Journal•ISSN: 1369-0191
Fibrinolysis and Proteolysis
Churchill Livingstone
About: Fibrinolysis and Proteolysis is an academic journal. The journal publishes majorly in the area(s): Plasminogen activator & Fibrinolysis. It has an ISSN identifier of 1369-0191. Over the lifetime, 1576 publications have been published receiving 14841 citations.
Topics: Plasminogen activator, Fibrinolysis, Plasmin, Urokinase, Fibrin
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272 citations
TL;DR: The receptor, in addition to focusing the enzymatic activity at focal and cell-cell contacts, also regulates it by internalizing and degrading only the inhibited form of urokinase, so that the proteolytically active areas of the cell surface can be continuously monitored for their activity and their location modified.
260 citations
231 citations
TL;DR: It is concluded that the u-PA content of breast cancer tissue is an independent prognostic factor in predicting early relapse and can be selected within the stated risk groups defined by locoregional extension and hormone receptor status.
204 citations
192 citations