Showing papers in "Future Journal of Pharmaceutical Sciences in 2021"

TL;DR: In this article, an attempt has been made to compile the exploration of natural phenolic compounds with major emphasis on flavonoids and their therapeutic potential too, and an overview of flavonoid compounds to use them as a potential therapeutic alternative in various diseases and disorders.

TL;DR: In this paper, the HPTLC densitometric analysis of the methanolic extract of Fumaria parviflora (whole plant) was carried out using CAMAGHPTLC system, and the results were obtained in the form of chromatograms (scanned at the wavelength of 254 nm and 366 nm) representing several peaks.

TL;DR: In this article, a review article attempts to enlist medicinal plants which have been reported to be effective in the treatment of wounds and discuss plant constituent-based wound dressings have also been discussed systematically including patented formulations reported by different inventors.

TL;DR: In this paper, molecular docking studies of the phytocompounds of Citrus medica and Zingiber officinale were done to find out whether these compounds could inhibit the receptor binding of SARS-CoV-2 spike protein (S protein) as well as the angiotensin-converting enzyme 2 (ACE-2), as evidenced from their docking into binding/active sites.

TL;DR: In this paper, an extensive search was conducted on the clinical trial registries around the world to identify all the trials reporting information regarding the use of corticosteroids in COVID-19.

TL;DR: In this paper, the structure activity relationship (SAR) of pyrimidine derivatives as anticancer agent from the last decade has been investigated and a review intends to assist in the development of more potent and efficacious anticancer drugs with Pyrimidine scaffold.

TL;DR: The triazole nucleus is one of the most important heterocycles which has a feature of natural products as well as medicinal agents as discussed by the authors and is abundantly present in most medicinal compounds.

TL;DR: In this paper, a study was carried out to evaluate the antioxidant effect and possible bioactive components present in the aqueous methanol fraction of Hibiscus asper leaves.

TL;DR: In this paper, a review of the use of microneedles in drug delivery is presented, which includes various fabrication materials and methods used for MN synthesis, and the pharmacokinetics of MNs, including permeation, absorption and bioavailability enhancement.

TL;DR: A review of the literature on the phytochemical and scientifically proven toxicological profiles of A. vera and A. ferox can be found in this article, where the authors provide beneficial information about phytochemistry and toxicity of Aloe vera.

TL;DR: Piperidine is an essential heterocyclic system and a pivotal cornerstone in the production of drugs as discussed by the authors, and Piperidine byproducts showed several important pharmacophoric features and are being utilized in different therapeutic applications.

TL;DR: Pyridine scaffolds have been detected in most relevant drug molecules that included pyridine provided a great possibility for treatment as mentioned in this paper, and the heterocyclic compounds particularly pyrinedine displayed clinical and biological implementation.

TL;DR: In this article, the assessment of antioxidant potential as well as free radical scavenging activity such as DPPH, hydroxyl radical, hydrogen peroxide, and superoxide anion radical assay of Chlorella vulgaris Beyerinck [Beijerinck] (BUACC25) isolated from marine habitat have been investigated.

TL;DR: This review is aimed at identifying ethnomedicinal herbs available in Africa that could be used for the discovery and development of a drug for the prevention, treatment, and management of the novel coronavirus disease 2019.

TL;DR: The use of polymer blends represents a valuable and under-utilized resource in addressing a diverse range of drug delivery challenges, such as bioavailability enhancement and the demand for enabling excipients.

TL;DR: Citric acid (CA) is a universal plant and animal-metabolism intermediate and is widely used in many sectors including foodstuffs, beverages, pharmaceuticals, nutraceuticals, and cosmetics as a flavoring agent, sequestering agent, buffering agent, etc as mentioned in this paper.

TL;DR: The role of unprocessed A. vera gel homogenate is justified in preventing tissue damage and in the downregulation of TNF-α and Cox-2 gene expressions for the immune-modulation of inflammatory arthritis condition.

TL;DR: In this paper, the authors consolidated the insights pertaining to new drug development against drug-resistant microbes, including drug discovery void, gene paradox, transposon mutagenesis, vitamin biosynthesis inhibition, use of non-conventional media, host model, target through quorum sensing, genomic-chemical network, synthetic viability to targets, chemical versus biological space, combinational approach, photosensitization, antimicrobial peptides and transcriptome profiling.

TL;DR: In this article, a review of pharmacists' contributions during the COVID-19 pandemic is presented, focusing on their collaborative efforts and dedication regarding their limitations during the situation and view the prospects of pharmaceutical care services in post-pandemic period.

TL;DR: A review of reports on chemical and pharmacological investigations carried out with jackfruit has been presented in this paper, which shows that the fruit contains a huge amount of phytochemicals such as phenolics, flavonoids, terpenoids, steroids, glycosides, saponins, alkaloids, and tannins which exhibit antioxidant properties.

TL;DR: In this paper, an experimental design based on a central composite design of two key components of the RP-HPLC method (mobile phase and pH) is presented, which can potentially lead to a more robust/rugged method due to emphasis on risk assessment and management than traditional or conventional approach.

TL;DR: In this article, molecular docking simulation studies revealed 9 phytocompounds as having the top 5 binding affinities towards SARS-CoV-2 Mpro and furin.

TL;DR: In this article, the potential drugs suggested to be repurposed to be utilized in the treatment of COVID-19 patients like lopinavir-ritonavir, ribavirin, baloxavir marboxil, favipiravirus, remdesvir, umifenovir, and ruxolitinib.

TL;DR: In this article, the authors developed a protein/peptide-loaded nanoparticle-based delivery system, which can efficiently deliver therapeutic molecules to the lung via pulmonary delivery by using ionic gelation method.

TL;DR: Although UA and BA possess several therapeutic properties, their long-term usage can cause mild toxicity in their users, and this study paves way for evaluating the optimum effective and safe dose of these phytocompounds.

TL;DR: In this paper, a review article has been conceived and made as a hybrid of the review of the selected papers advertised recently and produced in the interest of the COVID-19 situation, and in silico work done by the authors.

TL;DR: In this paper, a review aimed to highlight ethnomedicinal uses, phytochemical status, and pharmacological properties of Chenopodium ambrosioides L. is presented.

TL;DR: In this paper, the authors evaluated the individual in vivo potential to achieve brain targeting using chitosan-based polymeric nanoparticles and mucoadhesive microemulsion systems through ionic gelation and water titration.

TL;DR: A review of traditional uses, phytochemistry, and pharmacological activities of the C. tinctorium A. Rich can be found in this paper, where the authors summarized the traditional uses and phytochemical properties of the plant.

TL;DR: A review of 51 Nigerian medicinal plants was presented in this paper, where the major classes of bioactive compounds indicated to be responsible for the anticancer activity include polyphenols, flavonoids, alkaloids, saponins, triterpenes, tannins, and quinones.