDOI
TL;DR: Array-CGH is proved to be highly robust and specific when applied to rapid (24-hour) analysis of single cells biopsied from cleavage-stage embryos and is validated by reanalyzing the same embryos with another technique (e.g., FISH).

Journal ArticleDOI
TL;DR: The Fédération Internationale de Gynécologie et d'Obstétrique (FIGO) has designed the PALM-COEIN classification system for causes of AUB in the reproductive years.

Journal ArticleDOI
TL;DR: In this paper, age-specific serum anti-Mullerian hormone (AMH) values for women presenting to U.S. fertility clinics were determined for single-year median and mean AMH values with SDs.

Journal ArticleDOI
TL;DR: Careful definition of populations and classification of outcomes should optimize objective interpretation of research, allow objective assessment of future reproductive prognosis, and hopefully lead to improved clinical care of women initially identified to have a PUL.

Journal ArticleDOI
TL;DR: When differentiating between order and mode of conception, it seems that assisted reproductive technology plays a role in meanBirth weight and risk of low birth weight and preterm birth.

Journal ArticleDOI
TL;DR: In this paper, the authors estimate the incidence of endometriosis in an operative cohort of women seeking clinical care and in a matched population cohort to delineate more fully the scope and magnitude of the endometria in the context and beyond clinical care.

Journal ArticleDOI
TL;DR: This is the first report linking increased paternal BMI and clinical pregnancy and live birth rates after ART treatment, and further work to elucidate the mechanisms involved is required.

Journal ArticleDOI
TL;DR: The AMH overproduction in anovulatory polycystic ovaries (PCO) may therefore restrict folliculogenesis by an inhibitory effect on FSH sensitivity, thereby contributing to anovulation.

Journal ArticleDOI
TL;DR: Endometriosis symptoms such as chronic, incapacitating pelvic pain and infertility negatively and substantially impact the physical and mental health status, health-related quality of life, and productivity at work of women.

Journal ArticleDOI
TL;DR: Elevated follicular FFA levels are associated with poor COC morphology, and further work is needed to determine what factors influence follicularFFA levels and if these factors impact fertility.

Journal ArticleDOI
TL;DR: Endometriotic cyst formation and associated structural tissue alterations in apparently normal ovarian cortex may be a cause of reduced ovarian reserve and early diagnosis and intervention may be beneficial in women with endometriomas to protect their ovarian function.

Journal ArticleDOI
TL;DR: Rapidly advancing technologies are bringing new biomarkers to the clinical arena that promise to further reveal the complexities of the implantation process, and reliable methods to assess "receptivity" have not been established or adequately validated.

Journal ArticleDOI
TL;DR: The variability regarding the definition of poor ovarian responders appears to be striking, and the Bologna criteria developed by European Society for Human Reproduction and Embryology consensus in 2011 aim to define a consistent group of patients need to be tested through clinical trials.

Journal ArticleDOI
TL;DR: In an emergent setting, ovarian stimulation can be started at a random cycle date for the purpose of fertility preservation without compromising fertilization rates in letrozole cycles.

Journal ArticleDOI
TL;DR: Sperm DNA testing by the alkaline Comet assay is useful for both diagnosis of male factor infertility and prediction of IVF outcome.

Journal ArticleDOI
TL;DR: The mechanism of action of selective progesterone receptor modulators (SPRMs) is discussed and the preclinical and clinical efficacy and safety data supporting the potential use of these compounds for gynecologic indications are summarized.

Journal ArticleDOI
TL;DR: Although individual patient costs vary, these cost estimates developed from actual patient treatment experiences may provide patients with realistic estimates to consider when initiating infertility treatment.

Journal ArticleDOI
TL;DR: The effect of SDF on the probability of pregnancy can be calculated independent of the fertilization procedure or sperm origin; this can be overcome when good quality oocytes are employed.

Journal ArticleDOI
TL;DR: LESS provides an advantage over conventional multiaccess LPS in terms of postoperative pain and need for rescue analgesia, with similar perioperative outcomes.