Indian Journal of Cancer 

About: Indian Journal of Cancer is an academic journal published by Medknow. The journal publishes majorly in the area(s): Cancer & Breast cancer. It has an ISSN identifier of 0019-509X. Over the lifetime, 2873 publications have been published receiving 26194 citations. The journal is also known as: The Indian Journal of Cancer.

Cancer of the stomach.

Abstract: Introduction and methods epidemiology - demographic aspects histology presentation and investigations treatment and survival IVA unresected cases prognostic factors unusual tumours lymphoma, M.S.Hockey and J.C.Crocker standardized rates census and inter-censal populations immunohistochemistry of gastric lymphoma.

Affordable image analysis using NIH Image/ImageJ.

Abstract: CMYK47 Sir, The contribution of scientific technology in the field of histopathology and lab medicine is well recognized. Image analysis is one such division in which many researchers and practicing pathologists have used scientific technology to good advantage. Currently there are many systems available to an anatomic pathologist for the purpose of image analysis in immunohistochemistry (IHC) and for nuclear morphometry. Many of these systems, however, require expensive software and hardware attachments for image acquisition, analysis and storage. Consequently, a costeffective alternative for image analysis would be a welcome tool for pathologists and researchers alike. In this connection, “ImageJ” is a freely available java-based public-domain image processing and analysis program developed at the National Institutes of Health (NIH). Currently, ImageJ’s Macintosh platform counterpart, “NIH Image” is widely used in biologic research.

Epidemiology of childhood cancer in India.

Abstract: There has been enormous progress in the treatment of childhood cancer in the developed world and the epidemiology in these countries is well described. Hitherto, there has been no attempt to systematically study the burden of childhood cancer in India or to understand how the occurrence and outcome of the disease varies across the country. We have reviewed the epidemiology (incidence, survival, and mortality) of childhood cancer across different population-based cancer registries in India and also compared it with data from the resource-rich countries. Incidence and mortality data were obtained from the National Cancer Registry Program Reports and the Cancer Incidence in 5 Continents publications. Further, a comprehensive review of medical literature was done for information on individual cancers as well as survival data. 1.6 to 4.8% of all cancer in India is seen in children below 15 years of age and the overall incidence of 38 to 124 per million children, per year, is lower than that in the developed world. The considerable inter-regional variation in incidence and mortality rates across India suggests a possible deficiency in ascertainment of cases and death notification, particularly in rural areas. The marked male preponderance of Hodgkin's disease, lower incidence of central nervous system tumors, and higher incidence of retinoblastoma merit further analysis.

Oral squamous cell carcinoma: etiology, pathogenesis and prognostic value of genomic alterations.

Abstract: Tumours of the head and neck comprise an important group of neoplasia, the incidence of which is increasing in many parts of the world. This increase remains high, despite all the advances in modern medicine. This malignancy is more prevalent in the developing world and unfortunately, has not received satisfactory attention as the more prevalent cancers of the developed world, like lung, breast, or colon cancer. Recent advances in diagnosis and therapeutic techniques of these lesions have yielded novel molecular targets, uncovered signal pathway dominance and advanced early cancer detection. This review covers recent advances in our understanding of the etiology, molecular changes and the possible role that genomic and proteomic research might play in the diagnosis and effective cure of this modern-day scourge.

Profile of breast cancer patients at a tertiary care hospital in north India.

Abstract: Background and Aims: We carried out this study in order to know the epidemiology and management strategies for breast cancer patients in our patient population. Settings and Design: The epidemiological data pertaining to demography and risk factors for carcinoma breast were analyzed retrospectively in patients admitted to a tertiary care hospital of North India. Materials and Methods: Hospital records of 304 patients admitted for over a period of five years (January 1998 to December 2002) were used for data analysis. Statistical Analysis Used: Paired T-test . Results: Mean age of our female breast cancer patients was found to be lower compared to the western world, with an average difference of one decade. A majority of the patients were from a rural background and had a longer duration of symptoms compared to urban patients. Lump in the breast was a dominant symptom. Familial breast cancer was uncommon. Left sided breast cancer was slightly preponderant. Screening by mammography and staging procedures such as bone scan, Computed Tomography (CT) scan, and Magnetic Resonance Imaging (MRI) were sparsely used. The most common histology was infiltrating duct carcinoma. Conclusion: Modified radical mastectomy was found to be a safe operative procedure. Breast conservative surgery, although considered the gold standard in early breast cancer, was found unsuitable for our patients, due to the social background and lack of intensive radiotherapy and chemotherapy backup. Infiltrating duct carcinoma was more commonly associated with positive lymph nodes compared to other histopathologies. Cases operated by surgical oncologists had better axillary clearance. Neoadjuvant chemotherapy was used mainly by surgical oncologists suggesting a more rational approach toward the management of breast carcinoma.