Showing papers in "Fertility and Sterility in 2021"

TL;DR: The presence of male infertility is crucial to the health of patients and its effects must be considered for the welfare of society.

TL;DR: The PGT-A assay evaluated was highly prognostic of failure to deliver when an aneuploid result was obtained, and the trophectoderm biopsy had no detectable adverse impact on sustained implantation.

TL;DR: In this paper, five European centers present their collective experience of transplanting ovarian tissue in 285 women, focusing on surgical techniques and OTT outcomes, reproductive outcomes, the impact of chemotherapy before ovarian tissue cryopreservation (OTC), the risk of relapse, and endocrine resumption and longevity of transplanted tissue.

TL;DR: In this article, the attributes of mosaicism identified during preimplantation genetic testing for aneuploidy relate to clinical outcomes, in order to formulate a ranking system of mosaic embryos for intrauterine transfer.

TL;DR: The American Society for Reproductive Medicine Mullerian Anomalies Classification (2021) as discussed by the authors was proposed by the American Fertility Society (AFS) Task Force on Mullerian anomalies.

TL;DR: The purpose of this American Society for Reproductive Medicine Practice Committee report is to provide clinicians with principles and strategies for the evaluation and treatment of couples with infertility associated with obesity as mentioned in this paper.

TL;DR: In this paper, the authors investigated whether obstetric and perinatal outcomes in pregnancies differ after different frozen embryo transfer (FET) protocols and found that the risk of hypertensive disorders in pregnancy, postpartum hemorrhage, and cesarean section was significantly higher after programmed FET compared with natural cycle FET.

TL;DR: In this article, the authors investigated the association of endometrium preparation with perinatal outcomes and found that hormone replacement cycles were associated with an increased risk of postterm delivery and GDM.

TL;DR: In this article, the authors provide a critical review of the current methods and procedures for the evaluation of in fertile women, and it replaces the document of the same name, last published in 2015 (Fertil Steril 2015;103:e44-50).

TL;DR: In this paper, chronic inflammatory processes affecting the endometrium, as encountered in endometriosis, adenomyosis, and chronic endometritis, alter endometrial receptivity.

TL;DR: Oral administration of relugolix 40 mg demonstrated efficacy and safety comparable with those of leuprorelin in women with endometriosis-associated pain and was generally well tolerated.

TL;DR: In this paper, the authors discuss factors including the maternal immune system, genetics of the embryo and parents, anatomic factors, hematologic factors, reproductive tract microbiome, and endocrine milieu, which factors into embryo and endometrial synchrony.

TL;DR: In this paper, the development of IVM and IVG methods to support all stages of oocytes available within ovarian tissue will maximize the potential for all patients undergoing fertility preservation, and fertility restoration could be safely achieved in the laboratory either by in-vitro maturation (IVM) of oocyte aspirated from growing follicles or by the complete in vitro growth and maturation of primordial follicles to produce fertile metaphase II (MII) oocytes.

TL;DR: The results of in vitro maturation (IVM) investigations suggest the potential for wider clinical application as discussed by the authors, and the efficacy of IVM as reported in the published literature to date.

TL;DR: In this paper, the authors show that age at oocyte retrieval strongly affects reproductive prognosis after fertility preservation and suggest that women should be encouraged to decide before they reach the age of 35 years to significantly increase their chances of success.

TL;DR: In this article, the association between luteal serum progesterone levels and frozen embryo transfer (FET) outcomes was investigated, and it was shown that there may be a minimum clinically important level required to ensure an optimal endocrine milieu during embryo implantation and early pregnancy after FET treatment.

TL;DR: In this article, the impact of individualized luteal phase support (termed iLPS) in patients with low serum progesterone (P) levels compared with patients without LPS was analyzed.

TL;DR: A comprehensive assessment of the evolving literature concerning COVID-19 and male sexual and reproductive health, and guidance for patient counseling is provided in this paper, where the authors provide guidance for counseling.

TL;DR: Overall, female and male fertility, as well as IVF outcomes may be affected by short sleep duration, evening chronotype, or shift/night work schedules, however, the results were hardly comparable due to the heterogeneous study methodologies used.

TL;DR: In this paper, the effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation (SDF) rates in infertile men with clinical varicocele was evaluated.

TL;DR: Provider, patient, and legislative advocacy is warranted in the name of reproductive justice to expand insurance coverage and, in turn, maximize reproductive outcomes, which have been shown to improve as financial barriers are lifted.

TL;DR: Differential expression of plasma exosomal miRNAs may confer a risk of PCOS and may be helpful in distinguishing PCOS patients from controls, which could help in an epigenetic understanding of the pathophysiology ofPCOS.

TL;DR: Women with obesity experience a higher rate of miscarriage after euploid embryo transfer than women with a normal weight, suggesting that other mechanisms than aneuploidy are responsible for this outcome.

TL;DR: Older oocytes, when injected with sperm derived from samples with high SDF index, develop into embryos of poor quality that lead consequently to lower implantation and pregnancy rates and higher miscarriage rates, in intracytoplasmic sperm injection cycles from women with advanced maternal age.

TL;DR: In this article, the authors demonstrate the infectious nature of chronic endometritis (CE) in an inductive way by comparing the results of germ-oriented antibiotic therapy vs. no treatment in women with CE.

TL;DR: This study is the first to profile comprehensively sncRNAs in endometrial EVs from uterine fluid and identify sncRNA biomarkers ofendometrial receptivity and implantation success.

TL;DR: In this article, the authors compared the negative test results for chronic endometritis (CE) between subjects who did and did not receive antibiotic treatment, and found that broad-spectrum oral antibiotic therapy for 14 days is effective in the treatment of CE in >89.8% of cases.

TL;DR: It can be concluded that endometriosis organoids maintain epigenetic changes and are suggested as a novel preclinical model to determine the epigenetic mechanisms that underlie endometiosis.

TL;DR: In this paper, the authors present a definition of recurrent implantation failure that accounts for the effects of female age and anticipated blastocyst euploidy rates on cumulative implantation rates.

TL;DR: In this paper, the therapeutic effect of antibiotic treatment on pregnancy outcomes in the following frozen-thawed embryo transfer cycles of infertile women was investigated in a retrospective study, where a total of 640 women were included.