Showing papers in "Fertility and Sterility in 2020"

TL;DR: Severe acute respiratory syndrome–CoV-2 was not detected in the semen of patients recovering from CO VID-19 1 month after COVID-19 diagnosis and angiotensin-converting enzyme 2–mediated viral entry of SARS–Cov-2 into target host cells is unlikely to occur within the human testicle based on ACE2 and TMPRSS2 expression.

TL;DR: Markers of ovarian reserve include hormone levels and sonographically measured features of the ovaries that can be useful as predictors of oocyte yield following controlled ovarian stimulation and oocyte retrieval but are poor predictor of reproductive potential independently from age.

TL;DR: A mild COVID-19 infection is not likely to affect testis and epididymis function, whereas semen parameters did seem impaired after a moderate infection, which suggests no viral transmission during sexual contact and assisted reproductive techniques.

TL;DR: It is suggested that SARS-CoV-2 infection is unlikely to have long-term effects on male and female reproductive function and therefore procedures in which oocytes are collected and fertilized in vitro are associated with very little risk of viral transmission may be susceptible to exposure.

TL;DR: Current understanding of the effects of novel and prior coronaviruses on human reproduction, specifically male and female gametes, and in pregnancy is summarized.

TL;DR: Antioxidants do not improve semen parameters or DNA integrity among men with male factor infertility, and this study suggests that antioxidant treatment of the male partner does not improve in vivo pregnancy or live-birth rates.

TL;DR: Despite the widespread use of FET, the optimal protocol with respect to live birth rate, maternal health, and perinatal outcomes has yet to be determined and future practice regarding FET should be based on high-quality evidence, including rigorous controlled trials.

TL;DR: The treatment of unexplained infertility is by necessity empiric and for most couples, the best initial therapy is a course of ovarian stimulation with oral medications and intrauterine insemination followed by in vitro fertilization for those unsuccessful with OS-IUI treatments.

TL;DR: Gene expression and correlation between viral infectivity genes and age throughout the menstrual cycle and SARS-Cov-2 infection-related gene expression from endometrial transcriptomic datasets are determined.

TL;DR: OTC is highly effective at restoring fertility in sterilized patients, and prior exposure to chemotherapy should not be considered a contraindication.

TL;DR: DFI and HDS data can help clinicians to predict a man's fertility potential, to consider corrective therapeutic approaches, as well as to assess the risk to the offspring's health, in more than 25,000 aging men attending infertility clinics.

TL;DR: An overview of existing AI technologies in reproductive medicine is presented and the ultimate goal will be to apply AI tools to the analysis of all embryological, clinical, and genetic data in an effort to provide patient-tailored treatments.

TL;DR: The excessive presence of endometrial immune cells in CE patients may be involved in reducedendometrial receptivity and recurrent pregnancy failures.

TL;DR: Frozen embryo transfer, especially when coupled with preimplantation genetic testing allows for highly efficient single embryo transfers that translate to more singleton and therefore safer pregnancies, as well as healthier babies.

TL;DR: Fertility preservation gives patients with endometriosis a valid treatment option to help them increase their reproductive chances and performs surgery after ovarian stimulation for FP in young women and in older women, an individualized treatment should be considered.

TL;DR: Linzagolix significantly reduced EAP and improved QoL at doses of 75-200 mg and decreased BMD dose-dependently and the effects were maintained or increased at 24 weeks.

TL;DR: Vaginal radical trachelectomy had the highest clinical pregnancy rate, and minimally invasive approaches to fertility-sparing surgery had equivalent oncologic outcomes compared with an abdominal approach, in women desiring fertility preservation.

TL;DR: Cesarean scar defects (CSDs) should be suspected in women presenting with spotting, dysmenorrhea, pelvic pain, or infertility and a history of CS.

TL;DR: Evidence suggesting the role of mechanical stress on follicle growth in the ovary is summarized and recent use of ovary-damaging procedures to treat ovarian infertility is described, with initial success using mechanical disruption approaches.

TL;DR: The present review discusses the current literature regarding the association between systemic diseases and fertility, which may impact clinical outcomes or semen parameters, and male infertility has been suggested as a marker of future health.

TL;DR: An association exists between RPL and thyroid autoimmunity, but levothyroxine does not improve subsequent pregnancy outcomes, and women with RPL should be screened/treated for overt thyroid disease but not thyroid autoIMmunity.

TL;DR: Network meta-analysis showed that compared with placebo, surgical laparoscopy alone or GnRH agonist alone results in higher odds of pregnancy, and the evidence on the other interventions versus placebo or on the secondary outcomes including live birth, miscarriage, and adverse events is insufficient.

TL;DR: The author believes that finasteride and dutasteride induce a constellation of persistent sexual, neurological and physical adverse side effects, in a subset of men, which constitute the basis for Post-finasteride syndrome in individuals predisposed to epigenetic susceptibility.

TL;DR: The results of this study show a high degree of interembryologist and intraembryologist variability in scoring embryos, likely due to the subjective nature of traditional morphology grading, which may lead to less precise disposition decisions and discarding of viable embryos.

TL;DR: It is suggested that women with a thin EMT after obtaining a pregnancy by IVF should receive improved prenatal care to reduce the risk of delivering a SGA infant.

TL;DR: The LPS-derived oocytes increased the CLBR per ITT in a single ovarian cycle in patients fulfilling the Bologna criteria, and the DuoStim strategy is promising to manage this thorny population of patients, especially to avoid discontinuation after a first failed attempt.