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Showing papers in "Journal of Clinical Epidemiology in 2000"


Journal ArticleDOI
TL;DR: Tests for small-study effects should routinely be performed in meta-analysis, particularly for moderate amounts of bias or meta-analyses based on a small number of small studies.

1,821 citations


Journal ArticleDOI
TL;DR: A comorbidity index that incorporates the diagnostic and procedure data contained in Medicare physician (Part B) claims and demonstrates the utility of a disease-specific index using an alternative method of construction employing study-specific weights.

1,602 citations


Journal ArticleDOI
TL;DR: A review of the literature suggests there are two major aspects of responsiveness, which characterizes the ability of a measure to change over a prespecified time frame and which reflects the extent to which change in a measure relates to correspondingchange in a reference measure of clinical or health status.

1,310 citations


Journal ArticleDOI
TL;DR: Urinary leakage is highly prevalent in an unselected female population in Norway and seven percent of the participating women have significant incontinence and should be regarded as potential patients.

1,171 citations


Journal ArticleDOI
TL;DR: The design of the meta-analysis itself, and the studies included in it, are shown to be important among a number of sources of publication bias.

898 citations


Journal ArticleDOI
TL;DR: Comparing the QL of a wide range of chronic disease patients found that patients who were older, female, had a low level of education, were not living with a partner, and had at least one comorbid condition, in general, reported the poorest level of QL.

648 citations


Journal ArticleDOI
TL;DR: The WHOQOL-100 (U.S. version) as discussed by the authors is a 100-item self-report instrument consisting of 24 subscales within six domains: Physical, Psychological, Independence, Social, Environment, and Spiritual.

494 citations


Journal ArticleDOI
TL;DR: This study provides no evidence that language restricted meta-analyses lead to biased estimates of intervention effectiveness and encourages others to replicate this study using different sampling frames, clinical topics and interventions.

464 citations


Journal ArticleDOI
TL;DR: The question of whether devices have enhanced placebo effects and, if so, whether so, what the implications may be is examined.

423 citations


Journal ArticleDOI
TL;DR: It is demonstrated that the shape of a funnel plot is largely determined by the arbitrary choice of the method to construct the plot, and that the discrepancies between large trials and corresponding meta-analyses and heterogeneity in meta-Analyses may also be determined by how they are evaluated.

348 citations


Journal ArticleDOI
TL;DR: Obesity seems to be a mechanical rather than a systemic risk factor for OA with the knee joint being especially susceptible to osteoarthritis.

Journal ArticleDOI
TL;DR: This study shows how the cost diary might be used successfully in cost-effectiveness studies, and the results for the three alternative periods of data collection were not significantly different, they were only moderately correlated.

Journal ArticleDOI
TL;DR: The ASK is a valid and responsive outcome measure that permits 5- to 15-year-old children physical functioning in the community to be assessed accurately by mail and will enable clinical studies to measure outcome not only in a manner that is relevant to patients, but also in a way that is sensitive to small amounts of change and is practical and inexpensive.

Journal ArticleDOI
TL;DR: It is suggested that investigators concentrate on obtaining populations with trait prevalence near 50% rather than searching for statistical indices to rescue or excuse inefficient experiments.

Journal ArticleDOI
TL;DR: Clinical data abstracted from most Canadian hospitalization databases can provide reliable information regarding baseline co-morbid conditions believed to influence survival in a population undergoing percutaneous coronary interventions, suggesting minimal misclassification.

Journal ArticleDOI
TL;DR: It is shown that Dupuytren's disease is common in the Icelandic population and occupation and lifestyle seem to be related to the disease.

Journal ArticleDOI
TL;DR: The results suggest that the SF-36 is a useful scale for the differentiated clinical forms of ischemic cardiopathy, with the additional capability of reflecting the level of anxiety in these patients.

Journal ArticleDOI
TL;DR: The data indicate the CES-D would have greater validity among this diverse group of older men and women after removal of the crying item and two interpersonal items.

Journal ArticleDOI
TL;DR: High levels of physical activity (running 20 or more miles per week) were associated with osteoarthritis among men under age 50 after controlling for body mass index, smoking, and use of alcohol or caffeine, and no relationship was suggested among women or older men.

Journal ArticleDOI
TL;DR: Health-related quality of life (HRQL) is impaired in syncope patients and the degree of impairment is proportional to syncope frequency and the EuroQol EQ-5D was completed by 136 patients.

Journal ArticleDOI
TL;DR: More positive than negative trials of complementary therapies are published, except in high-impact factor MM-journals, which should be taken into account when the literature on complementary therapies is being examined.

Journal ArticleDOI
TL;DR: Some defining characteristics of the main choices of effect measure [risk difference (RD), relative risk (RR), and odds ratio (OR)] for binary data are presented and compared, with consideration of both the clinical and statistical perspectives.

Journal ArticleDOI
TL;DR: The search strategy using the Mesh term "sensitivity and specificity" (exploded) and the text words "specificity," "false negative," and "accuracy" has both higher sensitivity and specificity than the previously published strategy.

Journal ArticleDOI
TL;DR: The presented results suggest that the SDQ is as responsive as the compared outcome measures, and therefore is ready for use in clinical trials.

Journal ArticleDOI
TL;DR: The high degree of social deprivation in Glasgow is suggested as a major explanation of the high H. pylori prevalence found there, and the independent relationship with smoking suggests a possible second source of spread of infection in later years.

Journal ArticleDOI
TL;DR: Among the free-living frail elderly, weight loss >/=5 kg is an important predictor of early institutionalization after controlling for social network, health, and functional status.

Journal ArticleDOI
TL;DR: The sensitivity of using physician claims data for injury ascertainment was examined in a cohort of elderly who were treated in the emergency department of one of 10 hospitals for injuries in 1993-1994, finding the combination of treatment procedure codes and diagnostic codes provided the most sensitive measure of injury occurrence.

Journal ArticleDOI
TL;DR: A UK version of the McMaster IBDQ is developed and validates and supports the reliability, validity, reproducibility, and responsiveness of the UK I BDQ and its acceptability to patients in UK.

Journal ArticleDOI
TL;DR: The risk of pain onset among women was evident in relation to BMI at baseline (age 23) and cannot therefore be explained by an effect of back pain on adiposity.

Journal ArticleDOI
TL;DR: Overall, being older, reporting better functional status, and having fewer depressive symptoms were significantly associated with higher quality of life, although the association was much lower for adults with AIDS and younger well adults where ceiling effects were observed in functional status.