Showing papers in "Journal of Critical Care in 2001"

TL;DR: In this cohort of long-term intensive care patients, screening for iron, B12, and folate deficiency identified potentially correctable abnormalities in more than 13% of patients and should be considered in those who are anticipated to have long ICU stays.

TL;DR: This questionnaire has some measure of reliability and validity and is feasible to administer to next of kin of critically ill patients and is shown to be reliable.

TL;DR: Recent clinical trials have supported the use of antithrombin and activated protein C supplementation in DIC associated with severe sepsis, and future efforts may be directed at combining 2 or more agents to achieve prompt and successful reversal of DIC.

TL;DR: The patients receiving sedatives in the ICU are not comparable with those receiving only opiates or nothing, due to the different clinical condition, and sedation does not influence the incidence of factual, sensation, and emotional memories of ICU admitted patients.

TL;DR: It is considered that Gelofusine increases the urinary excretion of proteins, in particular those of low molecular weight, when analyzing proteinuria in patients in the intensive care unit.

TL;DR: The inspiratory pattern in Pra does not predict the response to cardiac output to PEEP in individual patients, most likely because of reflex adaptations in the circuit that occur with the application of PEEP.

TL;DR: VTE prevention for surgical ICU patients within the first postoperative week appear to be individualized, and influenced by current and future risks of thrombosis and bleeding.

TL;DR: Direct PEJ placement is a safe and reliable device that can be successfully placed in critically ill, mechanically ventilated patients and with this procedure, all patients can meet their nutritional requirements and eliminate the need for TPN.

TL;DR: ICU attendings predicted most accurately and consistently the final outcome of patients, and ICU fellows estimated outcome more reliably than the primary service, indicating that predictions of outcome in critically ill patients made within days of admission are statistically valid but not sufficiently reliable to justify irrevocable clinical decisions at present.

TL;DR: Use of negative filter results in the temperature-dependent generation of bradykinin, which becomes a potential anaphylatoxin when warm blood is used.

TL;DR: The results suggest that pathologic aggravation of acute hepatic failure are related to changes in the FasL/Fas system and that TNF-alpha and sFasL, in particular, may play hepatoprotective roles.

TL;DR: After adjustment for mortality confounding factors, medical versus surgical admittance status was not a significant determinant of VAP mortality.

TL;DR: In this paper, the authors delineate early respiratory predictors of mortality in children with hemato-oncology malignancy who developed acute respiratory distress syndrome (ARDS) and demonstrate that peak inspiratory pressure, positive end-expiratory pressure (PEEP), and ventilation index values could distinguish outcome by day 3.

TL;DR: The low incidence of stress ulcer-related bleeding might be related to the prevention of H. pylori-associated stress lesions by effective suppression of this microorganism, but further studies are warranted to test this hypothesis.

TL;DR: ARDS in patients with blunt and penetrating trauma showed similar trends in ICU mortality, complications, and resource utilization, and the ARDS mortality rate decreased over the time period studied in both blunt and penetrate trauma.

TL;DR: The beliefs and attitudes of intensivists regarding pleural effusions and exploratory thoracentesis are divergent and may be due to the lack of precise guidelines on the topic and prompt the design of further studies to establish precisely the epidemiology and causes of Pleural effusion in ICU patients.

TL;DR: The leukocyte-independent endothelial damage during early endotoxemia can be inhibited efficiently by the 5-HT-receptor antagonist methysergide, indicating that serotonin plays an important role in that pathophysiology.

TL;DR: Adenosine appears to have an antiarrhythmogenic effect both in supraventricular and ventricular rhythm disturbances during myocardial infarction, where huge amounts of adenosine are present in ischemic regions, asystole may respond to adenosines antagonists.

TL;DR: Hemorrhagic shock significantly increased circulating endogenous heparin activity, attenuating the thrombotic response to hemorrhage in rabbits and suggesting Heparin-mediated regulation of hemostasis may serve as a protective mechanism in shock states.

TL;DR: The analysis of AKBR trend in combination with a measurement of blood lactate level in early postoperative period appears to be useful for the assessment of the severity of illness in pediatric patients following heart surgery.

TL;DR: Isoflurane, enfluranes, and halothane exert significantly different effects on vasoregulation of skeletal muscle arterioles in the endotoxemic rat, and these effects set patients at high risk for hemodynamic deterioration.

TL;DR: This study suggests that L-canavanine induces tissue hypoperfusion and ischemia with concomitant hypersecretion of ET-1 in dogs with endotoxic shock.

TL;DR: There appears to be complex interactions among psychologic and environmental mediators that influence physician participation in hospital quality initiatives and the CQIQ shows reasonable measurement properties and should be generalizable to physicians in other academic institutions.

TL;DR: A large number of hospitals across the United States have too few ICU patients to accurately assess quality of care, and Solucient performs the 100 Top Hospitals: Benchmarks for Success studies to create useful benchmarks for measuring hospital performance nationally.

TL;DR: There is an increase in the alveolar LM- PLA2 at inflammatory phase after HCI aspiration, suggesting the pathophysiologic role of LM-PLA2 in the acute lung injury.

TL;DR: The mortality rate was considerably lower in nonoliguric septic patients who received continuous venovenous hemofiltration early in the course of the disease, and the improved survival rate may be due to the ability of CVVH to eliminate mediators involved in the septic process, thus averting the multiple system organ failure consequent to septic insult.

TL;DR: The leukocyte-independent microvascular damage during early endotoxemia cannot be inhibited efficiently by the H1-receptor antagonist diphenhydramine, indicating that histamine seems to play only a minor role in that pathophysiology.

TL;DR: This issue of the JCC serves as the inaugural launch of the Journal of Critical Care, and the editorial by Dr. John Lavis and Dr. Sean Keenan provides a framework and rationale supporting the integration of HSR and CC medicine, and this short descriptive article offers some of the logistical changes in the J CC.

TL;DR: Health services research has the potential to improve the care provided to patients in critical care settings by informing the decisions of managers and policy makers who establish many of the rules within which critical care is provided, according to the authors.