International Journal of Applied Biology and P
About: International Journal of Applied Biology and P is an academic journal. The journal publishes majorly in the area(s): Population & Phytochemical. Over the lifetime, 491 publications have been published receiving 2212 citations.
TL;DR: The results showed that B.subtilus is more susceptible to test spices as compared to E.coli, which showed that the cinnamon ethanolic extracts are equally effective against both Gram negative and Gram positive bacteria.
Abstract: Many of the spices used daily have been documented to be antimicrobial and have medicinal value as well. Most bacteria are sensitive to the extracts from plants such as clove, garlic, mustard, onion, oregano, turmeric etc. spices such as garlic turmeric and cinnamon has been used as antimicrobial agents in their raw form for the treatment of wounds and injuries and joint pains etc. The present study was conducted to investigate the antibacterial activity of garlic, cinnamon and turmeric. Different concentrations of extracts were prepared by using two solvents water and ethanol. The antibacterial activity was tested against Bacillus subtilus (DSM 3256) and E.coli (ATCC 25922) at different concentration of extracts of spices by using disc diffusion method. According to the results among the selected spices garlic had the best inhibitory activity showing maximum zone of 26mm against Bacillus subtilis DSM and a zone of 22mm against E.coli ATCC 25922. The aqueous extracts of garlic were more effective than ethanolic extract. In the case of cinnamon and turmeric, the ethanolic extracts were more effective exhibiting zones of 16mm against B.subtilis DSM 3256 and 17mm against E.coli , which showed that the cinnamon ethanolic extracts are equally effective against both Gram negative and Gram positive bacteria. The widest zones formed by ethanolic extract of turmeric against B.subtilis was measured as 14mm and it was 11mm for E.coli ATCC 25922. The results showed that B.subtilus is more susceptible to test spices as compared to E.coli.
TL;DR: The present investigation clearly reveals the larvaicidal potentials of selected actinobacterial isolates in the Muthupet mangrove soil and sediments and strategies for optimizing of large scale production of cellbiomass and larvicidal compounds are suggested as future course of action.
Abstract: Totally 30 actinobacteria isolates were screened for their larvicidal activity against Anopheles mosquito larvae. Of them four isolates producing strong larvicidal activity. These isolates were morphologically characterized and identified as the isolate CC17, SM13 as Streptomyces sp, isolate SH15 as Streptosporangium, isolate S22 as Micropolyspora. The present investigation clearly reveals the larvaicidal potentials of selected actinobacterial isolates in the Muthupet mangrove soil and sediments. To exploit these findings for humanwelfare, it is necessary to carryout field trial and strategies for optimizing of large scale production of cellbiomass and larvicidal compounds are suggested as future course of action.
TL;DR: In this article, chemical analysis of well and bore well water samples was carried out from eight sampling sites of Guntur rural area for the month of February 2010, and the results obtained on WQI from different sampling stations were found to be varied from 38.3. to 42.6.
Abstract: Physico - Chemical analysis of well and bore well water samples was carried out from eight sampling sites of Guntur rural area for the month of February 2010. The analysis of different parameters namely- pH, turbidity, colour, total alkalinity, total hardness, chloride, sulphate, nitrate, TDS, DO, BOD, COD were carried out as per standard methods . The present study aimed to calculate water quality index (WQI) in order to assess the suitability of water for drinking purposes. The results obtained on WQI from different sampling stations were found to be varied from 38.3. to 42.6.
TL;DR: In this paper, the authors studied the effect of the duration of the residence time of a dosage form at a particular site and controlled the release of drug from the dosage form in order to achieve controlled plasma level of the drug as well as improving bioavailability.
Abstract: Mucoadhesion had been a topic of interest in the design of drug delivery system to prolong the residence time of the dosage form with the under lying absorption surface to improve and enhance the bioavailability of drugs. Mucoadhesion occurs between two surfaces, one of which is a mucous membrane and another is drug delivery system. Pharmaceutical aspects of mucoadhesion had been the subject of great interest during recent years because mucoadhesion could be a solution for bioavailability problems that result from a too short length of stay of the pharmaceutical dosage form at the absorption site within the gastro-intestinal tract. It had been a great challenge to the pharmaceutical sciences in order to enhance localised drug delivery or to deliver ‘difficult’ molecules (proteins and oligonucleotides) into the systemic circulation. Mucoadhesive systems remain in close contact with the absorption tissue, the mucous membrane releasing the drug at the action site leading to increase in bioavailability (both local and systemic effects). Extending the residence time of a dosage form at a particular site and controlling the release of drug from the dosage form are useful especially for achieving controlled plasma level of the drug as well as improving bioavailability. The main objective of this study was to selectively collect the data which were extended the gastrointestinal residence time of the dosage form and controlled the release of mucoadhesives.
TL;DR: The chemical composition of essential oils obtained from Rosmarinus officinalis and Juniperus Phoenicea (family Cupressaceae) were determined and the major compound in aerial parts was α-pinene followed by α-phyllandrene.
Abstract: The chemical composition of essential oils obtained from Rosmarinus officinalis (family Lamiaceae) and Juniperus Phoenicea (family Cupressaceae) were determined. Their essential oil was determined by hydro-distillation, analysed by GC/MS and GC-FID. The analyses for leaves of Rosmarinus officinalis resulted in the identification of twenty three compounds, representing 63.81% of the total oil and the yields were 0.54%. The major component was α-pinene (18.25%); other predominant components were camphor (6.02%), 1.8-cineole (5.25%), camphene (5.02%), β-pinene (4.58%), bornylacetate (4.35%), limonene (3.56%), borneol (3.10%), α-terpineol (2.89%) and cymene (2.02%). Twenty tree compounds were identified in leaves oil of Juniperus phoenicea representing 81.87% of the total oil composition. The yield of essential oil was 1.62% and the major compound in aerial parts was α-pinene (49.15%) followed by α-phyllandrene (7.39%), mycene (5.24%), β-pinene (3.58%), linalool (2.54%), piperitone (1.56%), γ-terpinene (1.28%), Trans-pinocarveole (1.23%) ρ-cymene (1.10%), α terpineol (1.02%) and γ-cardinene (1.01%).
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