Journal•ISSN: 0020-9996
Investigative Radiology
Lippincott Williams & Wilkins
About: Investigative Radiology is an academic journal published by Lippincott Williams & Wilkins. The journal publishes majorly in the area(s): Magnetic resonance imaging & Medicine. It has an ISSN identifier of 0020-9996. Over the lifetime, 7297 publications have been published receiving 203078 citations.
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TL;DR: This article develops ROC concepts in an intuitive way by identifying the fundamental issues that motivate ROC analysis and practical techniques for ROC data collection and data analysis.
Abstract: If the performance of a diagnostic imaging system is to be evaluated objectively and meaningfully, one must compare radiologists' image-based diagnoses with actual states of disease and health in a way that distinguishes between the inherent diagnostic capacity of the radiologists' interpretations of the images, and any tendencies to "under-read" or "over-read". ROC methodology provides the only known basis for distinguishing between these two aspects of diagnostic performance. After identifying the fundamental issues that motivate ROC analysis, this article develops ROC concepts in an intuitive way. The requirements of a valid ROC study and practical techniques for ROC data collection and data analysis are sketched briefly. A survey of the radiologic literature indicates the broad variety of evaluation studies in which ROC analysis has been employed.
1,780 citations
TL;DR: Awareness of the field strength and solvent associated with relaxivity data is crucial for the comparison and evaluation of relaxivity values and should be replaced by relaxivities measured at 1.5 T and at 3 T in plasma at physiological temperature.
Abstract: Rationale and Objectives:To characterize and compare commercially available contrast media (CM) for magnetic resonance imaging (MRI) in terms of their relaxivity at magnetic field strengths ranging from 0.47 T to 4.7 T at physiological temperatures in water and in plasma. Relaxivities also were quan
1,464 citations
1,314 citations
TL;DR: The echo pattern of the aortic root is elicited by locating the typical echo of the mitral valve and then angulating the transducer medially and sometimes cephalically.
Abstract: The echo pattern of the aortic root is elicited by locating the typical echo of the mitral valve and then angulating the transducer medially and sometimes cephalically. The characteristic echo pattern of the aortic root consists of paired undulating signals three to five cm apart. These signals move
908 citations
TL;DR: The purposes of this paper are to make users of ROC methodology in medical imaging aware of potential problems that should be confronted before an ROC study is begun and to indicate, at least broadly, how those problems may be dealt with, given the present state of the art.
Abstract: Receiver operating characteristic (ROC) analysis has been used in a broad variety of medical imaging studies during the past 15 years, and its advantages over more traditional measures of diagnostic performance are now clearly established. But despite the essential simplicity of the approach, worker
903 citations