Showing papers in "Fertility and Sterility in 2015"

TL;DR: It is shown that addition of LH in the FeTA system considerably enhances BPA minimum effective concentration in mouse and human but not in rat fetal testes, and this is the first report describing BPS and BPF adverse effects on a physiologic function in humans and rodents.

TL;DR: Recent technologies are now exploring transcriptional, translational, and post-translational events within the human follicle with the goal of identifying biomarkers that reliably predict oocyte quality in the clinical setting.

TL;DR: Vitamin D supplementation during pregnancy was associated with increased circulating 25(OH)D levels, birth weight, and birth length, and was not associated with other maternal and neonatal outcomes.

TL;DR: The results show that MPA is an effective oral alternative for the prevention of premature LH surge in woman undergoing COH and will help establish a new regimen for ovarian stimulation in combination with embryo cryopreservation.

TL;DR: Reproductive medicine specialists and obstetrician/gynecologists should promote more realistic views of the evidence-based realities of advanced maternal age pregnancy, including its high-risk nature and often compromised outcomes.

TL;DR: Sperm retrieval was higher for micro-TESE compared with cTESE and for cTese compared with TESA and forceless sperm extraction and aspiration in men with nonobstructive azoospermia.

TL;DR: Results suggest that even in a select group of patients that underwent fresh ET (P levels ≤1.5 ng/mL), endometrial receptivity may have been impaired by COS, and outcomes may be improved by using the freeze-all policy.

TL;DR: An increased amount of mtDNA in euploid embryos is related to poor implantation potential and may be indicative of reduced metabolic fuel during oocyte maturation.

TL;DR: Repeated 12-week courses of daily oral ulipristal acetate (5 and 10 mg) effectively control bleeding and pain, reduce fibroid volume, and restore QoL in patients with symptomatic fibroids.

TL;DR: The results suggest that TESTI-ICSI is an effective option to overcome infertility when applied to selected men with oligozoospermia and high ejaculated SDF levels.

TL;DR: PGS with the use of CCS technology increases clinical and sustained IRs, thus improving embryo selection, particularly in patients with normal ovarian reserve, and is associated with a significantly higher clinical IR.

TL;DR: CD138 IHC staining of endometrial biopsies in women with RPL provides increased sensitivity when screening for CE compared with H & E staining and morphological assessment alone, and deserves further investigation in a larger cohort.

TL;DR: Predictive models proved to be highly accurate in classifying male fertility status (fertile or infertile), with 82% sensitivity, and 99% positive predictive value, and DNA methylation patterns may be predictive of embryo quality during IVF.

TL;DR: The authors demonstrate long-term uterine viability after UTx, with continued menstruation and unaltered uterine artery blood flow and subclinical rejection episodes were effectively reversed by temporary increase of immunosuppression.

TL;DR: Antimüllerian hormone has weak association with implantation and clinical pregnancy rates in assisted reproductive technology but may still have some clinical utility in counseling women undergoing fertility treatment regarding pregnancy rates, particularly those with DOR.

TL;DR: A relationship between medical comorbidites and male semen production is identified, and men with diseases of the endocrine, circulatory, genitourinary, and skin diseases all showed significantly higher rates of semen abnormalities.

TL;DR: The physiology of orgasm and ejaculation is described, detailing the neuronal, neurochemical, and hormonal control of the ejaculation process.

TL;DR: There is currently no way of estimating donors' oocytes survival when considering baseline characteristics, storage time, or controlled ovarian stimulation parameters, and the probability of achieving a baby using vitrified oocytes increases progressively with the number of oocytes consumed.

TL;DR: Analysis of polar body DNA provides a window into the oocyte's genome and telomeres, which may enhance prediction of embryo developmental competence.

TL;DR: Ovarian cortex transplantation: time to move on from experimental studies to open clinical application.

TL;DR: The use of a population-based comparison group of subfertile births without ART demonstrated significantly higher rates of preterm birth and low birth weight in ART singleton births, but these differences are smaller than differences between ART and fertile births.

TL;DR: A classification of ureteral endometriosis is proposed that will allow the standardization of terminology and help to compare the outcome of different surgical treatment in randomized studies.

TL;DR: These data clearly demonstrate that preserving fertility by cryopreserving ovarian tissue is a successful and safe clinical option that can be considered for selected cancer patients.

TL;DR: In 95% of women with Asherman syndrome, a healthy uterine cavity was restored with hysteroscopic adhesiolysis, in 1-3 attempts, with a 28.7% recurrence rate of spontaneous IUAs.

TL;DR: Several circulating miRNAs are differentially expressed in the sera of women with endometriosis compared with controls, and the combination of serum let-7b, 7d, and 7f levels during the proliferative phase may serve as a diagnostic marker for endometiosis.

TL;DR: Cryopreserved ET is a strong independent risk factor for accreta among patients using IVF and/or ICSI, and a threshold endometrial thickness and a "safety window" of optimal peak E2 level are proposed for external validation.

TL;DR: A balanced discussion of the evidence for time-lapse monitoring and the proposed benefits compared with culture in a standard incubator and fixed time-point evaluation are uninterrupted culture, a flexible workflow in the laboratory, and improved embryo selection.

TL;DR: The injection of human SPIOs labeled CD133(+) BMDSCs in a murine model of Asherman syndrome confirms that these cells engraft around endometrial vessels, inducing proliferation of surrounding cells through paracrine molecules such as thrombospondin 1 and insulin-like growth factor 1.

TL;DR: The findings suggest both genetic and unique (nonshared) environmental influences on the complex etiology of endometriosis and support the hypothesis that genes have a strong influence on phenotypic manifestations of endometricriosis.