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Showing papers in "Journal of Critical Care in 1987"


Journal Article•DOI•
TL;DR: A prospective controlled randomized study of the use of extracorporeal membrane oxygenation to treat newborns with respiratory failure using the "randomized play-the-winner" statistical method, which allows lung rest and improves survival compared to conventional ventilator therapy in newborn infants with severe respiratory failure.

549 citations


Journal Article•DOI•
TL;DR: It is concluded that surfactant supplementation prior to the first breath is feasible and is of value as protection against the respiratory distress syndrome and the negative effects of hypoxia and ventilatory support.

284 citations


Journal Article•DOI•
TL;DR: Calf lung surfactant extract instillation at birth appears to be an effective material and method of preventing hyaline membrane disease in extremely premature infants.

187 citations


Journal Article•DOI•
TL;DR: Early thrombolysis by intracoronary streptokinase leads to a smaller infarct size estimated by enzyme release, preserves left ventricular function at the second week and leads to improved 1 year survival.

143 citations


Journal Article•DOI•
TL;DR: The presence of both circulating xanthine oxidase and its substrate demonstrates the potential for intravascular oxygen metabolite production, which may then cause tissue injury in ARDS.

101 citations


Journal Article•DOI•
TL;DR: It is concluded that compromise of systemic and pulmonary defense by impaired hepatic RES performance and hepatocyte function may both predispose to ARDS and critically modulate its resolution.

93 citations


Journal Article•DOI•
TL;DR: The extent and consequence of misdiagnosis of wide complex tachycardia (QRS, 120 ms or more; heart rate, 100 or more beats/min) presenting emergently were assessed and Verapamil is commonly administered in these circumstances and is frequently associated with a poor outcome.

69 citations


Journal Article•DOI•
TL;DR: To determine if electrocardiographic findings characterize tricyclic antidepressant (TCA) overdose and cardiotoxicity, 25 patients suspected of taking an overdose of TCA were studied.

49 citations


Journal Article•DOI•
TL;DR: The treatment groups in this study were specifically designed to evaluate the use of dextrose in an experimental model mimicking the clinical setting of cardiac arrest.

48 citations


Journal Article•DOI•
TL;DR: In this study, significant tracheal damage occurred with all forms of high-frequency ventilation, and the BLP, the ventilator operating at the fastest rate, produced the greatest loss of surface cilia and depletion of intracellular mucus.

46 citations


Journal Article•DOI•
TL;DR: Optimal use of the clinical information by discriminant analysis resulted in significant improvement in the prediction of hemodynamic status in these critically ill patients when compared to physician judgments.

Journal Article•DOI•
TL;DR: In this paper, an unblinded trial of intravenous streptokinase (SK) in early acute myocardial infarction, 11 806 patients in one hundred and seventy-six coronary care units were enrolled over 17 months.

Journal Article•DOI•
TL;DR: Verapamil should not be used in patients with atrial fibrillation and preexcited ventricular complexes, and the presence of accessory atrioventricular pathways capable of rapid antegrade conduction in each patient is confirmed.



Journal Article•DOI•
TL;DR: Serial simultaneous hemodynamic and echocardiographic observations at multiple points during pericardiocentesis in a smaller subgroup (5 patients) suggest that the hemodynamic effects of RV diastolic collapse in cardiac tamponade are mediated by an increase in intrapericardial pressure.

Journal Article•DOI•
TL;DR: The effects of dobutamine and intravenous milrinone on systemic hemodynamics, coronary blood flow and myocardial metabolism were studied in patients with severe congestive heart failure and both drugs significantly decreased coronary vascular resistance and my Cardiac Index but did not change myocardian lactate extraction.

Journal Article•DOI•
TL;DR: A spectrum of respiratory complications encompassed by the popular collective term, inhalation injury is delineated, which includes diverse problems with heterogeneous clinical and pathologic manifestations, but conveys the acuity of illness, its genesis, and ominous prognosis.

Journal Article•DOI•
TL;DR: A common factor of cardiac compression by the lung during inspiration altering diastolic intraventricular distribution of the LV preload is suggested and the question of whether respiratory-induced changes in LV geometry may independently modulate LV systolic pump function is raised.

Journal Article•DOI•
TL;DR: When applied to an independent AMI data base, as well as to the summed results of 6 previously reported series that identified predictors of CHB during AMI, a similar incremental risk ofCHB as predicted by the risk score method was demonstrated.



Journal Article•DOI•
John T. Fahey1, George Lister1•
TL;DR: The experimental observations that have described the local and systemic responses and metabolic consequences of a low cardiac output are discussed and the findings are related to the understanding of patients with inadequate systemic perfusion to focus on disruptions in 0, delivery consequent to limitations in blood flow.


Journal Article•DOI•
TL;DR: After amrinone treatment, afterload reduction occurs in all patients with severe CHF and is the sole effect in some, and the effects of amrin one and nitroprusside on hemodynamic and radionuclide measurements were compared.

Journal Article•DOI•
TL;DR: The automatic implantable cardioverter-defibrillator continuously monitors the heart, identifies malignant ventricular tachyarrhythmias and then delivers electrical countershock to restore normal rhythm.


Journal Article•DOI•
TL;DR: It is concluded that in porcine septic shock pulmonary microvascular permeability is increased, but the microv vascular albumin flux and thus plasma extravasation increased more in the abdomen than in the lungs.

Journal Article•DOI•
TL;DR: In this paper, intravenous amiodarone was used to control life-threatening refractory cardiac arrhythmias in critically ill patients with impaired left ventricular function.

Journal Article•DOI•
TL;DR: In this paper, the authors measured the effect of inadvertent positive end-expiratory pressure (PEEP) on lung mechanics and gas exchange, and measured the compliance of the respiratory system and blood gases.