Showing papers in "Fitoterapia in 2011"

TL;DR: The aim of this review is to discuss both the antioxidant and prooxidant effects of flavonoids.

TL;DR: Gallocatechins of green tea and curcuminoids of ginger are the presently favoured polyphenols for a possible future use in co-medication with antibiotics and standard anticancer drugs and the main targets were found to be COX 1+2, NF-κB, and membrane glycoproteins that belong to the ATP-binding cassette (ABC) transporter family.

TL;DR: The present study reviews the traditional therapeutic uses of orchidaceous preparations with its recent advances in pharmacological investigations that would be a useful reference for plant drug researches, especially in orchids.

TL;DR: This review describes how the incorporation of microbial metabolism as an important variable in the evaluation of the final bioactivity of botanicals strongly increases the relevance and predictive value of the outcome.

TL;DR: BPF inhibited HMG-CoA reductase activity and enhanced reactive vasodilation thus representing an efficient phytotherapeutic approach in combating hyperlipemic and hyperglycaemic disorders.

TL;DR: 10-gingerol, 8-shogaol and 10- shogaol inhibit COX-2 but notCOX-1, which can explain, in part, the anti-inflammatory properties of ginger.

TL;DR: The presented review summarizes information concerning the morphology, ethnopharmacology, phytochemistry, and biological activities of caper plants.

TL;DR: The principles of accuracy (relationship between experimental and true value), precision, precision, and reliability in the quantitation of phytochemicals in natural products are discussed.

TL;DR: The results suggest that PA possesses potent anti-inflammatory activity, which may be mediated, at least in part, by down-regulating the mRNA expression of a panel of inflammatory mediators including TNF-α, IL-1β, iNOS and COX-2.

TL;DR: It is reported that the COC combination could increase the plasma level, slow elimination rate, exert a more robust therapeutic effect than any one or two of the three individual compounds by hitting multiple targets in a rat model of HI.

TL;DR: In this paper, three extracts of different polarities of Glycyrrhiza glabra L. leaves were characterized and evaluated for their antioxidant, anti-genotoxic and anti-inflammatory activity.

TL;DR: The results confirmed that the four alkaloids imperialine, chuanbeinone, verticinone and verticine may be the active ingredients of the Bulbus F. Cirrhosae (BFC).

TL;DR: It is shown for the first time in vivo that CA and CS differentially regulate the expression of inflammation-associated genes, thus demonstrating the pharmacological basis for the anti-inflammatory properties reported for CA andCS.

TL;DR: Beauvericin showed cytotoxicity against PC-3, PANC-1, and A549 with IC(50) value of 49.5 ± 3.8, and exhibited anti-bacterial activity towards methicillin-resistant Staphylococcus aureus and Bacillus subtilis.

TL;DR: The present review has summarized the information concerning the occurrence, botanical description, ethanopharmacology, medicinal uses, biological activities and toxicological studies on this plant.

TL;DR: Variability in the composition of essential oil was clearly dependent on the geographic location of the growing plant, and the need for further research of this herb and its products is suggested.

TL;DR: The results showed that LPS/INF-γ increased NO production in RAW264.7 macrophages, whereas L-NAME and CE curtailed it, and it could be concluded that CE is potentially useful in treating inflammation through the inhibition of COX and RNS but not ROS.

TL;DR: A rapid, simple and sensitive method for quantitative analysis of quercetin-3-O-β-D-glucuronide in P. perfoliatum L. was developed using high performance liquid chromatography (HPLC) coupled with photodiode array detection and validated for linearity, repeatability, limit of quantification (LOQ), precision and robustness.

TL;DR: In all systems, T. polium extract exhibited excellent activity potential than that of S. iberica, and a significant protection was observed for native super coiled DNA of pBR322 plasmid DNA.

TL;DR: The hepatoprotective effects of polyprenols from Ginkgo biloba L. leaves were evaluated against carbon tetrachloride induced hepatic damage in Sprague-Dawley rats and the effects of GBP were not significantly different from those of the standard drug Essentiale.

TL;DR: A lupin seed γ-conglutin-enriched preparation tested in a glucose overload trial with both murine models and adult healthy volunteers showed a dose-dependent significant decrease of blood glucose concentration, which confirmed previous findings obtained with the purified protein.

TL;DR: The alkaloids cyclotropine, dihydroaposcopolamine, 6,7-dehydrohyoscyamine and 4'-hydroxylittorine are reported for the first time for the genus Datura and 6, 7-deHydrotropine for the family Solanaceae.

TL;DR: The standardized EtOAc, MeOH and 70% EtOH extracts of Tridax procumbens aerial parts showed significant inhibition of rat paw edema at a medium dose of 200mg/kg and the EtOAC extract was the most active.

TL;DR: Ethyl acetate fraction of ethanolic extract of Z. armatum could significantly decrease acetic acid-induced writhing numbers, and suppress formalin induced licking times in the first phase at the highest dose and in the second phase at all tested doses, showing powerful antinociceptive activity.

TL;DR: In vitro experiments showed that extracts of Aronia melanocarpa or seeds of Vitis vinifera prolonged clotting time and decreased the maximal velocity of fibrin polymerization in human plasma, which gives hopes for development of diet supplements, which may be preventing thrombosis in pathological states.

TL;DR: In this article, polyphenolics extracted from yaupon holly (Ilex vomitoria, Aquifoliaceae) leaves were investigated in human colon cells for their chemopreventive and anti-inflammatory activities.

TL;DR: The study examined the antiinflammatory and antinociceptive effects of the sesquiterpene (-)-α-bisabolol (BISA) and suggested that BISA may be an topical anti inflammatory and visceral antiniceptive agent.

TL;DR: A new labdane-diterpene, viteagnusin I, together with 23 known phytoconstituents were isolated from the fruits of Vitex agnus-castus L, and their structures characterized by spectroscopic methods.

TL;DR: Berberine significantly up-regulated the declined cyclin-dependent kinase 9, cyclin T1 mRNA and protein expression in diabetic rat liver and the effects of berberine on up-regulation of P-TEFb expression, antioxidant and antilipid peroxidation may be related to its protective potential on diabetes.

TL;DR: In this article, the authors examined if Kaempferia galanga yielded an anti-TB molecule, ethyl p-methoxycinnamate (EPMC), which was shown to inhibit M. tuberculosis.