International journal of current research and review 

About: International journal of current research and review is an academic journal published by Radiance Research Academy. The journal publishes majorly in the area(s): Medicine & Population. It has an ISSN identifier of 0975-5241. It is also open access. Over the lifetime, 2874 publications have been published receiving 5681 citations.

Phytochemical and pharmacological studies on ocimum basilicum linn - a review -

Abstract: Plants are one of the most important sources of medicines. Basil (Ocimum basilicum Linn.) is one such plant which symbolizes all that is wondrous in nature because, the whole plant has been used as traditional medicine for household remedy against various human ailments from antiquity. The objective of this paper is to review the literature regarding Ocimum basilicum, specifically for its chemical properties, therapeutic benefits and scientific studies. This review consists of all publications relevant to Ocimum basilicum that were identified by the authors through a systemic search of major computerized medical database. Studies indicate Ocimum basilicum to possess analgesic, anti inflammatory, antimicrobial, antioxidant, anti ulcerogenic, cardiac stimulant, chemomodulatory, CNS depressant, hepatoprotective, hypoglycemic, hypolipidemic, immunomodulator and larvicidal activities. The drug was also searched for its folkloric claims. It is used in traditional medicine as a tonic and vermifuge, and Basil tea taken hot is good for treating nausea, flatulence, and dysentery. The oil of the plant has been found to be beneficial for the alleviation of mental fatigue, cold, spasm, rhinitis, and as a first aid treatment for wasp stings and snakebites. Preliminary studies have found various constituents of Ocimum basilicum to exhibit a variety of therapeutic effects. These results are very encouraging and indicate that this drug should be studied more extensively to confirm these results and to find other potential therapeutic effects.

Bioremediation of textile dye using white rot fungi: a review

Abstract: Industrial development worldwide has led to an increase in the amount of wastewater production leading to a considerable decrease in levels and quality of the natural water in the ecosystem Textile dyes are an important class of pollutants in natural water ecosystem Textile dyes are molecules designed to impart a permanent colour to textile fabrics Effluent from textile dyeing units contain large amount of dyes and create an environmental problem, which increase toxicity and decrease the aesthetic value of rivers and lakes A variety of physio-chemical methods are in use worldwide However, there is an increasing concern as to their impact in effectively treating textile effluents as they introduce secondary pollutants during the ‘remediation’ process which are quite costly to run and maintain Research on biological treatment has offered simple and cost effective ways of bioremediation textile effluents This review summarizes the efficiency of white rot fungi and their enzymes for the treatment and removal of textile dye containing effluents The advantages and disadvantages of the various methods are discussed and their efficacies are compared

Depression among geriatrics:prevalence and associated factors

Abstract: Method: 182 participants aged over 60 from an urban area, Ashapur, Raichur were interviewed to assess their psychiatric morbidity and associated factors using geriatric depression scale. Objective: To establish prevalence of depression and associated factors in geriatrics in Ashapur urban area, Raichur Dist, Karnataka., India. Type of study: Cross sectional. Methodology: The cross sectional epidemiological study was conducted in urban slums of Ashapur, Raichur Dist. The study area has a population of 25486 with a geriatric population of 2536.A sample size of 182 was estimated using Random Sampling Technique. Study group: 182 Study area: Ashapur urban area, Raichur Dist, Karnataka. Study period: July17 to October 17. Study tool: Pretested Questionnaire. Analysis: Descriptive statistics and other appropriate statistical studies will be used. Results: This study revealed that 32.4% of individuals were suffering from depression. We conclude that depression in elderly is associated with poor socio economic status, unemployment, disrupted marital status, illiteracy, and substance abuse. Conclusion: By the end of the study we concluded that prevalence of depression in geriatrics is significantly high. It is mainly associated with substance abuse, unemployment, disrupted mental status, illiteracy and poor economic status.

Siderophore production by the isolates of fluorescent pseudomonads

Abstract: Production of secondary metabolites including siderophores is yet another mechanism by which fluorescent pseudomonads acts as a biocontrol agent. Siderophores are secreted under iron limitation and have a very high affinity for ferric iron. The resulting ferric-siderophore complex is unavailable to other organisms, but the producing strain can utilize this complex via a specific receptor in its outer cell membrane. In this way, siderophore producing fluorescent Pseudomonads may restrict the growth of phytopathogens. In the present study the siderophore production by the isolated strains of fluorescent pseudomonads has been reviewed. Of the 22 isolates which showed the abilty to produce siderophores, 6 isolates were shown to produce catecholate type of siderophores and the remaining 16 isolates showed the presence of hydroxamate

Nisin: production and mechanism of antimicrobial action

Abstract: Nisin is a heat stable lantibiotic consisting of 34 amino acids. Of these amino acids, there are several unusual amino acids including dehydroalanine, dehydrobutyrine, aminobutyric acid, lanthionine and β-methyllanthionine. It has antimicrobial activity against many species of Gram positive bacteria, but not Gram negative bacteria due to their outer membrane barriers. However, when used in combination with other chemical or physical treatments that destabilize the outer membranes, nisin can inhibit Gram negative bacteria. Nisin has been used as a food preservative in many food industries because it is legally approved as safe for use in food and beverage. The knowledge on the production and mechanism of antimicrobial action of nisin is important for the understanding how nisin contains unusual amino acids and how it kills sensitive bacteria. The knowledge may also be a factor for the successful application of nisin. Therefore, this review focuses on presenting these two aspects of nisin.