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JournalISSN: 0141-8130

International Journal of Biological Macromolecules

About: International Journal of Biological Macromolecules is an academic journal. The journal publishes majorly in the area(s): Starch & Adsorption. It has an ISSN identifier of 0141-8130. Over the lifetime, 19764 publication(s) have been published receiving 431431 citation(s). The journal is also known as: Int J Biol Macromol. more

Topics: Starch, Adsorption, Chitosan more

Open accessJournal ArticleDOI: 10.1016/S0141-8130(98)00040-3
Abstract: The emphasis of this review is on starch structure and its biosynthesis. Improvements in understanding have been brought about during the last decade through the development of new physicochemical and biological techniques, leading to real scientific progress. All this literature needs to be kept inside the general literature about biopolymers, despite some confusing results or discrepancies arising from the biological variability of starch. However, a coherent picture of starch over all the different structural levels can be presented, in order to obtain some generalizations about its structure. In this review we will focus first on our present understanding of the structures of amylose and amylopectin and their organization within the granule, and we will then give insights on the biosynthetic mechanisms explaining the biogenesis of starch in plants. more

Topics: Amylopectin (52%)

1,681 Citations

Journal ArticleDOI: 10.1016/S0141-8130(05)80008-X
J.-F. Revol, H. Bradford1, Julie Giasson1, Robert H. Marchessault1  +1 moreInstitutions (1)
Abstract: In many skeletal support systems of plants and animals, cellulose, chitin, and collagen occur in the form of microfibrils ordered in a chiral nematic fashion (helicoids). However, these structures remain poorly understood due to the many constituents present in biological tissues. Here we report an in vitro system that attracts by its simplicity. Only one chemical component, cellulose, is present in the form of fibrillar fragments dispersed in water. Above a critical concentration the colloidal dispersion separates spontaneously into a chiral nematic liquid crystalline phase. On drying this phase solidifies into regularly twisted fibrillar layers that mimic the structural organization of helicoids in nature. more

Topics: Microfibril (55%)

916 Citations

Open accessJournal ArticleDOI: 10.1016/J.IJBIOMAC.2008.09.007
Natália M. Alves1, João F. Mano1Institutions (1)
Abstract: Chitosan is a natural based polymer, obtained by alkaline deacetylation of chitin, which presents excellent biological properties such as biodegradability and immunological, antibacterial and wound-healing activity. Recently, there has been a growing interest in the chemical modification of chitosan in order to improve its solubility and widen its applications. The main chemical modifications of chitosan that have been proposed in the literature are reviewed in this paper. Moreover, these chemical modifications lead to a wide range of derivatives with a broad range of applications. Recent and relevant examples of the distinct applications, with particular emphasis on tissue engineering, drug delivery and environmental applications, are presented. more

632 Citations

Journal ArticleDOI: 10.1016/J.IJBIOMAC.2007.10.003
Abstract: Fucoidan, a group of sulfated heteropolysaccharide, was extracted from Laminaria japonica, an important economic alga species in China. Three sulfated polysaccharide fractions (F1, F2, and F3) were successfully isolated through anion-exchange column chromatography and had their antioxidant activities investigated employing various established in vitro systems, including superoxide and hydroxyl radical scavenging activity, chelating ability, and reducing power. Chemical analysis suggested that F1 and F3 were heteropolysaccharide in which galactose was the major component, while F2 was a typical fucoidan. All fractions possessed considerable antioxidant activity, and F1, F2 and F3 had stronger antioxidant ability than fucoidan in certain tests. The correlation between the sulfate content and scavenging superoxide radical ability was positive. Available data obtained with in vitro models suggested that the ratio of sulfate content/fucose was an effective indicator to antioxidant activity of the samples. more

Topics: Fucoidan (61%), Fucose (54%)

575 Citations

Journal ArticleDOI: 10.1016/J.IJBIOMAC.2013.04.043
Abstract: This manuscript briefly reviews the extensive research as well as new developments on chitosan based nanomaterials for various applications. Chitosan is a biocompatible and biodegradable polymer having immense structural possibilities for chemical and mechanical modification to generate novel properties and functions in different fields especially in the biomedical field. Over the last era, research in functional biomaterials such as chitosan has led to the development of new drug delivery system and superior regenerative medicine, currently one of the most quickly growing fields in the area of health science. Chitosan is known as a biomaterial due to its biocompatibility, biodegradability, and non-toxic properties. These properties clearly point out that chitosan has greater potential for future development in different fields of science namely drug delivery, gene delivery, cell imaging, sensors and also in the treatment as well as diagnosis of some diseases like cancer. Chitosan based nanomaterials have superior physical and chemical properties such as high surface area, porosity, tensile strength, conductivity, photo-luminescent as well as increased mechanical properties as comparison to pure chitosan. This review highlights the recent research on different aspect of chitosan based nanomaterials, including their preparation and application. more

559 Citations

No. of papers from the Journal in previous years

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Journal's top 5 most impactful authors

John F. Kennedy

60 papers, 1K citations

Rizwan Hasan Khan

51 papers, 1.1K citations

Ali Akbar Saboury

37 papers, 839 citations

Ali Akbar Moosavi-Movahedi

29 papers, 602 citations

Khalid Mahmood Zia

28 papers, 1.8K citations

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