Showing papers in "Heart Failure Clinics in 2016"

TL;DR: Patients with the most advanced disease and worst prognosis can be identified using iterative, integrated clinical assessment of symptom burden, effort intolerance, and cardiac dysfunction.

TL;DR: The literature on epidemiology, mechanisms, and risk factors of postoperative atrial fibrillation are reviewed, with a subsequent focus on the therapeutic interventions and guidelines regarding management.

TL;DR: Treatment for Cardiac Syndrome X includes life-style modification, anti-anginal,anti-atherosclerotic, and anti-ischemic medications, and non-pharmacological options include cognitive behavioral therapy, enhanced external counterpulsation, neurostimulation, and stellate ganglionectomy.

TL;DR: This work linked a biorepository to identify biomarkers for the diagnosis and prognosis and to investigate the genetic basis as well as disease-related factors of Takotsubo syndrome.

TL;DR: As the risk for CAD is largely understood to be inherited, further genetic testing should play a role in preventative treatment of the disease.

TL;DR: The limited data available to date suggest that frailty is highly prevalent in patients with advanced HF and appears to provide prognostic information not captured by traditional risk assessment.

TL;DR: Risk factors that increase sympathetic tone and/or catecholamine sensitivity may render individuals particularly susceptible to takotsubo syndrome during episodes of acute stress.

TL;DR: Molecular imaging is a promising approach for identifying patients at increased risk of recurrence of Takotsubo syndrome and is helpful in the differential diagnosis with other disease states.

TL;DR: An individualized close-follow-up is of utmost importance to avoid any relapse and not to oversee any impeding complications in light of dynamic processes in myocardial stunning.

TL;DR: A simplified examination of AF risk factors, including emerging genetic risks, is presented, highlighting the need for an urgent attention to the problem.

TL;DR: This article provides a contemporary review of the clinical features of the takotsubo syndrome and discusses hallmark elements that distinguish this novel acute cardiac condition from the more common acute coronary syndrome.

TL;DR: Choice of pharmacologic therapy depends on whether the goal of treatment is maintaining sinus rhythm or tolerating AF with adequate control of ventricular rates, and on the side effect profile, and the authors should select best antiarrhythmic therapy, individualized to the patient.

TL;DR: The putative role of a switch in b-adrenoceptor signalling resulting in negative inotropy remains uncertain, and downregulation of noncritical cellular functions may offer some protection in preventing irreversible cellular necrosis.

TL;DR: The higher level of cardiac markers in males with TTS may be related to the greater frequency of physical stress before the onset of TTS, which may lead to preventive/therapeutic means against this life-threatening disease.

TL;DR: How translation of experimentally derived understanding of the rotors may find its way into the clinic is discussed, focusing on studies analyzing spatial distribution of DF in the atria of patients with paroxysmal versus persistent AF and how that knowledge might contribute to improve the outcome of AF ablation procedures.

TL;DR: Both acute myocardial infarction and takotsubo syndrome seem to exhibit a temporal preference in their onset, characterized by variations according to time of day, day of the week, and month of the year, although with both analogies and differences.

TL;DR: Temporary percutaneous mechanical circulatory support is increasingly used in patients with cardiogenic shock as a bridge to recovery or further definitive therapy, and the evidence supporting their continued use is reviewed.

TL;DR: The published studies on surgical and percutaneous approaches to LAA closure are reviewed, focusing on stroke mechanisms in AF, LAA structure and function relevant to stroke prevention, practical differences in procedural approach, and clinical considerations surrounding management.

TL;DR: The role of functional polymorphisms in relevant candidate genes, such as α1-, β1-, and β2-adrenergic receptors; G protein-coupled receptor kinase 5; and estrogen receptors, are still unclear.

TL;DR: In this article, the authors summarized the current evidence regarding the effectiveness of various medical therapies and revascularization strategies in patients with diabetes mellitus (DM) and showed the superiority of coronary artery bypass grafting over multivessel percutaneous coronary intervention.

TL;DR: It is hoped that improved understanding of the pathophysiologic processes of the initiation and maintenance of AF will refine target selection during ablation and improve long-term procedural efficacy, particularly in patients with persistent and long-standing persistent AF.

TL;DR: In severe cases with refractory cardiogenic shock, early treatment with mechanical support using venoarterial extracorporeal membrane oxygenation or a LV assist device should be considered.

TL;DR: The history and new insights of takotsubo syndrome are reported based on the achievements that Japanese researchers have contributed and the evidence originally presented from Japan is summarized.

TL;DR: Stress testing remains the cornerstone for noninvasive assessment of patients with possible or known coronary artery disease (CAD) and the most important application of stress testing is risk stratification.

TL;DR: The current understanding of Liver disease in heart failure is reviewed and a framework for approaching liver disease in the advanced heart failure population is provided.

TL;DR: All patients with complex multivessel coronary artery disease should be reviewed by a heart team including a cardiac surgeon and interventional cardiologist.

TL;DR: Developments in these areas may result in more equitable distribution and expansion of the donor pool and improved quality of life and survival for heart transplant recipients.

TL;DR: Overall, the safety and efficacy of AVJ ablation is high with a majority of the patients reporting significant improvement in symptoms and quality-of-life measures.

TL;DR: As atrial fibrillation substantially increases the risk of stroke and other thromboembolic events, most AF patients require appropriate antithrombotic prophylaxis, and risk has to be weighed individually.

TL;DR: A focused update on contemporary management strategies pertaining to antiplatelet, antithrombotic, and anti-ischemic therapies and to revascularization strategies in patients with ACS is provided.