International Journal of Green Pharmacy 

About: International Journal of Green Pharmacy is an academic journal published by Medknow. The journal publishes majorly in the area(s): Phytochemical & Antimicrobial. It has an ISSN identifier of 0973-8258. It is also open access. Over the lifetime, 981 publications have been published receiving 8612 citations. The journal is also known as: IJGP.

Ageratum conyzoides L.: A review on its phytochemical and pharmacological profile

Abstract: Ageratum conyzoides L. (AC) is an annual herbaceous plant with a long history of traditional medicinal uses in many countries in the world, especially in the tropical and subtropical regions. Th e weed has been known since ancient times for its curative properties and has been utilized for treatment of various ailments, such as burns and wounds, for antimicrobial properties, for many infectious conditions and bacterial infections, arthrosis, headaches and dyspnea, pneumonia, analgesic, anti-infl ammatory, antiasthmatic, antispasmodic and haemostatic eff ects, stomach ailments, gynaecological diseases, leprosy and other skin diseases. A wide range of chemical compounds including alkaloids, cumarins, fl avonoids, chromenes, benzofurans, sterols and terpenoids have been isolated from this species. Extracts and metabolites from this plant have been found to possess pharmacological and insecticidal activities. Th is contribution provides a comprehensive review of its ethnomedical uses, chemical constituents and the pharmacological profi le as a medicinal plant. Particular attention has been given to analgesic and anti-infl ammatory, antibacterial and wound healing properties, radioprotective, antifungal, anthelmintic and nematicidal, insecticidal eff ects presented in this review such that the potential use of this plant either in pharmaceutics or as an agricultural resource can be evaluated. Key words: Ageratum conyzoides, alkaloids, benzofurans, bioactivity, chromenes, fl avonoids, terpenoids

Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica. L

Abstract: Preliminary phytochemical and antibacterial investigations were carried out of the crude extracts obtained from the leaf of Adhatoda vasica, using solvents of varied polarity. The presence of phenols, tannins, alkaloids, anthraquinones, saponins, flavanoids, aminoacids and reducing sugars was indicated by the tests conducted. The effect of ethanol, petroleum ether and water extracts were tested on Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Pseudomonas aeroginosa, Proteus vulgaris, Klesiella pneumoniae and Candida albicans. The minimum inhibitory concentration of the crude extracts was determined for various organisms. Key words: Adhatoda vasica, antibacterial activity, minimum inhibitory concentration

A review on Bacopa monniera: Current research and future prospects

Abstract: In recent times, the use of herbal products has increased tremendously in the western world as well as in developed countries. Lately, one of the outstandingly important medicinal plants, widely used therapeutically in the orient and becoming increasingly popular in the west is Bacopa monniera, a well-known nootropic. The present review summarizes our current knowledge of pharmacological actions, preclinical and clinical studies, major bioactives, reported mechanisms of actions, clinical efficacy, safety and the possibility of interactions of the herb with the conventional drugs. Simultaneously, research updates as well as avenues for further research are also mentioned concerning the plant. Key words: Bacopa monniera, neurotonics, clinical studies, herb-drug interactions, preclinical studies

Anti-diabetic activity of leaf extract of Tridax procumbens

Abstract: A study of ancient literature indicates that diabetes was fairly well known and well conceived as an entity in India. Plant-based drugs have been used against various diseases since a long time. Th e nature has provided abundant plant wealth for all the living creatures, which possess medicinal virtues. Th e essential values of some plants have long been published, but a large number of them have remained unexplored to date. Th erefore, there is a necessity to explore their uses and to conduct pharmacognostic and pharmacological studies to ascertain their therapeutic properties. In fact, nowadays, diabetes is a global problem. Hence, the present study aims to open new avenues for the improvement of medicinal uses of Tridax procumbens (Compositae) for the selected area for diabetes. Another important objective of such a study is to bring the anti-diabetic medicinal plants sector on a fi rm scientifi c footing, raise awareness and add value to the resource. Dried aqueous, alcoholic, and petroleum ether (60-80°C) extracts of leaves of Tridax procumbens were subjected for hypoglycaemic activity in Wistar rats (150-200 g). Blood sugar level was determined using digital glucometer. Th e oral administration of leaf extracts at doses of 200 mg kg−1 lead to a signifi cant blood glucose reduction. Th is laid the foundation to study the active compounds of such anti-diabetic plants that are responsible for the hypoglycemic activities. It also proves the traditional claim of Mandesh region with regard to Tridax procumbens for its anti-diabetic activity. Key words: Alloxan-induced diabetes, hypoglycaemic activity, Tridax procumbens

Antibacterial activity of plants used in Indian herbal medicine

Abstract: Delonix elata, Enicostemma axillare, Merremia tridentata, Mollugo cerviana and Solanum incanum are medicinal plants used in traditional Indian medicine for the treatment of various ailments. These plants were selected to evaluate their potential antibacterial activity. To determine antibacterial activity and phytochemicals in the crude extracts of five medicinal plants used in traditional Indian medicine for the treatment of various ailments like rheumatism, piles fever, skin diseases and snake bite. The antibacterial activity of organic solvent extracts of these plants were determined by disc diffusion and broth dilution techniques against grampositive bacterial strains (Bacillus subtilis, Staphylococcus aureus) and gram-negative bacterial strains (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa). Results revealed that the chloroform and methanol extracts of D. elata and methanol extracts of M. cerviana exhibited significant antibacterial activity against gram-positive and gram-negative strains with minimum bactericidal concentration (MBC) ranging from 1.5 to 100 mg/ml. Methanol extracts of M. tridentata exhibited activity only against gram-positive bacterial strains with MBC ranging from 12.5 to 100 mg/ml. Extracts of E. axillare and S. incanum showed activity only against B. subtilis and were not bactericidal at 100 mg/ml. The most susceptible organism to the organic extracts from all the studied plants was B. subtilis and the most resistant organism was P. aeruginosa. The presence of phytochemicals such as alkaloids, tannins, triterpenoids, steroids and glycosides in the extracts of these plants supports their traditional uses as medicinal plants for the treatment of various ailments. The present study reveals potential use of these plants for developing new antibacterial compounds against pathogenic microorganisms. Key words: Antibacterial, Enicostemma axillare, Merremia tridentata, Mollugo cerviana, Solanum incanum