Showing papers in "Fitoterapia in 2022"

TL;DR: This review gives an account of the current knowledge on the chemical constituents, biological activity and pharmacological properties of Securinega suffruticosa, an indolizidine alkaloids containing a unique tricyclic structure.

TL;DR: In this article , the authors summarized the types, active ingredients, pharmacological effects, extraction methods and applications of propolis flavonoids, the aim was to provide the theoretical basis for further research and development of Propolis Flavonoids.

TL;DR: In this article, a chemical investigation on one kiwi endophytic fungi, Fusarium tricinctum, resulted in the isolation of nine new imidazole alkaloids, fusaritricines A-I (1, 3, 9, and 13), with MIC values between 25 and 50μg/mL.

TL;DR: In this paper , a chemical investigation on one kiwi endophytic fungi, Fusarium tricinctum, resulted in the isolation of nine new imidazole alkaloids, fusaritricines A-I (1-9) together with seven known analogues (10-16).

TL;DR: Wang et al. as mentioned in this paper showed that erianin can specifically inhibit the activity of human pyruvate carboxylase, and the purified human p-carpylase can specifically bind to the activity probe of eriansin, and explored the anti-tumor signal pathway regulated by erians in several cell lines.

TL;DR: In this article , the structural-activity relationship of chemical modifications on the dammarane-type skeleton and the C-17 side chain of ginseng has been investigated, and it has been shown that certain structurally modified derivatives exhibit satisfactory pharmacological activity.

TL;DR: In this paper, the authors investigated how the microbial metabolite of quercetin, 3-(3-hydroxyphenyl)propionic acid (3HPPA), impact monocyte adhesion to endothelial cells.

TL;DR: In this paper , six monoterpene indole N-oxide alkaloids and their parent alkaloid were obtained from the stem bark of Tabernaemontana corymbosa and their structures and absolute configurations were elucidated by extensive spectroscopy, quantum chemical calculations and DP4+ probability analyses.

TL;DR: In this article , the authors investigated how the microbial metabolite of quercetin, 3-(3-hydroxyphenyl)propionic acid (3HPPA), impact monocyte adhesion to endothelial cells.

TL;DR: In this article , three cycloartane triterpenoids, commikuanoids A-C (1, 3), together with four known compounds 4-7, were isolated from the resin of Commiphora kua.

TL;DR: In this article , a new furanocoumarin named Rutagrarin (1) along with 14 known compounds (2-15) from the aerial parts of R. graveolens and elucidated their chemical structures via various spectroscopy.

TL;DR: In this paper , four prenylated phloroglucinol derivatives (+)-erectumol I (1a), (--erectusol I(1b), (-)-ethumol II (2a), and (+)-ethusol II(2b) were isolated from the methanol extracts of the whole plants of Hypericum erectum.

TL;DR: Artemetin (ART) has been examined in vitro against lipid oxidation and its impact on cancer cells has been explored as mentioned in this paper , showing that ART significantly reduced viability and modulated lipid profile in cancer Hela cells at the dose range 10-50 μM after 72 h of incubation.

TL;DR: In this article , the authors investigated the ability of six prenylated prerocarpans, stilbenoid, and a new dimeric flavonoid, lespebicolin B, from stem bark as well as two 3-O-rutinosides and a mixture of 3O-β-D-glucosides of quercetin and kaempferol from flowers of Lespedeza bicolor to inhibit HSV-1 replication in Vero cells.

TL;DR: Tabernaecorymine A, an 18normonoterpenoid indole alkaloid with conjugated (E)-3-aminoacrylaldehyde fragment was obtained from the stem bark of Tabernaemontana corymbosa as discussed by the authors .

TL;DR: In this article , seven new 2-(2-Phenethyl) chromone derivatives (1-7) were identified from agarwood originating from Aquilaria agallocha Roxb and their structures were determined mainly by high-resolution electrospray ionization mass spectrometry (HR-ESI-MS) and nuclear magnetic resonance (NMR) analysis.

TL;DR: In this paper , eight sesquiterpenoid dimers, artatrovirenolides A-H (1-8), along with three known analogues (9-11), were isolated from Artemisia atrovirens by using the LC-MS guided isolation.

TL;DR: Wang et al. as discussed by the authors used NMR, MS, UV, and IR spectral data to determine the structure of highland barley Monascus pigments, which showed important inhibition of pancreatic lipase activity and decreased significantly FFA-induced lipid accumulation in HepG2 liver cells.

TL;DR: In this article , three novel alkaloids, identified as (E)-N-((2R)-3-(2,5-dihydroxy-4-((3,4,5)-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-hydroxypropanoyl)-

TL;DR: In this article, three novel alkaloids, identified as (E)-N-((2R)-3-(2,5-dihydroxy-4-((3,4,5)-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-hydroxypropanoyl)-

TL;DR: In this paper , three new chlorinated orsellinic aldehyde derivatives, orsaldechlorins A -C (1-3), and a naturally new brominated ORSinic acid (7), along with ten known biosynthetically related phenolic derivatives, were identified from the Beibu Gulf coral-derived fungus Acremonium sclerotigenum GXIMD 02501.

TL;DR: One new xanthone, griseophenexanthone A (1), one new benzophenone, digriseophene A (2), and 14 previously reported compounds were isolated from the culture of Corydlis tomentella sp. ct-28 as discussed by the authors .

TL;DR: Ferruginol (Fer) is an amonomeric compound isolated from a traditional Chinese herb, which has shown potent neuroprotective effects in both in vitro and in vivo Parkinson's disease (PD) models.

TL;DR: Seventeen triterpenoids including four lanostane triterpoids (1-3 and 5) were isolated from the fruiting bodies of Ganoderma lucidum by various chromatographic techniques as discussed by the authors .

TL;DR: In this article , a pre-generated plant extract library was used to identify bioactive components and potential therapeutic molecules from plants, and botanicals were subjected to LC-MS/MS-based molecular networking to determine their chemical composition and quantify already known metabolites.

TL;DR: In this article , four undescribed compounds including one germacrane-type sesquiterpene lactones (1), alkaloid (2), along with two neolignans (3-4) were isolated from Elephantopus scaber L. Their structures and absolute configurations were elucidated unambiguously by means of 1D and 2D NMR spectroscopic data analysis, and quantum chemical electronic circular dichroism calculations, as well as single-crystal X-ray crystallography.

TL;DR: In this article , 16 guaiane-type sesquiterpenoids were isolated from Stellera chamaejasme L. 1 represents the first example of 2,3-seco-guaiane sesQUERPoid with a 5/6/7 bridged ring system.

TL;DR: Ferruginol (Fer) is an amonomeric compound isolated from a traditional Chinese herb, which has shown potent neuroprotective effects in both in vitro and in vivo Parkinson's disease (PD) models as mentioned in this paper .

TL;DR: In this article , three sesquiterpene phenol dimers, bidysoxyphenols A-C (2-C), along with two known compounds, namely SESQUERPENE phenol (1) and ionone derivatives (5), were isolated from the leaves of Dysoxylum parasiticum (Osbeck) Kosterm.

TL;DR: In this article , a review provides profiles of the advances in the distribution, chemistry, and biological activities of natural phthalides in 2016-2022, with a focus on n-butylphthalide, a phthalide monomer used to cure ischemic stroke.