Showing papers in "Fitoterapia in 2010"

TL;DR: The present review highlights the current status of the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, size, entrapment efficiency, route of administration, biological activity and applications of novel formulations.

TL;DR: This article reviews many such structures and their related chemistry along with the recent advances in understanding mechanism of action and structure-function relationships of saponins at the molecular and cellular levels.

TL;DR: The aims of this review are to report putative positive effects of mushrooms consumption on cardiovascular diseases risk markers and to identify some putative bioactive compounds involved in these effects.

TL;DR: The present study attempts to identify the evolution of technical standards in manufacturing and the regulatory guideline development for commercialization of herbal drugs.

TL;DR: The medicinal uses of the mushroom C. militaris including its culture techniques are highlighted, aiming to draw sufficient attention of the researchers to the frontier research needs in this context.

TL;DR: The present review aims at reviewing the research works undertaken till date on this plant in order to provide sufficient baseline information for future works and for commercial exploitation of Tongkat Ali products with regard to consumer's safety.

TL;DR: It can be concluded that essential oils of industrial hemp, especially those of Futura, may have interesting applications to control spoilage and food-borne pathogens and phytopathogens microorganisms.

TL;DR: The poor and/or erratic oral bioavailability of polyphenolics can be improved using the PHYTOSOME delivery system, a strategy that enhances the rate and the extent of solubilization into aqueous intestinal fluids and the capacity to cross biomembranes.

TL;DR: The presented review summarizes the information concerning the botany, ethnopharmacology, phytochemistry, biological activity and toxicity of the C.occidentalis plant.

TL;DR: Harmine was the most effective against Proteus vulgaris, Bacillus subtilis and Candida albicans where inhibition zones ranged between 21.2 and 24.7 mm and the use of such compounds as new antimicrobial biorationals is recommended.

TL;DR: The results showed that the bioavailability of quercetin, kaempferol and isorhamnetin in rats was increased remarkably after oral administration ofGBP and GBS comparing with GBE, and the bioavailabilities of GBP increased more than that of GBS.

TL;DR: Alkaloids sanguinarine, chelerythrine, their dihydro derivatives, protopine and allocryptopine, and phenolics, gallic, protocatechuic, p-hydroxybenzoic, m-Hydroxybenzosic, gentisic,p-coumaric, caffeic, ferulic and sinapic acids were determined in extracts prepared from M. cordata aerial part, seeds, and seed capsules.

TL;DR: The studies showed that LT1 presented significant antitumor bioactivities on Sarcoma180 solid tumor cell implanted in BALB/c mice, which implies thatLT1 could be potentially applied as a natural antitumors drug.

TL;DR: Honey and its extracts were able to inhibit edema and pain in inflammatory tissues as well as showing potent inhibitory activities against NO and PGE(2) in both models, indicating honey is potentially useful in the treatment of inflammatory conditions.

TL;DR: The data yielded so far contribute to the understanding of the mode of action of this phytocomplex on nerve tissue under normal and pathological experimental conditions and provide a rational basis for the practical use of BEO in complementary medicine.

TL;DR: The results indicate that TSS could inhibit thrombosis by both improving the anticoagulation activity and inhibiting PAG action, suggesting that T SS from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.

TL;DR: The structure of the new 3'-geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone was elucidated by means of spectroscopic methods and morusin was the most potent with an IC(50) value of 0.64 μM against HeLa cells.

TL;DR: The results suggest that PAP is involved in immunomodulatory effects leading to the exploration for PAP as a potential immunostimulant.

TL;DR: Inhibition of cell growth and H(+)-efflux by test compounds suggests that their antifungal properties are related to their inhibitory effects on H( +)-ATPase.

TL;DR: In this review, emphasizing the molecular, cellular, and functional bases of therapy, data appearing in the peer-reviewed literature and focussing the main therapeutic applications of pycnogenol will be summarized and critically evaluated.

TL;DR: It was demonstrated that intraperitoneal administration of 1 at a dose of 5, 10, 50 and 100 mg/kg produced significant dose-dependent inhibition of paw edema induced by carrageenan and suppressed granulomatous tissue formation in cotton pellet-induced granuloma test.

TL;DR: It seems to be a continuum of the beneficial effect of coffee consumption on liver enzymes, cirrhosis and hepatocellular carcinoma, and experiments with animal models of liver damage are needed to evaluate the possible causative role of coffee but also its action mechanism.

TL;DR: Flavonoids and phenylpropanoids are the major compounds of all the organs of this plant and showed no relation to enzyme inhibition in the test models.

TL;DR: In FD mice, berberine reduced mouse weight gain and food intake and serum glucose, triglyceride, and total cholesterol levels accompanied with a down- regulation of PPARgamma expression and an up-regulation of GATA-3 expression.

TL;DR: The results suggested that the activation of PPARgamma and the modulation of metabolism-related genes were likely involved in the anti-diabetic effects of emodin.

TL;DR: The findings demonstrate the excellent pharmacological potential of mahanimbine to prevent obesity and the observed antiobesity and antihyperlipidemic activities of these extract are correlated with the carbazole alkaloids present in them.

TL;DR: This review is an attempt to evaluate critically the role of SCAR markers in authentication of medicinal herbs used in traditional formulations by converting RAPD amplicons into Sequence Characterized Amplified Region (SCAR) markers.

TL;DR: The changes in blood urea nitrogen and serum creatinine revealed that CPS-2 could significantly relieve renal failure caused by fulgerizing kidney, and its structural characteristics were investigated by PMP pre-column derivation, periodate oxidation, methylation analysis, FTIR and NMR spectroscopy.

TL;DR: The presence of coumarinolignans as major chemical constituent and the reduced dry and wet weight of cotton pellet granuloma in mice suggests that cleomiscosin A is an important constituent of MHN responsible for anti-inflammatory activity.

TL;DR: From propolis samples from Kenya, two new arylnaphtalene lignans were isolated, tetrahydrojusticidin B 1 and 6-methoxydiphyllin 2, along with four known phenolic compounds 5-8, found for the first time in propolis, and the structures of the compounds were elucidated based on their spectral properties.