Showing papers in "Immunopharmacology and Immunotoxicology in 1984"
TL;DR: PLA selectively modulates macrophage activity without influencing NK activity, and acts as a ‘spatially aggregating force’ to suppress natural killer cell activity.
Abstract: Intraperitoneal injection of PLA into C57BL/6 mice induced high levels of macrophage-mediated cytostatic activity. Maximal cytostatic activity was found 3 days after injection of 100 mg/kg of PLA. In contrast, natural killer cell activity was not affected by PLA. Thus, PLA selectively modulates macrophage activity without influencing NK activity.
22 citations