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JournalISSN: 2319-7676

IOSR Journal of Pharmacy and Biological Sciences 

International organization of Scientific Research (IOSR)
About: IOSR Journal of Pharmacy and Biological Sciences is an academic journal. The journal publishes majorly in the area(s): Population & Antimicrobial. Over the lifetime, 1280 publications have been published receiving 4182 citations.

Papers published on a yearly basis

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Journal ArticleDOI
TL;DR: Ginger has a long history of medicinal use for more than 2000 years as one of the most versatile medicinal plants having a wide spectrum of biological activity.
Abstract: Ginger (Zingiber officinale) belong to Zingiberacae family is one of the famous spices all over the world. It is a perennial creeping plant with long leaves, yellow green flowers and thick tuberous rhizome. This is a type of storage root having pungent taste. Ginger has a long history of medicinal use for more than 2000 years as one of the most versatile medicinal plants having a wide spectrum of biological activity. From ancient times ginger has been exploited both as Ayurvedic and Chinese medicine for curing heart problems, menstruation disorder, food poisoning, osteoarthritis, epilepsy, nausea, inflammation, cough and cold, motion sickness, menstrual cramps, cancer and many more. Besides these it also exhibits antimicrobial and antioxidant properties. The medicinal properties of ginger are due to the presence of gingerol and paradol, shogaols, etc. Medicinal value of ginger and its knowledge provide the good platform for researchers for future research to protect human beings from several types of diseases.

82 citations

Journal ArticleDOI
TL;DR: Phosphorus fertilizer significantly enhanced growth and yield characters of the cowpea varieties used; plant height, leaf area, number of leaves and number of branches in all the weeks of measurement were significantly improved.
Abstract: Phosphorus is important for cowpea production in many tropical African soils with inherent low phosphorus fertility. Most farmers in Africa, however, do not have access to phosphorus fertilizer. Selection of cowpea lines that produce good yield under low soil phosphorus or those with high phosphorus use efficiency can be a low input approach to solving this problem. This research work was conducted in pot trials at the teaching and research farm of Michael Okpara University of Agriculture, Umudike, in the south eastern part of Nigeria to determine the effect of different phosphorus levels on growth and yield of three varieties of cowpea (Vigna unguiculata (L.) Walp), obtained from the germplasm unit of International Institute of Tropical Agriculture, Ibadan. The experiment consists of five phosphorus levels (0kgha, 20kgha, 40kgha, 60kgha and 80kgha) each of which contains seven replicates. Phosphorus fertilizer significantly enhanced growth and yield characters of the cowpea varieties used; plant height, leaf area, number of leaves and number of branches in all the weeks of measurement were significantly improved. Phosphorus also had a significant effect (p> 0.05) on seed yield per treatment, weight of 50 seeds, number of nodules, weight of nodules and total aboveground dry matter in all varieties used. However, variations were observed in the responses of the different cowpea varieties to phosphorus application. High yield values were observed in variety three; IT99K-573-2-1, followed by variety two; IT99K-573-1-1 and variety one; IT97K-499-35. Highest value in all the yield characters measured was observed in variety three: IT99K-573-2-1 at phosphorus fertilizer rate of 40kgha. When phosphorus is available, IT99K-573-2-1and 40kgha phosphorus application rate is recommended.

67 citations

Journal ArticleDOI
TL;DR: In this paper, the phytochemical constituents of aqueous and ethanolic leaf extracts of Moringa oleifera Lam were assessed and compared and the results proved the extensive use of the leaves of this plant in ethnomedicine and its potentials in drug formulation.
Abstract: The phytochemical constituents aqueous and ethanolic leaf extracts of Moringa oleifera Lam. were assessed and compared. The mineral and proximate analyses were done on the whole leaf extract. The result of the qualitative phytochemical constituents of both leaf extracts of Moringa oleifera showed presence of all the tested phytochemicals (flavonoids, anthraquinone, alkaloids, saponins, steroids, terpenoids, cardiac glycosides, anthocyanin, tannins and carotenoids) with water extracting more of the phytochemicals. Results showed the presence of iron (0.03g/100g), calcium (2.09g/100g), magnesium (0.48g/100g), potassium (1.62g/100g), phosphorus (0.04g/100g), zinc (0.005g/100g), copper (0.01g/100g) and sulphur (0.85g/100g). Proximate analysis revealed the presence of carbohydrate (57.01%), protein (18.92%), fats (2.74%), fibre (9.31%), moisture (4.09%) and ash (7.95%). The results from this study prove the extensive use of the leaves of this plant in ethnomedicine and its potentials in drug formulation.

55 citations

Journal ArticleDOI
TL;DR: In this article, a new and simple precipitation process using calcium hydroxide, phosphoric acid as phosphorus (P) and calcium (Ca) precursors and NaOH was used to synthesize a single phase HAP, with an average grain size of about 19 nm and surface area of 61 m 2 /g.
Abstract: hydroxyapatite (HAP, Ca10(PO4)6(OH)2) nanoparticles are important biocompatible materials and were successfully synthesized by a new and simple precipitation process using calcium hydroxide, phosphoric acid as phosphorus (P) and calcium (Ca) precursors and sodium hydroxide (NaOH). The crystal structures and morphologies of the as synthesized hydroxyapatite were analyzed by X-ray diffractions (X-ray), Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), energy dispersive x-ray spectroscopy (EDS) and transmission electron microscopy (TEM). Single phase HAP, with an average grain size of about 19 nm and surface area of 61 m 2 /g, was obtained. Additionally, the antibacterial activity of the as synthesized HAP nanoparticles related to gram positive and gram negative bacteria's were examined, too. Finally, the obtained results indicated that the HAP nanoparticles possess excellent and a broad spectrum antibacterial activity and it can potentially be applied in medical and environmental fields.

55 citations

Journal ArticleDOI
TL;DR: It was revealed that the aqueous as well as the methanolic extract of seeds were effective to inhibit the bacterial pathogens while in case of chloroform extract of Carica papaya leaves did not show any inhibition against the bacteria and the aQueous leaf extract was potent to inhibit them.
Abstract: The study dealt with the antibacterial activity of aqueous, chloroform extract of leaves and aqueous, methanolic extract of seeds of Carica papaya var. pusa dwarf through agar well diffusion assay against Staphylococcus aureus, Pseudomonas aeruginosa, E. coli and Salmonella typhi. It was revealed that the aqueous as well as the methanolic extract of seeds were effective to inhibit the bacterial pathogens while in case of chloroform extract of Carica papaya leaves did not show any inhibition against the bacteria and the aqueous leaf extract was potent to inhibit them.

54 citations

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Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
2017225
201693
20152
2014473
2013298
2012189