Showing papers in "Journal of Biomedical Informatics in 2010"

TL;DR: Findings show that TAM predicts a substantial portion of the use or acceptance of health IT, but that the theory may benefit from several additions and modifications.

TL;DR: How the biomedical informatics (BMI) community, especially consortia that share data and applications, can take advantage of a new resource called "cloud computing" is examined.

TL;DR: Experimental results demonstrate that the proposed approach is able to select feature subsets with better classification performance than the SFFS method and the integrated feature pre-selection mechanism helps to solve the over-fitting problems and reduces the chances of getting a local optimal solution.

TL;DR: This work surveys the literature and considers three aspects of eligibility criteria knowledge representation to be essential constructs of a formal knowledge representation for eligibility criteria, which should inform the development and choice of the constructs toward cost-effective knowledge representation efforts.

TL;DR: Association rule mining appears to be a useful tool for identifying clinically accurate associations between medications, laboratory results and problems and has several important advantages over alternative knowledge-based approaches.

TL;DR: The authors evaluate the ability of Random Indexing (RI), a scalable distributional model of word associations, to draw meaningful implicit relationships between terms in general and biomedical language, and demonstrate that the original implementation of RI is ineffective at inferring meaningful indirect connections.

TL;DR: An ontology of PGx relationships built starting from a lexicon of key pharmacogenomic entities and a syntactic parse of more than 87 million sentences from 17 million MEDLINE abstracts is described, creating a network of 40,000 relationships between more than 200 entity types with clear semantics.

TL;DR: A comparative introduction to TCM and modern biomedicine is presented, a survey of the related information sources of TCM, a review and discussion of the state of the art and the development of text mining techniques with applications toTCM, and a discussion ofThe research issues around TCM text mining and its future directions are presented.

TL;DR: The program's ethical, legal and social issues consultancy identified challenges to acceleration of action-focused PHRs: personal control of privacy choices, management of privacy in home conditions, and rebalancing power structures in shared decision making.

TL;DR: This paper presents a virtual orthopedic drilling simulator that was designed to provide visiohaptic interaction with virtual bones and was shown that the simulator was able to produce a learning effect that transfers to real-world drilling.

TL;DR: The mechanism of the preclinical anti-cancer drug parthenolide (PTL) is investigated by analyzing the differential expression of the fundamental components of the authors' fundamental components by using independent component analysis (ICA).

TL;DR: This work addresses the semantic interoperability of two EHR standards: OpenEHR and ISO EN 13606 by addressing the dual model approach which distinguishes information and knowledge, this being represented through archetypes.

TL;DR: This work defines informatics as the science of information, where information is data plus meaning, which distinguishes the field from related fields, such as computer science, statistics and biomedicine, which have different objects of study.

TL;DR: This study proposes a new ensemble method, called ensemble gene selection by grouping (EGSG), to select multiple gene subsets for the classification purpose, and shows that the method has comparable classification performance to other gene selection methods, and is more stable than the random one.

TL;DR: Comparisons of four methods employed during the development of outpatient clinical documentation software suggest that no single method identifies all or most problems, and each approach is optimal for evaluations at a different stage of design and characterizes different usability aspect.

TL;DR: An automated approach that uses syntax and semantics to identify explicit claims automatically and measure the degree to which each feature contributes to the overall precision and recall is introduced, showing that a combination of semantics and syntax is required to achieve the best system performance.

TL;DR: The aim of this book is to provide a history of web exceptionalism from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which descriptions of “Web 2.0” began to circulate.

TL;DR: An automated method that assists in the diagnosis of Alzheimer's disease and also supports the monitoring of the progression of the disease is presented.

TL;DR: This work develops and test dynamic programming formulations for adherence measurement in clinical pathways--based on partially ordered data in medical records and pathway definitions and analyze clinical pathway adherence at the Cardiovascular Center of Maastricht University Medical Center.

TL;DR: It is hypothesize, based on protein annotations, that zinc and retinoic acid may play a role in migraine, and the ChemoText repository has promise as a data source for drug discovery.

TL;DR: People with diabetes had a mixture of positive and negative reactions to an automated and tailored messaging feedback system for self-management support and saw value in the mobile system as an adjunct to the Web-based program and traditional office-based care.

TL;DR: The issues raised by the first phase of Project HealthDesign projects are summarized, categorizing them into four topics: privacy and confidentiality, data security, decision support, and HIPAA and related legal-regulatory requirements.

TL;DR: An extension of the Fellegi-Sunter method that incorporates approximate field comparators in the calculation of field weights is introduced and its ability to find duplicate records previously identified in the data warehouse using different demographic fields and matching cutoffs is compared.

TL;DR: Evaluating the usability of emergency department (ED) software prototypes developed for Tablet personal computers (Tablet PCs) in order to keep electronic health records of patients errorless and accessible through mobile technologies confirmed the view that the usability evaluation results of iconic GUIs were better than those of non-iconic GUIs in terms of Nielsen's heuristic evaluation, effectiveness and user satisfaction.

TL;DR: The role of Bayes Theorem and Bayesian networks arising in a medical negligence case brought by a patient who suffered a stroke as a result of an invasive diagnostic test is explained and a wide range of alternative scenarios are supported.

TL;DR: The design choices underlying the models are described, which enable them to identify temporal patterns, predict outcomes, and test clinical hypotheses, and are characterized by the choice of the dynamic hierarchical Bayesian network structure and the use of logistic regression equations in estimating the transition probabilities.

TL;DR: A framework for selecting patient-oriented technologies in developing countries and can be applied to health interventions across health domains to explore how and whether available technologies can support delivery of the associated types of interventions and with the target populations.

TL;DR: A framework that can monitor, detect, and handle exceptions that occur during normal CIG execution and can potentially prevent them from developing into medical errors is developed.

TL;DR: The design and evaluation of the Colorado Care Tablet is discussed, a Personal Health Application that helps older adults and their lay caregivers manage their medication regimes during care transitions by designing an application based on their real world artifacts and workflows.

TL;DR: Experimental evaluations with other state-of-the-art PPI extraction systems tested on the DIP corpus indicate that BioPPISVMExtractor can substantially improve recall at the cost of a moderate decline in precision.