Showing papers in "Journal of Asian Natural Products Research in 2007"

TL;DR: The research results indicated that after two weeks of chronic administration, PIP and AES at doses of 10–20 mg/kg significantly reduced the duration of immobility in both FST and TST, without accompanying changes in locomotor activity in the open-field test.

TL;DR: A new isoflavone, corylinin, along with six known compounds, isopsoralen, psoralen (3), sophoracoumestan A, neobavais oflavone (5), daidzin (6) and uracil (7), have been isolated from the dried fruits of Psoralea corylifolia L.

TL;DR: The data showed that THSG possessed an anti-inflammatory effect, which was perhaps related to the inhibition of COX-2 enzyme activity and expression in RAW264.7 macrophage cells.

TL;DR: All eight compounds (1–8) were found to show the DPPH free radical scavenging activity with EC50 from 8.8 to 55.9 μM.

TL;DR: THSG possesses the antagonistic effects on oxidation of lipoprotein, proliferation and decrease of NO content of CASMCs, which partially explain the mechanism of anti-atherosclerosis of Polygonum multiflorum Thunb.

TL;DR: Three new compounds have been isolated from the aerial part of Centella asiatica through spectral studies including 2D NMR experiments (HMQC, HMBC, 1H–1H COSY, NOESY and J resolved).

TL;DR: Bioassay guided fractionation of Boenninghausenia sessilicarpa resulted in the isolation of a new dimeric coumarin glucoside 9′-methoxyl rutarensin and a cytotoxic compound rutamarin, as well as an antivirus component leptodactylone, together with six known coumarins.

TL;DR: A new lupane acid, 2β-carboxyl,3β-hydroxyl-norlupA (1)-20 (29)-en-28-oic acid (1), together with five known l upane acid derivatives (2–6), were isolated from the stings of Gleditsia sinensis Lam and their structures were elucidated on the basis of 1D and 2D NMR techniques.

TL;DR: Two new diterpenes isolated from the methanol extract of the brown alga Dictyota sp.

TL;DR: Results indicated that theacrine possessed potent sedative and hypnotic properties and its central nervous system effects were different from those of caffeine and theobromine.

TL;DR: Two new phenolic compounds, gastrodin A and gastrol A, together with 7 known ones, have been isolated from the EtOH extract of the rhizomes of Gastrodia elata Blume (Orchidaceae), and their structures were elucidated by spectroscopic analysis and comparison of their spectral data with those reported previously.

TL;DR: Six new sesquiterpenes have been isolated from the red alga Laurencia tristicha and tested for cytotoxic activities against several human cancer cell lines including lung adenocarcinoma, stomach cancer, hepatoma, liver cancer, colon cancer, and HeLa cell lines.

TL;DR: Results showed that cardiomyocyte apoptosis and expression of various apoptosis associated genes are inhibited after treatment with astragaloside, suggesting that the anti-apoptotic activity of astraggaloside may contribute to the improvement of clinical outcomes in treating myocarditis with pharmaceutics of Astragalus membranaceus.

TL;DR: A novel analgesic pyrazine derivative, named crotonine, was isolated from the leaves of Croton tiglium L and inhibited remarkably the acetic acid-induced writhing in mice.

TL;DR: Two new triterpene glycosides, hillasides A and B, were isolated from the sea cucumber H. hilla Lesson together with one known glycoside holothuria B, and showed significant cytotoxicity against eight human tumour cell lines.

TL;DR: The results showed that these compounds demonstrated potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.

TL;DR: The chemical constituents research of the fermentation of Penicillium thomi separated from the root of Bruguiera gymnorrhiza led to the isolation of a new compound, 4′,5-dihydroxy-2,3-dimethoxy-4-(hydroxypropyl)-biphenyl (1) and 11 known compounds.

TL;DR: Three new lignans were isolated from the 60% ethanol extract of stems of Sambucus williamsii Hance by chromatographic methods and their structures were established by spectral analysis.

TL;DR: Silymarin protected A375-S2 cell against UV-induced apoptosis was partially through SIRT1 pathway and modulation of the cell cycle distribution, possibly providing a prolonged time for efficient DNA repair.

TL;DR: Three new bibenzyls, stilbostemins M–O, and a new tocopherol, 6-methoxy-3,4-dehydro-δ-tocopherol were revealed together with four known compounds, which exhibited strong antibacterial activities against Staphylococcus aureus and S. epidermidis.

TL;DR: A lignan and two aromatic compounds were isolated from the branches of the mangrove plant, Bruguiera gymnorrhiza, and among them, 1 and 2 were new compounds; 3 was isolated from a natural source for the first time.

TL;DR: Isolation and structure elucidation of two new compounds, kakispyrone and kakisaponin A, together with 11 known compounds, from the leaves of Diospyros kaki L. are described.

TL;DR: Two new flavonoids were isolated from the 95% ethanolic extract of the dried roots of Lespedeza cuneata together with betulinic acid, β-sitosterol, hexacosanoic acid 2,3-dihydroxy-propyl ester and their structures were elucidated by spectral analysis.

TL;DR: Two new lanostane triterpenoids, 3-epipachymic acid and 3-oxo-5α-lanosta-8,24-dien-21-oic acid, together with a known compound, were isolated from the fruiting body of Ganoderma resinaceum and showed significant cytotoxic activity.

TL;DR: A new phenyl glycoside, scrophenoside D, and a new phenylethyl gly coside are isolated from the stems of Picrorhiza scrophulariiflora and their structures are elucidated by spectroscopic and chemical methods.

TL;DR: Two new compounds, alternanthin B and N-trans-feruloyl-3,5-dimethoxytyramine, along with four known compounds were isolated from the aerial parts of Alternanthera philoxeroides and their structures were elucidated on the basis of spectroscopic methods.

TL;DR: The results suggested that silymarin could also exaggerate the apoptotic effect of anti-Fas agonistic antibody CH11 on A375-S2 cells.

TL;DR: A new eudesmane-type sesquiterpenoid, hedytriol, was isolated from Hedychium yunnanense (Zingiberaceae) and the structure of 1 was determined as ( − )-7aH-eudes mane-1β, 4α, 11-triol.

TL;DR: Five norisoprenoids were isolated from the green marine alga Ulva lactuca and two new compounds were assigned to (3R,5R,6R,7E)3,5,6-trihydroxy-7-megastigmen-9-one.

TL;DR: Phytochemical investigation of the fruits of Cucurbita pepo cv dayangua has led to the isolation of two cucurbitane glycosides, and compound 4 is a new one.