Journal•ISSN: 0883-9115
Journal of Bioactive and Compatible Polymers
SAGE Publishing
About: Journal of Bioactive and Compatible Polymers is an academic journal published by SAGE Publishing. The journal publishes majorly in the area(s): Self-healing hydrogels & Chitosan. It has an ISSN identifier of 0883-9115. Over the lifetime, 1217 publications have been published receiving 24038 citations.
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TL;DR: In this paper, the authors define the weight equilibrium swelling ratio, q, which is defined as the weight of the swollen polymers, as a function of the external environment conditions.
Abstract: or by semipermanent physical crosslinks such as entanglements. They may be neutral, anionic, cationic or ampholytic in nature. Because of their nature, they show swelling behavior dependent on the external environment conditions. Polymer complexes can be broken or polymer networks can be swollen by changing the external environment. This process results in the drastic change in their swelling ratio. Parameters defining their swelling behavior are the weight equilibrium swelling ratio, q, which is defined [1] as the weight of the swollen
729 citations
TL;DR: The physicochemical properties of chitosan, as well as its numerous applications, are reviewed with particular emphasis on its use in water treat ment, pharmaceutics, agriculture and membrane formation as discussed by the authors.
Abstract: Chitosan, a polycationic polymer and waste product from the sea food processing industry, is an abundant natural resource that has, as yet, not been fully utilized. Advantages of this polymer include availability, low cost, high biocompatibility, biodegradability and ease of chemical modification. In this paper, the physicochemical properties of chitosan, as well as its numerous applications, are reviewed with particular emphasis on its use in water treat ment, pharmaceutics, agriculture and membrane formation.
662 citations
TL;DR: This new elastomeric polypeptide biomaterial which is based on the most striking repeating sequence in the mammalian elastic fiber exhibits an extraordinary biocompatibility.
Abstract: The complete series of the recommended generic biological tests for materials and devices in contact with tissues and tissue fluids and blood have been carried out by an independent testing laborat...
257 citations
TL;DR: The feasibility of collagen type II electrospinning has been demonstrated and the novel scaffolds produced are composed of nano- to micron-scale fiber diameters that have been shown to be compatible with chondrocytes.
Abstract: Collagen is the natural scaffolding found in all tissues and has been explored extensively for use as a tissue engineering scaffold with limited success. In this feasibility study, the electrospinning of collagen type II and subsequent chondrocyte seeding was investigated for potential use in cartilage tissue engineering. The electrospinning process utilized lyophilized, chicken sternal cartilage collagen type II suspended in 1,1,1,3,3,3 hexaflouro-2-propanol and demonstrated that collagen type II could be electrospun to form nonwoven fibrous mats composed of type II fibers that ranged from 110 nm to 1.8μm in diameter. The fiber diameter was dependant on the type II concentration in solution with a higher concentration producing the larger diameters. The preliminary chondrocyte seeding study demonstrated that electrospun collagen type II scaffolds support cell growth and are readily infiltrated. In conclusion, the feasibility of collagen type II electrospinning has been demonstrated and the novel scaffold...
203 citations
TL;DR: To monitor the fate of alginate following systemic administration, a method was developed that allowed the covalent incorporation of approximately 1 mol% tyrosinamide, which was subsequently stable on storage at 4°C for 30 days, with very little free [125I] iodide released over that period.
Abstract: Tb monitor the fate of alginate following systemic administration, a method was developed that allowed the covalent incorporation of approximately 1 mol% tyrosinamide. The product could be radioiodinated to a high specific activity, and was subsequently stable on storage at 4°C for 30 days, with very little (c 1%) free [125I] iodide released over that period. Twenty-four hours following intravenous administration, the low molecular weight fraction (<48,000) of the injected polymer was excreted in the urine while the larger polymer fraction remained in the circulation and did not readily accumulate in any of the tissues. Almost all of the dose administered by intraperitoneal injection was transferred from the peritoneal cavity to the blood compartment within 24 h, with the low molecular weight fraction of the polymer excreted in the urine. Following subcutaneous administration, the majority (-70%) of the injected dose was retained at the site of injection at 24 h.
164 citations